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Table 4 Incidence rate of both clinically significant weight gain and extrapyramidal symptoms (EPS) on patients with antipsychotic treatment

From: Costs and effects of paliperidone extended release compared with alternative oral antipsychotic agents in patients with schizophrenia in Greece: A cost effectiveness study

 

% Patients experiencing clinically significant weight gain

Sources

% Patients experiencing EPS

Sources

Paliperidone ER

3.3

Invega PI, Janssen-Cilag International NV Turnhoutseweg 30 BE-2340 Beerse Belgium

9.0%

[15]

[21]

[22]

[23]

Risperidone

9.0

Risperdal PI, Janssen-Cilag Pharmaceutical SACI, Eirinis Avenue 56, 15121, Pefki, Athens, Greece

9.0%

[15]

Olanzapine

26.0

Zyprexa PI, Eli Lilly Nederland B.V., Grootslag 1–5, NL-3991 RA Houten, The Netherlands.

7.0%

[15]

Quetiapine

17.0

Seroquel PI, AstraZeneca Pharmaceuticals LP, Wilmington, DE 19850, USA

3.0%

[15]

Ziprasidone

6.0

Geodon PI, Pfizer Hellas, Ltd, Mesogeion Avenue 243, 15451 Athens, Greece

8.0%

[15]

Aripiprazole

5.0

Abilify PI, Otsuka Pharmaceutical Europe Ltd Hunton House Highbridge Business Park Oxford Road Uxbridge, Middlesex UB8 1HU United Kingdom

8.0%

Assumed equal to ziprasidone