Disability and health-related quality of life in outpatients with generalised anxiety disorder treated in psychiatric clinics: is there still room for improvement?

Table 2 Assessing of clinical impact in two patients groups (newly diagnosed/follow-up), according to different scales used

Scale	Characteristics	Total (n = 790, 100.0%)	Newly diagnosed (n = 124, 15.7%)	Follow-up (n = 666, 84.3%)	P value
HAM-A	Intensity of the categorised anxiety				< 0.001
	Intense (> 24)	45.2%	56.9%	43.0%
	Moderate (16-24)	33.8%	38.2%	32.9%
	Mild (10-15)	11.3%	4.1%	12.6%
	Without anxiety (0-9)	9.8%	0.8%	11.4%
	Subscale for psychic anxiety	12.3 (4.9)	14.2 (3.6)	12.0 (5.0)	< 0.001
	Subscale for somatic anxiety	10.8 (5.2)	12.6 (4.5)	10.4 (5.2)	< 0.001
	Total scoring	23.1 (9.4)	26.8 (7.3)	22.4 (9.6)	< 0.001
CGI	Psychiatrist	3.8 (1.1)	4.2 (0.8)	3.7 (1.1)	< 0.001
	Patient	4.2 (1.3)	4.7 (1.0)	4.1 (1.3)	< 0.001
SDI	Incapacity for work	5.3 (2.7)	5.7 (2.4)	5.3 (2.8)	NS
	Incapacity for social life	5.6 (2.6)	5.9 (2.2)	5.5 (2.6)	NS
	Incapacity for family relationships	5.1 (2.5)	5.6 (2.2)	5.1 (2.6)	NS
	General incapacity (work-social-family)	16.0 (7.0)	17.1 (6.0)	15.9 (7.2)	NS
	Perceived stress	5.3 (2.3)	5.7 (2.1)	5.2 (2.4)	0.032
	Perceived social support	56.1 (26.1)	59.0 (23.9)	55.7 (26.4)	NS
SF-36	Physical health summary index	43.3 (9.0)	43.3 (8.9)	43.3 (9.1)	NS
	Z Punctuation physical health summary index	-0.7 (0.9)	-0.7 (0.9)	-0.7 (0.9)	NS
	Mental health summary index	30.0 (11.4)	25.4 (8.5)	30.8 (11.7)	< 0.001
	Z Punctuation mental health summary index	-2.0 (1.1)	-2.5 (0.8)	-1.9 (1.2)	< 0.001

Values are expressed as mean (SD) or percentages.
CGI = clinical global impression of disease; HAM-A = Hamilton Anxiety scale (HAM-A); NS = not significant SDS = Sheeham Disability Scale (SDS); SF-36 = 36-item short-form health-related quality of life questionnaire.