PANSS, mean ± SD | Baseline (N = 67) | Week 52 (n = 31) | LOCF Endpoint (N = 67) |
---|---|---|---|
Total | 65.4 ± 13.5 | 57.5 ± 12.7 | 61.7 ± 17.9 |
 |  | P < .0001 | P = .087 |
Positive symptoms | 18.1 ± 5.3 | 15.6 ± 4.5 | 17.3 ± 6.2 |
 |  | P < .0001 | P = .233 |
Negative symptoms | 17.4 ± 5.4 | 16.0 ± 4.4 | 16.1 ± 5.4 |
 |  | P = .007 | P = .071 |
Anxiety/depression | 9.1 ± 3.0 | 7.3 ± 2.7 | 8.5 ± 3.7 |
 |  | P = .002 | P = .133 |
Disorganized thought | 14.4 ± 4.1 | 13.4 ± 3.8 | 13.9 ± 4.2 |
 |  | P = .001 | P = .337 |
Uncontrolled hostility/excitement | 6.3 ± 2.4 | 5.3 ± 1.7 | 5.9 ± 2.4 |
 |  | P = .001 | P = .278 |