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Table 2 Reasons for switching antipsychotic treatment

From: Reasons and clinical outcomes of antipsychotic treatment switch in outpatients with schizophrenia in real-life clinical settings: the ETOS observational study

Reason

Number

Percent

Lack of efficacy

 Alone

199

35.0

 In combination with lack of tolerability

50

8.8

 Total

249

43.8

Lack of tolerability

 Alone

319

56.2

 In combination with lack of efficacy

50

8.8

 Total

369

65.0

Lack of tolerability, analytically (n = 369)*

 Weight gain

149

40.4

 Extrapyramidal symptoms

111

30.1

 Lack of tolerance

42

11.4

 Hyperprolactinaemia

39

10.6

 Hyperlipidaemia and/or glucose increase

24

6.5

 Stress/insomnia/anxiety/akathisia

16

4.3

 Sleepiness/drowsiness

12

3.2

 Gynecological dysfunctions

6

1.6

 Sexual disorders

6

1.6

 Other adverse events

10

2.7

  1. Asterisk ‘*’ denotes more than one of these reasons may have been selected.