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  1. Primary research

    The newer Opioid Agonist Treatment with lower substitutive opiate doses is associated with better toxicology outcome than the older Harm Reduction Treatment

    Charge-free heroin use disorder treatment in Italy follows two main approaches, i.e., harm reduction treatment (HRT) strategy in community low-threshold facilities for drug addiction and opioid agonist treatme...

    Jacopo V. Bizzarri, Valentina Casetti, Livia Sanna, Angelo Giovanni Icro Maremmani, Luca Rovai, Silvia Bacciardi, Daria Piacentino, Andreas Conca and Icro Maremmani

    Annals of General Psychiatry 2016 15:34

    Published on: 25 November 2016

    The Erratum to this article has been published in Annals of General Psychiatry 2017 16:10

  2. Primary research

    Maternal bonding styles in smokers and non-smokers: a comparative study

    Parental bonding has been implicated in smoking behavior, and the quality of maternal bonding (MB) has been associated with poor mental health and substance use. However, little is known about the association ...

    Iren Csala, Monika Elemery, Fruzsina Martinovszky, Peter Dome, Balazs Dome, Gabor Faludi, Imola Sandor, Zsuzsa Gyorffy, Emma Birkas and Judit Lazary

    Annals of General Psychiatry 2016 15:32

    Published on: 11 November 2016

  3. Primary research

    The impact of psychopathological subtypes on retention rate of patients with substance use disorder entering residential therapeutic community treatment

    A specific psychopathology of addiction has been proposed and described using the self-report symptom inventory (SCL-90), leading to a 5-factor aggregation of psychological/psychiatric symptoms: ‘worthlessness...

    Angelo G. I. Maremmani, Pier Paolo Pani, Emanuela Trogu, Federica Vigna-Taglianti, Federica Mathis, Roberto Diecidue, Ursula Kirchmayer, Laura Amato, Joli Ghibaudi, Antonella Camposeragna, Alessio Saponaro, Marina Davoli, Fabrizio Faggiano and Icro Maremmani

    Annals of General Psychiatry 2016 15:29

    Published on: 8 November 2016

  4. Primary research

    Personality traits, gender roles and sexual behaviours of young adult males

    Previous studies have shown that personality characteristics affect sexual functioning. The aim of this exploratory study was to assess and describe the relationship between global personality traits and the s...

    Jacek Kurpisz, Monika Mak, Michał Lew-Starowicz, Krzysztof Nowosielski, Przemysław Bieńkowski, Robert Kowalczyk, Błażej Misiak, Dorota Frydecka and Jerzy Samochowiec

    Annals of General Psychiatry 2016 15:28

    Published on: 21 October 2016

  5. Primary research

    Effect of mirtazapine versus selective serotonin reuptake inhibitors on benzodiazepine use in patients with major depressive disorder: a pragmatic, multicenter, open-label, randomized, active-controlled, 24-week trial

    This study aimed to evaluate whether selecting mirtazapine as the first choice for current depressive episode instead of selective serotonin reuptake inhibitors (SSRIs) reduces benzodiazepine use in patients w...

    Tasuku Hashimoto, Akihiro Shiina, Tadashi Hasegawa, Hiroshi Kimura, Yasunori Oda, Tomihisa Niitsu, Masatomo Ishikawa, Masumi Tachibana, Katsumasa Muneoka, Satoshi Matsuki, Michiko Nakazato and Masaomi Iyo

    Annals of General Psychiatry 2016 15:27

    Published on: 19 October 2016

  6. Primary research

    Regional cortical thinning of the orbitofrontal cortex in medication-naïve female patients with major depressive disorder is not associated with MAOA-uVNTR polymorphism

    Orbitofrontal cortex alterations have been suggested to underlie the impaired mood regulation in depression. MAOA-uVNTR (monoamine oxidase A-upstream variable number of tandem repeats) polymorphism has been repor...

    Eunsoo Won, Sunyoung Choi, June Kang, Min-Soo Lee and Byung-Joo Ham

    Annals of General Psychiatry 2016 15:26

    Published on: 12 October 2016

  7. Primary research

    Analysis of personality traits and their influence on the quality of life of postmenopausal women with regard to genetic factors

    Quality of life can be perceived as a subjective assessment of different aspects of human functioning. Personality is a factor which determines actions taken by individuals and their tendency to perceive reali...

