Skip to main content

Table 3 Complement levels in anorexia patients and controls

From: Complement C3 serum levels in anorexia nervosa: a potential biomarker for the severity of disease?

Complement activation adjusted for protein

Healthy controls

Anorexia nervosa patients

(admission laboratory test results)

P valuea

Patient numbers, n

17

14

 

CH50, U Eq/ml

1.8 (1.4-2.2)

1.6 (0.9-2.0)

0.64

C3, ng/mg protein

11.4 (8.9-13.7)

3.7 (2.5-4.9)

<0.001

C3a, ng/mg protein

1,985 (1,817-2,488)

1,799 (1,295-3,752)

0.83

C5a, pg/mg protein

437 (412-477)

469 (439-537)

0.10

sC5b-9, ng/mg protein

1.9 (0.7-4.6)

2.8 (2.0-6.8)

0.22

  1. aConcentrations were assessed in serum samples. Statistical analysis compares concentrations between cohorts using Wilcoxon rank sum test. Data are expressed as median (interquartile range).
  2. bLaboratory samples were unavailable for one patient for C5a and CH50, nine controls for CH50, and two controls for sC5b-9.
  3. CH50 = 50% hemolytic complement activity.