Table 2 Discontinuation due to adverse effects and duration of treatment
Stopped due to side effects | Time taking medication | Total | |||
|---|---|---|---|---|---|
< 3 months % | 4–12 months % | 1 + yearsa % | |||
Sertraline | Yes | 1086 (37·8) | 831 (29·0) | 933 (32·5) | 2870 |
No | 293 (8·3) | 780 (22·0) | 2462 (69·3) | 3551 | |
Citalopram | Yes | 422 (37·1) | 360 (31·6) | 340 (29·9) | 1139 |
No | 125 (8·8) | 312 (21·9) | 972 (68·3) | 1424 | |
Escitalopram | Yes | 714 (37·7) | 626 (33·0) | 543 (28·6) | 1896 |
No | 249 (8·3) | 746 (25·0) | 1966 (65·9) | 2984 | |
Paroxetine | Yes | 303 (38·2) | 219 (27·6) | 258 (32·5) | 794 |
No | 69 (7·9) | 192 (22·0) | 600 (68·8) | 872 | |
Fluoxetine | Yes | 681 (38·4) | 554 (31·2) | 524 (29·5) | 1774 |
No | 203 (9·8) | 489 (23·7) | 1348 (65·4) | 2061 | |
Venlafaxine | Yes | 611 (30·3) | 616 (30·5) | 774 (38·4) | 2017 |
No | 157 (6·1) | 399 (15·5) | 1996 (77·5) | 2575 | |
Desvenlafaxine | Yes | 428 (39·7) | 341 (31·6) | 304 (28·2) | 1078 |
No | 137 (7·9) | 341 (19·7) | 1242 (71·9) | 1727 | |
Duloxetine | Yes | 396 (40·8) | 296 (30·5) | 262 (27·0) | 971 |
No | 116 (8·7) | 269 (20·3) | 923 (69·6) | 1326 | |
Amitriptyline | Yes | 354 (43·5) | 230 (28·3) | 225 (27·6) | 814 |
No | 131 (17·2) | 199 (26·1) | 426 (55·9) | 762 | |
Mirtazapine | Yes | 644 (51·2) | 352 (28·0) | 241 (19·2) | 1258 |
No | 150 (16·0) | 240 (25·6) | 532 (56·8) | 936 | |