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Table 1 Univariate analysis of factors for divorce among all participants

From: Real-world predictors of divorce among outpatients with bipolar disorder: sex differences and clinical implications

Factor

Group

Marital status

Fisher’s exact test

Married (N = 1041)

Divorced (N = 30)

p value

Sex

Female: n (%)

535 (51.4)

15 (50.0)

1.000

Male: n (%)

506 (48.6)

15 (50.0)

 

BMI at baseline (mean (SD))

 

23.62 (4.10)

22.39 (4.00)

0.125

Age at baseline (mean (SD))

 

54.91 (12.31)

46.83 (11.64)

 < 0.001

Age of onset (mean (SD))

 

37.33 (12.35)

32.25 (9.79)

0.031

Bipolar disorder subcategories

Bipolar I disorder: n (%)

355 (34.1)

10 (33.3)

0.433

Bipolar II disorder: n (%)

632 (60.8)

17 (56.7)

 

Unclassifiable: n (%)

53 (5.1)

3 (10.0)

 

Work status at baseline employed

Unemployed: n (%)

239 (23.1)

7 (23.3)

1.000

Employed: n (%)

795 (76.9)

23 (76.7)

 

Educational background

Special support educational school: n (%)

1 (0.1)

0 (0.0)

0.526

Junior high school: n (%)

42 (4.2)

0 (0.0)

 

High school or vocational school: n (%)

441 (43.8)

14 (50.0)

 

Junior college or technical college: n (%)

93 (9.2)

3 (10.7)

 

Master's degree or higher: n (%)

34 (3.4)

2 (7.1)

 

University: n (%)

397 (39.4)

9 (32.1)

 

Mood status at baseline

Depressive state: n (%)

336 (32.4)

13 (43.3)

0.375

Manic/hypomanic state: n (%)

76 (7.3)

2 (6.7)

 

Mixed feature: n (%)

70 (6.7)

3 (10.0)

 

Remission: n (%)

556 (53.6)

12 (40.0)

 

Intelligence quotient; IQ

 < 71: n (%)

7 (0.7)

0 (0.0)

1.000

85–71: n (%)

29 (2.9)

0 (0.0)

 

 > 85: n (%)

981 (96.5)

28 (100.0)

 

Global assessment of functioning; GAF

81–100: n (%)

477 (45.9)

11 (36.7)

0.668

61–80: n (%)

407 (39.1)

15 (50.0)

 

41–60: n (%)

136 (13.1)

4 (13.3)

 

1–40: n (%)

20 (1.9)

0 (0.0)

 

Mood stabilizers prescription

No: n (%)

190 (18.3)

9 (30.0)

0.148

Yes: n (%)

851 (81.7)

21 (70.0)

 

Antipsychotics prescription

No: n (%)

537 (51.6)

13 (43.3)

0.459

Yes: n (%)

504 (48.4)

17 (56.7)

 

Antidepressants prescription

No: n (%)

625 (60.0)

14 (46.7)

0.185

Yes: n (%)

416 (40.0)

16 (53.3)

 

Anxiolytics prescription

No: n (%)

698 (67.1)

16 (53.3)

0.120

Yes: n (%)

343 (32.9)

14 (46.7)

 

Hypnotics prescription

No: n (%)

427 (41.0)

11 (36.7)

0.709

Yes: n (%)

614 (59.0)

19 (63.3)

 

Rapid cycler at baseline

No: n (%)

965 (92.8)

28 (93.3)

1.000

Yes: n (%)

75 (7.2)

2 (6.7)

 

Manic symptoms during 1 year before baseline

No: n (%)

733 (70.5)

23 (76.7)

0.546

Yes: n (%)

307 (29.5)

7 (23.3)

 

Hospitalization during 1 year before baseline

No: n (%)

1019 (97.9)

30 (100.0)

1.000

Yes: n (%)

22 (2.1)

0 (0.0)

 

Personality disorder

No: n (%)

994 (95.6)

25 (83.3)

0.012

Yes: n (%)

46 (4.4)

5 (16.7)

 

Developmental disorder

No: n (%)

999 (96.1)

30 (100.0)

0.625

Yes: n (%)

41 (3.9)

0 (0.0)

 

Physical comrbidity

No: n (%)

715 (68.9)

22 (73.3)

0.692

Yes: n (%)

323 (31.1)

8 (26.7)

 

Substance abuse

No: n (%)

997 (96.1)

29 (96.7)

1.000

Yes: n (%)

41 (3.9)

1 (3.3)

 

Psychotic feature

No: n (%)

992 (95.6)

28 (93.3)

0.395

Yes: n (%)

46 (4.4)

2 (6.7)

 

Suicidal ideation

No: n (%)

974 (93.8)

27 (90.0)

0.429

Yes: n (%)

64 (6.2)

3 (10.0)

 
  1. p < 0.0021 was regarded as significant using Bonferroni’s correction due to multiple testing