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Table 3 Characteristics of QTc interval

From: QTc and psychopharmacs: are there any differences between monotherapy and polytherapy

 

Group 1 (N = 32)

Group 2 (N = 29)

 

Characteristic

Patients in monotherapy

Patients in polytherapy

*p

QTc I, mean ± SD (ms)

439 ± 22

439 ± 22

0.953

QTc II, mean ± SD (ms)

439 ± 24

440 ± 20

0.878

***p

0.989

0.812

 

QTc prolongation, mean ± SD (ms)

8 ± 17

9 ± 19

0.840

   

**p

QTc I > 450 ms, N (%)

12 (37.5)

10 (34.5)

1.000

QTc II > 450 ms, N (%)

10 (31.3)

9 (31.0)

1.000

QTc I 451–470 ms, N (%)

11 (34.4)

8 (27.6)

0.593

QTc II 451–470 ms, N (%)

6 (18.7)

7 (24.1)

0.757

QTc I > 470 ms, N (%)

1 (3.1)

2 (6.9)

0.600

QTc II > 470 ms, N (%)

4 (12.5)

2 (6.9)

0.674

QTc II – QTc I > 30 ms, N (%)

3 (9.4)

3 (10.3)

1.000

  1. *p – 2-tailed unpaired t test; **p – 2-tailed Fisher Exact test; ***p – 2-tailed paired t test; QTc I – baseline QTc; QTc II – QTc after two weeks of treatment