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Table 2 The global age-specific incidence of MDD for both sexes in 2019

From: Sex difference in incidence of major depressive disorder: an analysis from the Global Burden of Disease Study 2019

Age (years)

Incident cases (95% confidence interval) (thousands)

Incidence rates (95% confidence interval) (per 100,000)

Risk ratio (95% confidence interval)

Male

Female

Male

Female

All age

103,718.7 (90,683.7 to 118,044.6)

171,085.1 (150,207.7 to 195,228.6)

2672.5 (2336.6 to 3041.6)

4436.3 (3894.9 to 5062.3)

1.660 (1.660 to 1.660)

 < 5

5.7 (2.1 to 13.7)

6.5 (2.5 to 15.6)

1.7 (0.6 to 4.0)

2.0 (0.8 to 4.9)

1.236 (1.193 to 1.281)

5–9

363.7 (167.5 to 652.5)

578.3 (281.3 to 996.3)

107.6 (49.6 to 193.1)

182.6 (88.8 to 314.5)

1.696 (1.689 to 1.703)

10–14

3151.0 (1775.0 to 4940.0)

5654.4 (3332.6 to 8764.1)

951.0 (535.7 to 1490.9)

1819.0 (1072.1 to 2819.4)

1.913 (1.910 to 1.915)

15–19

7670.5 (5468.0 to 10,599.0)

12,412.3 (8857.0 to 17,048.1)

2413.8 (1720.7 to 3335.3)

4113.3 (2935.1 to 5649.6)

1.704 (1.703 to 1.706)

20–24

9608.7 (6737.4 to 12,958.4)

14,771.4 (10,235.2 to 19,851.8)

3156.9 (2213.6 to 4257.5)

4994.1 (3460.5 to 6711.8)

1.582 (1.581 to 1.583)

25–29

9378.2 (6690.7 to 13,057.8)

14,536.5 (10,075.4 to 20,201.2)

3077.1 (2195.3 to 4284.4)

4834.3 (3350.7 to 6718.2)

1.571 (1.570 to 1.572)

30–34

9510.1 (6924.6 to 13,025.0)

14,840.3 (10,767.3 to 20,408.6)

3136.9 (2284.0 to 4296.2)

4970.7 (3606.4 to 6835.7)

1.585 (1.583 to 1.586)

35–39

9335.2 (6962.1 to 11,988.3)

14,922.2 (10,990.4 to 19,213.8)

3425.3 (2554.5 to 4398.7)

5559.0 (4094.2 to 7157.7)

1.623 (1.622 to 1.624)

40–44

8941.8 (6501.5 to 11,449.3)

14,481.6 (10,552.2 to 18,632.4)

3594.8 (2613.7 to 4602.8)

5918.1 (4312.3 to 7614.4)

1.646 (1.645 to 1.648)

45–49

8824.9 (6920.3 to 10,811.4)

14,463.8 (11,412.3 to 17,670.0)

3702.1 (2903.1 to 4535.5)

6143.6 (4847.5 to 7505.5)

1.659 (1.658 to 1.661)

50–54

8404.8 (6728.4 to 10,316.1)

14,094.7 (11,362.2 to 17,207.6)

3862.7 (3092.3 to 4741.2)

6429.1 (5182.7 to 7849.1)

1.664 (1.663 to 1.666)

55–59

7495.0 (5744.7 to 9565.3)

12,812.3 (9790.2 to 16,163.7)

4101.0 (3143.2 to 5233.7)

6806.0 (5200.6 to 8586.3)

1.660 (1.658 to 1.661)

60–64

6472.9 (4992.6 to 8168.7)

11,089.9 (8517.8 to 13,871.4)

4254.2 (3281.3 to 5368.7)

6914.8 (5311.0 to 8649.0)

1.625 (1.624 to 1.627)

65–69

5376.5 (4440.3 to 6448.4)

9188.2 (7592.0 to 10,965.2)

4349.4 (3592.0 to 5216.4)

6807.7 (5625.1 to 8124.4)

1.565 (1.564 to 1.567)

70–74

3925.4 (3171.1 to 4810.2)

6645.1 (5425.4 to 8071.4)

4455.4 (3599.2 to 5459.7)

6713.4 (5481.2 to 8154.3)

1.507 (1.505 to 1.509)

75–79

2604.4 (1880.8 to 3381.4)

4628.0 (3367.1 to 5999.8)

4552.7 (3287.9 to 5911.1)

6625.7 (4820.6 to 8589.8)

1.455 (1.453 to 1.457)

80–84

1612.6 (1166.2 to 2071.0)

3222.3 (2321.2 to 4110.5)

4576.4 (3309.5 to 5877.2)

6551.5 (4719.3 to 8357.2)

1.432 (1.429 to 1.434)

85–89

741.8 (574.1 to 931.9)

1764.8 (1368.2 to 2193.8)

4555.4 (3525.7 to 5723.1)

6489.0 (5030.8 to 8066.3)

1.424 (1.421 to 1.428)

90–94

239.7 (170.9 to 327.3)

747.9 (535.9 to 1010.7)

4515.7 (3220.3 to 6166.3)

6475.7 (4639.7 to 8750.6)

1.434 (1.428 to 1.440)

95 plus

55.6 (33.3 to 83.2)

224.4 (137.7 to 333.3)

4356.9 (2609.9 to 6520.3)

6418.5 (3938.9 to 9532.8)

1.473 (1.460 to 1.487)

  1. MDD, major depressive disorder