Psychometric properties of the Clinical Assessment Interview for Negative Symptoms (CAINS) in patients with depression and its relationship to affective symptoms

Table 4 Correlations with affective domains and related measures (n = 51)

	CAINS total Live rating	CAINS-MAP Live rating	CAINS-EXP Live rating
BPRS, live rating (not blinded)^‡ Affective symptoms subscale^†	0.26 (p = 0.063)	0.39 (p = 0.005)	− 0.07 (p = 0.634)
MADRS-S total score	0.34 (p = 0.015)	0.50 (p < 0.001)	− 0.08 (p = 0.577)
MADRS-S anhedonia (Lassitude and Inability to feel)	0.29 (p = 0.039)	0.44 (p = 0.001)	− 0.08 (p = 0.567)
BPRS, live rating (not blinded)^‡ Anxiety and Tension items	0.16 (p = 0.253)	0.22 (p = 0.113)	− 0.02 (p = 0.919)
MADRS-S Inner tension	0.13 (p = 0.358)	0.24 (p = 0.095)	− 0.10 (p = 0.504)
Maudsley Staging Method	0.22 (p = 0.115)	0.09 (p = 0.515)	0.30 (p = 0.031)
CGI^‡	0.64 (p < 0.001)	0.45 (p < 0.001)	0.60 (p < 0.001)
EQ-VAS	− 0.27 (p = 0.052)	− 0.33 (p = 0.018)	− 0.05 (p = 0.744)
Sheehan Disability Scale	− 0.19 (p = 0.182)	− 0.22 (p = 0.129)	− 0.05 (p = 0.714)
Verbal fluency	− 0.27 (p = 0.059)	− 0.12 (p = 0.386)	− 0.34 (p = 0.014)
Digit Symbol Substitution Test	− 0.14 (p = 0.338)	− 0.09 (p = 0.542)	− 0.14 (p = 0.329)

Pearson correlation coefficients (p-values)
CAINS Clinical Assessment Interview for Negative Symptoms, MAP Motivation and Pleasure Subscale, EXP Expression Subscale, BPRS Brief Psychiatric Rating Scale, MADRS-S Montgomery Asberg Depression Rating Scale-Self Rating, CGI Clinical Global Impression, EQ-VAS EuroQol Group Visual Analogue Scale
^‡Same rater as the CAINS rating
^†Affective Symptoms Subscale comprises the items Depression, Suicidality and Guilt

ISSN: 1744-859X