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Table 6 Serum cytokine concentrations in 41 perimenopausal women with depression subdivided into five groups according to the presence and severity of hot flashes (Menopause Rating Scale)

From: The role of cytokines and hot flashes in perimenopausal depression

Cytokine

Hot flashes

P value, Kruskal-Wallis

 

Without, (n = 2)

Mild, (n = 7)

Moderate, (n = 6)

Severe, (n = 17)

s Very severe, (n = 9)

 

TNFα

0.00 (true zero)

4.61 (1.84 to 7.35)

7.35

8.99 (4.65 to 14.30)

13.19 (7.12 to 21.90)

0.583, NS

IL-6

0.00 (true zero)

1.44 (1.44 to 1.44)

1.13

2.50 (1.44 to 4.67)

2.11 (1.50 to 2.95)

0.719, NS

IL-10

0.00 (true zero)

0.00 (true zero)

4.54

4.96 (3.10 to 10.20)

6.83 (3.44 to 12.00)

0.745, NS

  1. The results of cytokines are expressed as medians (10% to 90%). Unit of serum cytokine concentration is pg/ml.
  2. IL = interleukin; NS = not significant; TNF = tumor necrosis factor.