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Table 2 Comparisons of the demographic and clinical characteristics of subjects belonging to the schizophrenia (SZ) with and without pre-onset cannabis use disorder (pre-onset CUD)

From: A clinical comparison of schizophrenia with and without pre-onset cannabis use disorder: a retrospective cohort study using categorical and dimensional approaches

  Total sample SZ with no pre-onset CUD SZ with pre-onset CUD p
Number of subjects 171 140 31
Male [n (%)] 114 (67.1%) 84 (60.4%) 30 (96.8%) <0.001
Mean age at assessment [years (SD)] 34.0 (11.7) 35.4 (12.1) 27.6 (6.8) 0.001
Mean age at onset [years (SD)] 23.7 (7.9) 24.4 (8.5) 20.9 (3.4) 0.027
Mean age at cannabis use onset [years (SD)] 18.3 (3.7)
Mean duration of the illness [years (SD)] 11.5 (11.1) 12.6 (11.7) 6.7 (6.7) 0.007
Mean number of hospital admissions/illness duration 0.6 (0.7) 0.6 (0.8) 0.6 (0.4) 0.82
Personal history of suicide attempts [n (%)] 75 (45.5%) 65 (47.8%) 10 (34.5%) 0.19
Family history of schizophrenia [n (%)] 16 (10.2%) 12 (9.4%) 4 (13.3%) 0.53
Family history of mood disorders [n (%)] 66 (44.0%) 56 (46.3%) 10 (34.5%) 0.25
Family history of suicide attempts [n (%)] 26 (17.6%) 23 (19.3%) 3 (10.3%) 0.25
  1. Significant p values after Bonferroni correction (threshold p < 0.004) are presented in italics
  2. SD standard deviation, n number