Item | Before treatment (n = 364) | 2–4 weeks of treatment (n = 362) | 6–8 weeks of treatment (n = 349) | 12 weeks of treatment (n = 322) |
---|---|---|---|---|
Anxiety-depression | 10.0 ± 3.45 | 8.0 ± 2.75** | 6.8 ± 2.49** | 5.8 ± 1.96** |
Anergia | 10.2 ± 3.12 | 8.4 ± 2.55** | 7.2 ± 2.39** | 6.2 ± 2.03** |
Thought disturbance | 12.7 ± 4.08 | 9.5 ± 3.52** | 7.7 ± 3.09** | 6.3 ± 2.58** |
Activation | 6.6 ± 2.81 | 4.8 ± 1.97** | 4.1 ± 1.50** | 3.6 ± 1.21** |
Hostility-suspiciousness | 10.6 ± 3.78 | 7.3 ± 2.78** | 5.8 ± 2.41** | 4.7 ± 1.81** |
BPRS total score | 50.1 ± 11.95 | 38.0 ± 9.68** | 31.5 ± 8.98** | 26.6 ± 7.43** |