Table 1 Patient baseline characteristics in included studies
Study (reference) | PRISMA-3 OLE [24] | Gopal 2010 [29] | Kane 2012 [30] | |||
|---|---|---|---|---|---|---|
Patient cohort | Unstablea N = 55 | Stabilizedb N = 119 | Stablec N = 41 | All N = 215 | All N = 388 | AOM arm N = 269 |
Age [Mean (SD)] | 38.2 (10.0) | 40.3 (11.5) | 36.7 (9.9) | 39.1 (10.9) | 37.3 (10.8) | 40.1 (11.0) |
Sex [n (%)] | ||||||
Male | 31 (56.4) | 76 (63.9) | 24 (58.5) | 131 (60.9) | 209 (54.0) | 162 (60.2) |
Female | 24 (43.6) | 43 (36.1) | 17 (41.5) | 84 (39.1) | 179 (46.0) | 107 (39.8) |
Race [n (%)] | ||||||
White | 44 (80.0) | 97 (81.5) | 41 (100.0) | 182 (84.7) | 269 (69.0) | 152 (56.5) |
Black | 11 (20.0) | 21 (17.6) | 0 (0.0) | 32 (14.9) | 41 (11.0) | 59 (21.9) |
Asian | 0 (0.0) | 1 (0.8) | 0 (0.0) | 1 (0.5) | 72 (19.0) | 45 (16.7) |
Other | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 6 (2.0) | 13 (4.8) |
Age at diagnosis [Mean (SD)] | 27.7 (7.5) | 28.5 (8.5) | 27.9 (7.7) | 28.2 (8.1) | 26.8 (8.5) | 25.8 (8.3) |
PANSS total score [Mean (SD)] | 82.3 (12.2) | 70.0 (14.3) | 60.3 (8.2) | 71.3 (14.8) | 58.2 (18.2) | 54.5 (NR) |
CGI-S score [Mean (SD)] | 4.1 (0.9) | 3.4 (0.9) | 2.8 (0.5) | 3.5 (0.9) | 3.0 (median) | 2.9 (NR) |
BMI [Mean (SD)] | 27.6 (4.7) | 27.0 (4.9) | 25.5 (3.7) | 26.9 (4.7) | 27.2 (5.6) | 28.1 (6.9) |