    Daria Schneider-Matyka, Anna Jurczak, Agnieszka Samochowiec, Beata Karakiewicz, Małgorzata Szkup, Anna Grzywacz and Elżbieta Grochans

    Annals of General Psychiatry 2016 15:25

    Published on: 8 September 2016

  8. Primary research

    Multi-regression analysis revealed a relationship between l-serine and methionine, a component of one-carbon metabolism, in the normal control but not in the schizophrenia

    Alterations in one-carbon metabolism (OCM) have been observed in patients with schizophrenia (SZ), but a comprehensive study of OCM has not yet been conducted. A carbon atom is transferred from l-serine to methio...

    Yumiko Takano, Yuji Ozeki, Masae Sekine, Kumiko Fujii, Takashi Watanabe, Hiroaki Okayasu, Takahiro Shinozaki, Akiko Aoki, Kazufumi Akiyama, Hiroshi Homma and Kazutaka Shimoda

    Annals of General Psychiatry 2016 15:23

    Published on: 31 August 2016

  9. Primary research

    A prospective hospital study of alcohol use disorders, comorbid psychiatric conditions and withdrawal prognosis

    The objective of this study was to describe the profile and alcoholic status of a population with alcohol use disorders (AUD) requesting help from a psychiatric hospital to stop drinking, as well as their clin...

    Philippe Nubukpo, Murielle Girard, Jean-Marie Sengelen, Sophie Bonnefond, Aurélien Varnoux, Benoît Marin and Dominique Malauzat

    Annals of General Psychiatry 2016 15:22

    Published on: 31 August 2016

  10. Primary research

    Pharmacotherapy and group cognitive behavioral therapy enhance follow-up treatment duration in gambling disorder patients

    Longer treatment duration is important for the successful treatment of gambling disorder (GD). This retrospective study investigated the factors and interventions that might enhance treatment duration in GD p...

    Sam-Wook Choi, Young-Chul Shin, HyunChul Youn, Se-Won Lim and Juwon Ha

    Annals of General Psychiatry 2016 15:20

    Published on: 12 August 2016

  11. Primary research

    Relationship of suicide rates with climate and economic variables in Europe during 2000–2012

    It is well known that suicidal rates vary considerably among European countries and the reasons for this are unknown, although several theories have been proposed. The effect of economic variables has been ext...

    Konstantinos N. Fountoulakis, Isaia Chatzikosta, Konstantinos Pastiadis, Prodromos Zanis, Wolfram Kawohl, Ad J. F. M. Kerkhof, Alvydas Navickas, Cyril Höschl, Dusica Lecic-Tosevski, Eliot Sorel, Elmars Rancans, Eva Palova, Georg Juckel, Goran Isacsson, Helena Korosec Jagodic, Ileana Botezat-Antonescu…

    Annals of General Psychiatry 2016 15:19

    Published on: 9 August 2016

  12. Primary research

    CT genotype of 5,10-methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism is protector factor of major depressive disorder in the Tunisian population: a case control study

    Major depressive disorder (MDD) is a common psychiatric disorder with considerable mortality. Death from unnatural causes, largely suicidal or quasi-suicidal, has a particularly high risk for the functional di...

    Mohamed Amine Sayadi, Ons Achour, Asma Ezzaher, Ilham Hellara, Asma Omezzine, Wahiba Douki, Ali Bousslama, Lotfi Gaha and Mohamed Fadhel Najjar

    Annals of General Psychiatry 2016 15:18

    Published on: 30 July 2016

  13. Primary research

    Hyperthymic affective temperament and hypertension are independent determinants of serum brain-derived neurotrophic factor level

    Brain-derived neurotrophic factor (BDNF) has neuroprotective, proangiogenic and myogenic effects and, therefore, possibly acts as a psychosomatic mediator. Here, we measured serum BDNF (seBDNF) level in hypert...

