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Table 4 Number of cases of suicide, attempted suicide and suicide ideation associated with acne medications.

From: Isotretinoin and psychopathology: a review

Acne medication Period Suicide Suicide attempt Suicide ideation Total Estimated patient exposure Adverse drug reactions per million
Dianette 1980 to 1998 - 3 - 3   
Doxycycline 1965 to 1998 - 0 - 0   
Minocycline 1971 to 1998 - 2 - 2   
Oxytetracycline 1965 to 1998 - 0 - 0   
Tetracycline 1964 to 1998 - 3 - 3   
Total combined   - 8 - 8 300 million 0.03
Roaccutane 1982 to 1998 47 67 56 170 6 million 28.34
  1. Source: World Health Organization, 1998