Table 6 Predictors of antipsychotic medicine switch in ambulatory patients with schizophrenia at five comprehensive specialized hospitals, Northwest Ethiopia, 2021 (n = 414)
Variable | Category | Antipsychotic switch | COR (95% CI) | AOR (95% CI) | p-value | |
|---|---|---|---|---|---|---|
Yes (%) | No (%) | |||||
Gender | Male | 116 (26) | 104 (46) | 1.89 (1.27–2.80) | 2.58 (1.46–4.55) | 0.001** |
Female | 72 (38.3) | 122 (54) | 1 | 1 | Â | |
History of admission in the past 12 months | Yes | 139 (74) | 102 (45.1) | 3.44 (2.27–5.23) | 3.00 (1.47–5.71) | 0.002** |
No | 49 (26) | 124 (54.9) | 1 | 1 | Â | |
Groups of medication in the past 12 months | FGAs | 140 (74.5) | 86 (38) | 4.74 (3.22–7.44) | 3.34 (1.76–6) | 0.000*** |
SGAs | 48 (25.5) | 140 (62) | 1 | 1 | Â | |
History of relapse in the past 12 months | Yes | 76 (40) | 109 (48.2) | 0.73 (0.32–0.75) | 2.34 (1.16–4.68) | 0.016* |
No | 112 (60) | 117 (51.8) | 1 | 1 | Â | |