From: QTc and psychopharmacs: are there any differences between monotherapy and polytherapy
Group 1 (N = 32) | Group 2 (N = 29) | ||
---|---|---|---|
Characteristic | Patients in monotherapy | Patients in polytherapy | *p |
QTc I, mean ± SD (ms) | 439 ± 22 | 439 ± 22 | 0.953 |
QTc II, mean ± SD (ms) | 439 ± 24 | 440 ± 20 | 0.878 |
***p | 0.989 | 0.812 | |
QTc prolongation, mean ± SD (ms) | 8 ± 17 | 9 ± 19 | 0.840 |
**p | |||
QTc I > 450 ms, N (%) | 12 (37.5) | 10 (34.5) | 1.000 |
QTc II > 450 ms, N (%) | 10 (31.3) | 9 (31.0) | 1.000 |
QTc I 451–470 ms, N (%) | 11 (34.4) | 8 (27.6) | 0.593 |
QTc II 451–470 ms, N (%) | 6 (18.7) | 7 (24.1) | 0.757 |
QTc I > 470 ms, N (%) | 1 (3.1) | 2 (6.9) | 0.600 |
QTc II > 470 ms, N (%) | 4 (12.5) | 2 (6.9) | 0.674 |
QTc II – QTc I > 30 ms, N (%) | 3 (9.4) | 3 (10.3) | 1.000 |