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  1. Case report

    HLA DRB1*03 as a possible common etiology of schizophrenia, Graves’ disease, and type 2 diabetes

    Autoimmune diseases and schizophrenia share many common features. Association studies confirm a shared genetic association in the human leukocyte antigen (HLA) region between schizophrenia and most autoimmune ...

    Aicha Sayeh, Cheker Ben Cheikh, Ali Mardessi, Meriem Mrad, Brahim Nsiri, Abdelaziz Oumaya and Najiba Fekih-Mrissa

    Annals of General Psychiatry 2017 16:7

    Published on: 2 February 2017

  2. Primary research

    Preventing involuntary admissions: special needs for distinct patient groups

    Coercive measures in psychiatry are a controversial topic and raise ethical, legal and clinical issues. Involuntary admission of patients is a long-lasting problem and indicates a problematic pathway to care s...

    Knut Hoffmann, I. S. Haussleiter, F. Illes, J. Jendreyschak, A. Diehl, B. Emons, C. Armgart, A. Schramm and G. Juckel

    Annals of General Psychiatry 2017 16:3

    Published on: 25 January 2017

  3. Primary research

    A pilot study exploring the association of morphological changes with 5-HTTLPR polymorphism in OCD patients

    Clinical and pharmacological studies of obsessive-compulsive disorder (OCD) have suggested that the serotonergic systems are involved in the pathogenesis, while structural imaging studies have found some neuro...

    Shinichi Honda, Tomohiro Nakao, Hiroshi Mitsuyasu, Kayo Okada, Leo Gotoh, Mayumi Tomita, Hirokuni Sanematsu, Keitaro Murayama, Keisuke Ikari, Masumi Kuwano, Takashi Yoshiura, Hiroaki Kawasaki and Shigenobu Kanba

    Annals of General Psychiatry 2017 16:2

    Published on: 17 January 2017

  4. Primary research

    Antidepressive response of inpatients with major depression to adjuvant occupational therapy: a case–control study

    Despite marked costs and limited evidence regarding effectiveness, occupational therapy (OT) is widely applied in psychiatric settings and financed by health insurance companies in European countries. This pil...

    Marc-Andreas Edel, Brian Blackwell, Markus Schaub, Barbara Emons, Tanja Fox, Friederike Tornau, Bernward Vieten, Patrik Roser, Ida Sibylle Haussleiter and Georg Juckel

    Annals of General Psychiatry 2017 16:1

    Published on: 3 January 2017

  5. Primary research

    The association between altered lipid profile and suicide attempt among Tunisian patients with schizophrenia

    There have been many studies on psychiatric disorders, but very little is known about the biology of suicide with schizophrenia. In the present study, we are looking for a possible connection between altered l...

    Rym Mensi, Amal Messaoud, Ahmed Mhallah, Islem Azizi, Walid Haj Salah, Wahiba Douki, Mohamed Fadhel Najjar and Lotfi Gaha

    Annals of General Psychiatry 2016 15:36

    Published on: 16 December 2016

  6. Primary research

    Suicidal ideation and suicide attempts among asthma

    The present study aimed to investigate the mental health status in patients with asthma and assess the effects of asthma on suicidal ideation and attempts using a representative sample from Korea.

    Jae Ho Chung, Sun- Hyun Kim and Yong Won Lee

    Annals of General Psychiatry 2016 15:35

    Published on: 29 November 2016

    The Erratum to this article has been published in Annals of General Psychiatry 2017 16:4

  7. Primary research

    The newer Opioid Agonist Treatment with lower substitutive opiate doses is associated with better toxicology outcome than the older Harm Reduction Treatment

    Charge-free heroin use disorder treatment in Italy follows two main approaches, i.e., harm reduction treatment (HRT) strategy in community low-threshold facilities for drug addiction and opioid agonist treatme...

