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Table 2 Frequency distribution of second-step intervention by initial monotherapy SSRI treatment

From: What happens next?: a claims database study of second-line pharmacotherapy in patients with major depressive disorder (MDD) who initiate selective serotonin reuptake inhibitor (SSRI) treatment

Second-step intervention

Initial monotherapy treatment

Citalopram hydrochloride

Sertraline hydrochloride

Escitalopram oxalate

Fluoxetine hydrochloride

Paroxetine hydrochloride/mesylate

Fluvoxamine

Total

N = 1,510

N = 1,380

N = 936

N = 899

N = 272

N = 15

N = 5,012

n(%)

n(%)

n(%)

n(%)

n(%)

n(%)

n(%)

Continued

469 (31.1)

425 (30.8)

295 (31.5)

286 (31.8)

66 (24.3)

4 (26.7)

1,545 (30.8)

Discontinued

266 (17.6)

207 (15.0)

137 (14.6)

145 (16.1)

43 (15.9)

4 (26.7)

802 (16.0)

Switch

254 (16.8)

206 (14.9)

138 (14.7)

120 (13.3)

48 (17.6)

5 (33.3)

771 (15.4)

Add-on

521 (34.5)

542 (39.3)

366 (39.1)

348 (38.7)

115 (42.3)

2 (13.3)

1,894 (37.8)