Table 5 Common metabolic parameters before and after treatment in patients with schizophrenia, Grouped by early treatment response or not
Parameters | Group A (n = 70) | Group B (n = 73) | Time F (P value) | Subgroup F (P value) | Time × subgroup F (P value) | ||
|---|---|---|---|---|---|---|---|
Baseline | 6th week | Baseline | 6th week | ||||
BW—kg | 60.39 ± 11.05 | 60.71 ± 10.62 | 57.48 ± 11.20 | 58.32 ± 11.46 | 0.20 (0.659) | 4.08 (0.044*) | 0.04 (0.841) |
BMI—kg/m2 | 21.80 ± 3.23 | 22.08 ± 3.24 | 21.50 ± 3.45 | 21.78 ± 3.72 | 0.48 (0.489) | 0.54 (0.463) | 0.00 (0.986) |
AC—cm | 80.07 ± 8.58 | 80.54 ± 8.84 | 77.11 ± 9.76 | 84.03 ± 9.87 | 0.03 (0.858) | 8.67 (0.004*) | 0.06 (0.803) |
BUN—mmol/L | 3.80 ± 1.21 | 3.68 ± 1.20 | 3.73 ± 1.32 | 3.61 ± 1.28 | 0.27 (0.607) | 0.68 (0.409) | 0.00 (0.997) |
BC—mmol/L | 59.22 ± 12.38 | 70.31 ± 21.82 | 63.61 ± 19.38 | 70.33 ± 21.83 | 22.84 (< 0.001*) | 6.84 (0.009*) | 0.49 (0.486) |
UA—mmol/L | 383.27 ± 106.46 | 390.70 ± 123.44 | 396.17 ± 107.91 | 433.32 ± 122.47 | 4.13 (0.043*) | 2.66 (0.104) | 1.18 (0.278) |
TC—mmol/L | 3.83 ± 0.73 | 4.76 ± 1.13 | 3.84 ± 0.77 | 4.64 ± 1.13 | 57.84 (< 0.001*) | 0.20 (0.656) | 0.34 (0.560) |
TG—mmol/L | 1.13 ± 0.54 | 1.97 ± 1.36 | 1.07 ± 0.61 | 2.86 ± 1.94 | 78.42 (< 0.001*) | 7.88 (0.005*) | 10.16 (0.002*) |
HDL—mmol/L | 1.18 ± 0.25 | 0.98 ± 0.28 | 1.18 ± 0.23 | 0.93 ± 0.20 | 64.98 (< 0.001*) | 1.06 (0.305) | 0.70 (0.404) |
LDL—mmol/L | 2.15 ± 0.59 | 2.57 ± 0.83 | 2.22 ± 0.62 | 2.56 ± 0.84 | 10.67 (0.001*) | 0.80 (0.371) | 2.67 (0.103) |
FBG—mmol/L | 4.32 ± 0.68 | 5.31 ± 1.04 | 4.41 ± 1.04 | 5.99 ± 1.65 | 74.58 (< 0.001*) | 16.39 (< 0.001*) | 1.24 (0.266) |
PRL—ng/mL | 19.08 ± 14.78 | 37.92 ± 37.79 | 18.31 ± 12.14 | 38.37 ± 25.08 | 30.77 (< 0.001*) | 2.74 (0.099) | 0.90 (0.344) |