    Jacopo V. Bizzarri, Valentina Casetti, Livia Sanna, Angelo Giovanni Icro Maremmani, Luca Rovai, Silvia Bacciardi, Daria Piacentino, Andreas Conca and Icro Maremmani

    Annals of General Psychiatry 2016 15:34

    Published on: 25 November 2016

    The Erratum to this article has been published in Annals of General Psychiatry 2017 16:10

  8. Primary research

    Maternal bonding styles in smokers and non-smokers: a comparative study

    Parental bonding has been implicated in smoking behavior, and the quality of maternal bonding (MB) has been associated with poor mental health and substance use. However, little is known about the association ...

    Iren Csala, Monika Elemery, Fruzsina Martinovszky, Peter Dome, Balazs Dome, Gabor Faludi, Imola Sandor, Zsuzsa Gyorffy, Emma Birkas and Judit Lazary

    Annals of General Psychiatry 2016 15:32

    Published on: 11 November 2016

  9. Primary research

    The impact of psychopathological subtypes on retention rate of patients with substance use disorder entering residential therapeutic community treatment

    A specific psychopathology of addiction has been proposed and described using the self-report symptom inventory (SCL-90), leading to a 5-factor aggregation of psychological/psychiatric symptoms: ‘worthlessness...

    Angelo G. I. Maremmani, Pier Paolo Pani, Emanuela Trogu, Federica Vigna-Taglianti, Federica Mathis, Roberto Diecidue, Ursula Kirchmayer, Laura Amato, Joli Ghibaudi, Antonella Camposeragna, Alessio Saponaro, Marina Davoli, Fabrizio Faggiano and Icro Maremmani

    Annals of General Psychiatry 2016 15:29

    Published on: 8 November 2016

  10. Primary research

    Personality traits, gender roles and sexual behaviours of young adult males

    Previous studies have shown that personality characteristics affect sexual functioning. The aim of this exploratory study was to assess and describe the relationship between global personality traits and the s...

    Jacek Kurpisz, Monika Mak, Michał Lew-Starowicz, Krzysztof Nowosielski, Przemysław Bieńkowski, Robert Kowalczyk, Błażej Misiak, Dorota Frydecka and Jerzy Samochowiec

    Annals of General Psychiatry 2016 15:28

    Published on: 21 October 2016

  11. Primary research

    Effect of mirtazapine versus selective serotonin reuptake inhibitors on benzodiazepine use in patients with major depressive disorder: a pragmatic, multicenter, open-label, randomized, active-controlled, 24-week trial

    This study aimed to evaluate whether selecting mirtazapine as the first choice for current depressive episode instead of selective serotonin reuptake inhibitors (SSRIs) reduces benzodiazepine use in patients w...

    Tasuku Hashimoto, Akihiro Shiina, Tadashi Hasegawa, Hiroshi Kimura, Yasunori Oda, Tomihisa Niitsu, Masatomo Ishikawa, Masumi Tachibana, Katsumasa Muneoka, Satoshi Matsuki, Michiko Nakazato and Masaomi Iyo

    Annals of General Psychiatry 2016 15:27

    Published on: 19 October 2016

  12. Primary research

    Regional cortical thinning of the orbitofrontal cortex in medication-naïve female patients with major depressive disorder is not associated with MAOA-uVNTR polymorphism

    Orbitofrontal cortex alterations have been suggested to underlie the impaired mood regulation in depression. MAOA-uVNTR (monoamine oxidase A-upstream variable number of tandem repeats) polymorphism has been repor...

    Eunsoo Won, Sunyoung Choi, June Kang, Min-Soo Lee and Byung-Joo Ham

    Annals of General Psychiatry 2016 15:26

    Published on: 12 October 2016

  13. Primary research

    Analysis of personality traits and their influence on the quality of life of postmenopausal women with regard to genetic factors

    Quality of life can be perceived as a subjective assessment of different aspects of human functioning. Personality is a factor which determines actions taken by individuals and their tendency to perceive reali...

