Skip to main content

Table 1 Clinical characteristics of panic disorder patients with and without comorbid bipolar disorder

From: The clinical-familial correlates and naturalistic outcome of panic-disorder-agoraphobia with and without lifetime bipolar II comorbidity

  PD (n = 274) PD+BD (n = 52) F/chi-square p Value
Age, mean (SD) 36.7 (11.5) 35.1 (11.6) -0.9 NS
Sex, female, n (%) 191 (69.7) 31 (59.6) 2.0 NS
Agoraphobia, n (%) 219 (79.9) 44 (84.6) 0.06 NS
First degree family history, n (%):     
Mood disorders 83 (30.3) 23 (44.2) 3.9 0.05
Substance abuse 10 (3.7) 3 (5.8) 0.5 NS
Panic-agoraphobic disorder 110 (40.1) 33 (63.5) 9.6 0.002
Age at onset, mean (SD) 29.9 (10.5) 26.0 (11.0) -2.5 NS
Length of illness in months, mean (SD) 87.2 (128.4) 117.4 (159.4) 1.5 NS
Life-up scores at baseline, mean (SD):     
Panic disorder 3.4 (1.0) 3.2 (0.8) -0.9 NS
Agoraphobia 3.0 (1.2) 3.0 (1.0) 0.2 NS
General adjustment (GAS) 69.8 (11.1) 68.3 (9.8) -0.9 NS
Lifetime comorbidity, n (%):     
Major depression 91 (33.2) -   
Generalized anxiety 46 (16.8) 12 (23.1) 1.2 NS
Social phobia 21 (7.7) 9 (17.3) 4.9 0.03
Obsessive-compulsive 20 (7.3) 11 (21.1) 9.7 0.002.
Alcohol-related disorders 16 (5.8) 9 (17.3) 8.1 0.004.
Separation anxiety 85 (31.0) 24 (46.1) 4.5 0.03
Personality disorders, n (%):     
Avoidant 64 (23.4) 16 (30.8) 1.3 NS
Dependent 37 (13.5) 7 (13.5) 0.000 NS
  1. BP, bipolar disorder; GAS, Global Adjustment Score; NS, not significant; PD, panic disorder.