Isotretinoin and psychopathology: a review

Table 4 Number of cases of suicide, attempted suicide and suicide ideation associated with acne medications.

Acne medication	Period	Suicide	Suicide attempt	Suicide ideation	Total	Estimated patient exposure	Adverse drug reactions per million
Dianette	1980 to 1998	-	3	-	3
Doxycycline	1965 to 1998	-	0	-	0
Minocycline	1971 to 1998	-	2	-	2
Oxytetracycline	1965 to 1998	-	0	-	0
Tetracycline	1964 to 1998	-	3	-	3
Total combined		-	8	-	8	300 million	0.03
Roaccutane	1982 to 1998	47	67	56	170	6 million	28.34

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