    Daria Schneider-Matyka, Anna Jurczak, Agnieszka Samochowiec, Beata Karakiewicz, Małgorzata Szkup, Anna Grzywacz and Elżbieta Grochans

    Annals of General Psychiatry 2016 15:25

    Published on: 8 September 2016

  14. Primary research

    Multi-regression analysis revealed a relationship between l-serine and methionine, a component of one-carbon metabolism, in the normal control but not in the schizophrenia

    Alterations in one-carbon metabolism (OCM) have been observed in patients with schizophrenia (SZ), but a comprehensive study of OCM has not yet been conducted. A carbon atom is transferred from l-serine to methio...

    Yumiko Takano, Yuji Ozeki, Masae Sekine, Kumiko Fujii, Takashi Watanabe, Hiroaki Okayasu, Takahiro Shinozaki, Akiko Aoki, Kazufumi Akiyama, Hiroshi Homma and Kazutaka Shimoda

    Annals of General Psychiatry 2016 15:23

    Published on: 31 August 2016

  15. Primary research

    A prospective hospital study of alcohol use disorders, comorbid psychiatric conditions and withdrawal prognosis

    The objective of this study was to describe the profile and alcoholic status of a population with alcohol use disorders (AUD) requesting help from a psychiatric hospital to stop drinking, as well as their clin...

    Philippe Nubukpo, Murielle Girard, Jean-Marie Sengelen, Sophie Bonnefond, Aurélien Varnoux, Benoît Marin and Dominique Malauzat

    Annals of General Psychiatry 2016 15:22

    Published on: 31 August 2016

  16. Primary research

    Pharmacotherapy and group cognitive behavioral therapy enhance follow-up treatment duration in gambling disorder patients

    Longer treatment duration is important for the successful treatment of gambling disorder (GD). This retrospective study investigated the factors and interventions that might enhance treatment duration in GD p...

    Sam-Wook Choi, Young-Chul Shin, HyunChul Youn, Se-Won Lim and Juwon Ha

    Annals of General Psychiatry 2016 15:20

    Published on: 12 August 2016

  17. Primary research

    Relationship of suicide rates with climate and economic variables in Europe during 2000–2012

    It is well known that suicidal rates vary considerably among European countries and the reasons for this are unknown, although several theories have been proposed. The effect of economic variables has been ext...

    Konstantinos N. Fountoulakis, Isaia Chatzikosta, Konstantinos Pastiadis, Prodromos Zanis, Wolfram Kawohl, Ad J. F. M. Kerkhof, Alvydas Navickas, Cyril Höschl, Dusica Lecic-Tosevski, Eliot Sorel, Elmars Rancans, Eva Palova, Georg Juckel, Goran Isacsson, Helena Korosec Jagodic, Ileana Botezat-Antonescu…

    Annals of General Psychiatry 2016 15:19

    Published on: 9 August 2016

  18. Primary research

    CT genotype of 5,10-methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism is protector factor of major depressive disorder in the Tunisian population: a case control study

    Major depressive disorder (MDD) is a common psychiatric disorder with considerable mortality. Death from unnatural causes, largely suicidal or quasi-suicidal, has a particularly high risk for the functional di...

    Mohamed Amine Sayadi, Ons Achour, Asma Ezzaher, Ilham Hellara, Asma Omezzine, Wahiba Douki, Ali Bousslama, Lotfi Gaha and Mohamed Fadhel Najjar

    Annals of General Psychiatry 2016 15:18

    Published on: 30 July 2016

  19. Primary research

    Hyperthymic affective temperament and hypertension are independent determinants of serum brain-derived neurotrophic factor level

    Brain-derived neurotrophic factor (BDNF) has neuroprotective, proangiogenic and myogenic effects and, therefore, possibly acts as a psychosomatic mediator. Here, we measured serum BDNF (seBDNF) level in hypert...

    János Nemcsik, Andrea László, Lilla Lénárt, Dániel Eörsi, Péter Torzsa, Beáta Kőrösi, Orsolya Cseprekál, András Tislér, Ádám Tabák, Xenia Gonda, Zoltán Rihmer, Judit Hodrea, Zsófia Nemcsik-Bencze and Andrea Fekete

    Annals of General Psychiatry 2016 15:17

    Published on: 29 July 2016

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