Validation of a specific measure to assess health-related quality of life in patients with schizophrenia and bipolar disorder: the 'Tolerability and quality of life' (TOOL) questionnaire

Table 4 Spearman rank correlations (r_s) between Spanish 'TOlerability and quality Of Life' (TOOL) and generic measures of health-related quality of life (HRQoL)

r_s	Function capabilities	Fatigue-weakness	Weight gain	Stiffness-tremor	Physical restlessness	Sexual dysfunction	Dizziness-nausea	EQ-5 D (unweighted)	SF-6 D (unweighted)
Worry-upset	0.501**	0.495**	0.204**	0.230**	0.416**	0.225**	0.121	-0.532**	-0.537**
Function capabilities		0.471**	0.211**	0.207**	0.375**	0.306**	0.156*	-0.591**	-0.642**
Fatigue-weakness			0.222**	0.253**	0.409**	0.291**	0.279**	-0.557**	-0.565**
Weight gain				0.213**	0.080	0.191**	0.082	-0.225**	-0.238**
Stiffness-tremor					0.243**	0.111	0.187**	-0.328**	-0.277**
Physical restlessness						0.264**	0.090	-0.422**	-0.334**
Sexual dysfunction							0.164**	-0.406**	-0.382**
Dizziness-nausea								-0.224**	-0.158*
Spanish TOOL	-	-	-	-	-	-	-	-0.720**	-0.678**
Spanish TOOL (schizophrenia)	-	-	-	-	-	-	-	-0.716**	-0.645**
Spanish TOOL (bipolar disorder)	-	-	-	-	-	-	-	-0.720**	-0.724**

*Correlation is significant at the 0.05 level (two tailed); **correlation is significant at the 0.01 level (two tailed).

ISSN: 1744-859X