Figure 1
From: How to diagnose the 22q11.2 deletion syndrome in patients with schizophrenia: a case report
Features of a 48-year-old woman with the 22q11.2 deletion. (a) Past history of an operation for cleft palate. (b) Mild dysmorphic facial features, including a low anterior hairline, swollen eyelids, malar flatness, nose with a bulbous nasal tip, hypoplastic nasal alae and a square and flat nasal root, small mouth, and a thin upper lip. (c) Basal ganglia calcification due to hypocalcemia. (d) Fluorescence in situ hybridization; red and green regions were detected by TUPLE1 (22q11.2) and ARSA (22q13.3) probes, respectively. The arrow and arrowhead indicate expected red and green regions, respectively. One chromosome 22 with the deletion of TUPLE1 (22q11.2) was detected.