Treatment of psychotic symptoms in bipolar disorder with aripiprazole monotherapy: a meta-analysis

Table 5 Effect sizes for Positive and Negative Syndrome Scale (PANSS) total and subscales

	PANSS total		PANSS-positive		PANSS-negative		PANSS-cognitive		PANSS-hostility
	d	95% CI	d	95% CI	d	95% CI	d	95% CI	d	95% CI
Aripiprazole vs placebo
CN138-009	-		-		-		-		-
CN138-074	0.26	0.02 to 0.50	-		-		-		-
CN138-135	0.27	0.05 to 0.49	-		-		0.23	0.01- to 0.45	0.27	0.05 to 0.49
CN138-162	0.28	0.05 to 0.50	0.28	0.05 to 0.51	0.12	-0.11 to 0.34	0.17	-0.05 to 0.40	0.21	-0.01 to 0.44
CN138-007	-0.02	-0.23 to 0.19	-		-		-		-
CN138-008	-		-		-		-		-
Pooled mean	0.14	0.03 to 0.25	0.28	0.05 to 0.51	0.12	-0.11 to 0.34	0.20	0.04 to 0.36	0.24	0.08 to 0.39
Hunter-Schmidt d	0.18	0.176 to 0.184	-		-		0.20	-	0.24	-
Comparator vs placebo
CN138-135	0.12	-0.10 to 0.34	-		-		0.15	-0.07 to 0.37	0.17	-0.05 to 0.39
CN138-162	0.33	0.10 to 0.55	0.36	0.14 to 0.58	0.08	-0.14 to 0.30	0.19	-0.03 to 0.42	0.27	0.05 to 0.49
Pooled mean	0.23	0.10 to 0.36	0.36	0.14 to 0.58	0.08	-0.14 to 0.30	0.16	0.01 to 0.32	0.23	0.07 to 0.38

ISSN: 1744-859X