Volume 7 Supplement 1

International Society on Brain and Behaviour: 3rd International Congress on Brain and Behaviour

Open Access

The comparison between therapeutic effects of different classes of antidepressant drugs in treatment of genetical and reactional depression

  • Parviz Molavi1,
  • Karimollahi Mansoureh1,
  • M Faridi1,
  • H Mohammadnia1,
  • P Dailami1,
  • R Arab1 and
  • F Derakshani1
Annals of General Psychiatry20087(Suppl 1):S315

DOI: 10.1186/1744-859X-7-S1-S315

Published: 17 April 2008

Background

Depression as a common psychiatric disorder can occur in two types: endogenous or genetic and exogenous or reactional. These two types of depression, from the point of view of response speed to treatment and type of appropriate drug for treatment are different. This study has been executed to compare therapeutic effects of different classes of anti-depressant drugs in treatment of genetic and reactional depression.

Materials and methods

Present survey is a clinical-trial study, a completely randomly block type, that has performed on 30 patients (male and female). Selection of study sample accomplished randomly among unipolar depressed patients that has referred to Ardabil's psychiatry clinic diagnosed based on DSM-IV criteria. Researcher - Made questionnaire, Beck, and Catelle depression test were used to collect data. To analyze data, for completely randomly blocked designs, two-factor variance analysis method and F test were used.

Results

This study showed that genetical depression does not response treatment rapidly and its response type is not good and persistent. From the point of view of time, reactional depression has a delaying response but its response type is good and persistent. In addition, no difference was observed in efficacy of different classes of drugs for treatment of these two types of depression. The results of this research showed that there is no difference between treatment response of two types of depression (genetical and reactional).

Conclusions

There is no preference in efficacy of different classes of drugs in treatment of these two types of depression.

Authors’ Affiliations

(1)
Ardabil Medical sciences University

Copyright

© Molavi et al.; licensee BioMed Central Ltd. 2008

This article is published under license to BioMed Central Ltd.

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