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Table 2 Frequency distribution of second-step intervention by initial monotherapy SSRI treatment

From: What happens next?: a claims database study of second-line pharmacotherapy in patients with major depressive disorder (MDD) who initiate selective serotonin reuptake inhibitor (SSRI) treatment

Second-step intervention Initial monotherapy treatment
Citalopram hydrochloride Sertraline hydrochloride Escitalopram oxalate Fluoxetine hydrochloride Paroxetine hydrochloride/mesylate Fluvoxamine Total
N = 1,510 N = 1,380 N = 936 N = 899 N = 272 N = 15 N = 5,012
n(%) n(%) n(%) n(%) n(%) n(%) n(%)
Continued 469 (31.1) 425 (30.8) 295 (31.5) 286 (31.8) 66 (24.3) 4 (26.7) 1,545 (30.8)
Discontinued 266 (17.6) 207 (15.0) 137 (14.6) 145 (16.1) 43 (15.9) 4 (26.7) 802 (16.0)
Switch 254 (16.8) 206 (14.9) 138 (14.7) 120 (13.3) 48 (17.6) 5 (33.3) 771 (15.4)
Add-on 521 (34.5) 542 (39.3) 366 (39.1) 348 (38.7) 115 (42.3) 2 (13.3) 1,894 (37.8)