Table 1 Changes in gut microbiota in different animal models and humans with postpartum depression (PPD)
From: The role of gut microbiota in the pathogenesis and treatment of postpartum depression
Experimental subjects | Increased abundance of gut microbiota | Decreased abundance of gut microbiota | References |
|---|---|---|---|
HFD-induced PPD in C57BL6/J mice | p_Actinobacteria p_Proteobacteria p_Deferribacteres p_unkunown_Unassigned p_Verrucomicrobia g_Lactobacillus g_Desulfovibrionaceae g_Christensenellaceae | p_Bacteroidetes p_Cyanobacteria p_TM7 g_unknown_S24-7 g_F16 g_Flexispira | [29] |
28 patients with PPD and 16 healthy controls (HCs) | p_Actinobacteria p_Bacteroidetes f_Enterobacteriaceae | p_Firmicutes f_Faecalibacterium f_Phascolarctobacterium f_Butyricicoccus f_Lachnospiraceae g_Faecalibacterium g_Phascolarctobacterium g_Butyricicoccus g_Megasphaera | [51] |
Stress-induced PPD in BALB/c mice | p_Deferribacteres c_Deferribacteres o_Deferribacterales g_Desulfovibrio g_Alistipes g_Unclassified_Lachnospiraceae, g_Mucispirillum s_Eubacterium plexicaudatum, s_Eubacterium sp. 14.2 s_Lachnospiraceae bacterium 3.1 s_Mucispirillum schaedleri, s_Desulfovibrio piger | f_Rikenellaceae g_Turicibacter s_Bifidobacterium pseudolongum s_uncultured bacterium | [54] |
GDM-induced PPD in SD rats | f_Prevotellaceae f_Ruminococccaceae f_Peptococciaceae 1 f_Coriobacteriaceae g_Prevotella g_Lactobacillus g_Paraprevotella | p_Actinobacteria p_Clostridiales f_Lachnospirnaceae g_Helicobacter g_Clostridium XlVa g_Ruminococcus | [50] |