Skip to main content

Advertisement

Table 3 Characteristics of QTc interval

From: QTc and psychopharmacs: are there any differences between monotherapy and polytherapy

  Group 1 (N = 32) Group 2 (N = 29)  
Characteristic Patients in monotherapy Patients in polytherapy *p
QTc I, mean ± SD (ms) 439 ± 22 439 ± 22 0.953
QTc II, mean ± SD (ms) 439 ± 24 440 ± 20 0.878
***p 0.989 0.812  
QTc prolongation, mean ± SD (ms) 8 ± 17 9 ± 19 0.840
    **p
QTc I > 450 ms, N (%) 12 (37.5) 10 (34.5) 1.000
QTc II > 450 ms, N (%) 10 (31.3) 9 (31.0) 1.000
QTc I 451–470 ms, N (%) 11 (34.4) 8 (27.6) 0.593
QTc II 451–470 ms, N (%) 6 (18.7) 7 (24.1) 0.757
QTc I > 470 ms, N (%) 1 (3.1) 2 (6.9) 0.600
QTc II > 470 ms, N (%) 4 (12.5) 2 (6.9) 0.674
QTc II – QTc I > 30 ms, N (%) 3 (9.4) 3 (10.3) 1.000
  1. *p – 2-tailed unpaired t test; **p – 2-tailed Fisher Exact test; ***p – 2-tailed paired t test; QTc I – baseline QTc; QTc II – QTc after two weeks of treatment