    János Nemcsik, Andrea László, Lilla Lénárt, Dániel Eörsi, Péter Torzsa, Beáta Kőrösi, Orsolya Cseprekál, András Tislér, Ádám Tabák, Xenia Gonda, Zoltán Rihmer, Judit Hodrea, Zsófia Nemcsik-Bencze and Andrea Fekete

    Annals of General Psychiatry 2016 15:17

    Published on: 29 July 2016

  14. Primary research

    Development and validation of a stock addiction inventory (SAI)

    Investing in financial markets is promoted and protected by the government as an essential economic activity, but can turn into a gambling addiction problem. Until now, few scales have widely been used to iden...

    HyunChul Youn, Jung-Seok Choi, Dai-Jin Kim and Sam-Wook Choi

    Annals of General Psychiatry 2016 15:16

    Published on: 28 July 2016

  15. Primary research

    Psychotic spectrum symptoms across the lifespan are related to lifetime suicidality among 147 patients with bipolar I or major depressive disorder

    Conflicting evidence exists about the relationship between psychotic symptoms and suicidality in mood disorders. We aimed to investigate the lifetime suicidality and its relationship with dimensions of the psy...

    Camilla Gesi, Claudia Carmassi, Mario Miniati, Antonella Benvenuti, Gabriele Massimetti and Liliana Dell’Osso

    Annals of General Psychiatry 2016 15:15

    Published on: 21 June 2016

  16. Primary research

    Increased arterial stiffness parameters in panic disorder patients in long term treatment period

    The relationship between mental stress and cardiovascular disease has been shown in several studies. Panic disorder (PD) is also associated with cardiovascular disease due to increased risk of myocardial infar...

    Omer Yanartas, Murat Sunbul, Zeynep Senkal, Erdal Durmus, Tarik Kivrak, Nilufer Subasi, Gulhan Karaer, Serhat Ergun, Ibrahim Sari and Kemal Sayar

    Annals of General Psychiatry 2016 15:14

    Published on: 8 June 2016

  17. Primary research

    Psychopathology of addiction: May a SCL-90-based five dimensions structure be applied irrespectively of the involved drug?

    We previously found a five cluster of psychological symptoms in heroin use disorder (HUD) patients: ‘worthlessness-being trapped’, ‘somatic-symptoms’, ‘sensitivity-psychoticism’, ‘panic-anxiety’, and ‘violence...

    Pier Paolo Pani, Angelo G. I. Maremmani, Emanuela Trogu, Federica Vigna-Taglianti, Federica Mathis, Roberto Diecidue, Ursula Kirchmayer, Laura Amato, Joli Ghibaudi, Antonella Camposeragna, Alessio Saponaro, Marina Davoli, Fabrizio Faggiano and Icro Maremmani

    Annals of General Psychiatry 2016 15:13

    Published on: 26 April 2016

  18. Primary research

    Relationship between the lesion location of acute ischemic stroke and early depressive symptoms in Japanese patients

    Approximately one-third of stroke survivors suffer from post-stroke depression (PSD) in the acute or chronic stages. The presence of PSD in the acute stage after stroke is reportedly associated with poor patie...

    Norifumi Metoki, Norio Sugawara, Joji Hagii, Shin Saito, Hiroshi Shiroto, Tetsu Tomita, Minoru Yasujima, Ken Okumura and Norio Yasui-Furukori

    Annals of General Psychiatry 2016 15:12

    Published on: 1 April 2016

  19. Primary research

    Link of dysfunctional attitudes with the negative self-model

    Beck’s cognitive theory postulates that dysfunctional attitudes predisposing to depression are formed by early negative experiences. Meanwhile, Bowlby’s attachment theory contends that distorted working models...

    Koichi Otani, Akihito Suzuki, Yoshihiko Matsumoto and Masanori Enokido

    Annals of General Psychiatry 2016 15:11

    Published on: 15 March 2016

  20. Primary research

    The genetic and environmental structure of the character sub-scales of the temperament and character inventory in adolescence

    The character higher order scales (self-directedness, cooperativeness, and self-transcendence) in the temperament and character inventory are important general measures of health and well-being [Mens Sana Mono...

    Nigel Lester, Danilo Garcia, Sebastian Lundström, Sven Brändström, Maria Råstam, Nóra Kerekes, Thomas Nilsson, C. Robert Cloninger and Henrik Anckarsäter

    Annals of General Psychiatry 2016 15:10

    Published on: 12 March 2016

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