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Table 4 Effect of bupropion HCl 120 mg/kg intraperitoneal infusion times on the mean ± SD duration of bupropion HCl-induced convulsions in mice

From: Effect of increasing intraperitoneal infusion rates on bupropion hydrochloride-induced seizures in mice

Group* Intraperitoneal (IP) infusion time (min) Mean ± SD duration of convulsions
   Short
(0 to 10 s)
Medium
(11 to 30 s)
Long
(= 31 s)
1 0 (bolus) 11.2 ± 15.6 2.6 ± 3.9 1.6 ± 4.4
2 15 19.9 ± 31.4 4.8 ± 8.0 2.3 ± 3.3
3 30 12.2 ± 15.7 2.5 ± 4.1 1.4 ± 4.1
4 60 12.0 ± 17.7 3.8 ± 7.1 1.0 ± 1.7
5 90 0 0 0
6 120 3.1 ± 9.5 0.2 ± 0.6 0.1 ± 0.3
7 240 0 0 0
  1. *Number of mice was 10 for each group, except group 5 that had 9 mice.