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Table 2 Reasons for switching antipsychotic treatment

From: Reasons and clinical outcomes of antipsychotic treatment switch in outpatients with schizophrenia in real-life clinical settings: the ETOS observational study

Reason Number Percent
Lack of efficacy
 Alone 199 35.0
 In combination with lack of tolerability 50 8.8
 Total 249 43.8
Lack of tolerability
 Alone 319 56.2
 In combination with lack of efficacy 50 8.8
 Total 369 65.0
Lack of tolerability, analytically (n = 369)*
 Weight gain 149 40.4
 Extrapyramidal symptoms 111 30.1
 Lack of tolerance 42 11.4
 Hyperprolactinaemia 39 10.6
 Hyperlipidaemia and/or glucose increase 24 6.5
 Stress/insomnia/anxiety/akathisia 16 4.3
 Sleepiness/drowsiness 12 3.2
 Gynecological dysfunctions 6 1.6
 Sexual disorders 6 1.6
 Other adverse events 10 2.7
  1. Asterisk ‘*’ denotes more than one of these reasons may have been selected.