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Table 4 Dosing considerations when switching non-acute patients with schizophrenia from other oral atypical antipsychotics to paliperidone ER

From: Dosing and switching of paliperidone ER in patients with schizophrenia: recommendations for clinical practice

Prior oral antipsychotic medication

Daily dose of prior antipsychotic (mg)

Daily dose of paliperidone ER (mg)

Olanzapine

10a

6a

14.2b[56]

7.2c[63]

Risperidone

5a

6a

4.3b[56]

7.1 [64]

Quetiapine

400a

6a

485.3b[56]

6.8c[65]

Aripiprazole

15a

6a

19.4b[56]

6.8 [66]

  1. aWHO DDD (mg) [67]; blast used mean daily dose; cdoses of up to 9 mg/day may be required depending on the individual patient circumstances [68]. WHO, World Health Organization; DDD, defined daily dose; ER, extended release.