Table 1 Demographic, laboratory, hemodynamic, and arterial stiffness parameters; subjects’ questionnaire scores

N (male:female)

32 (12:20)

151 (58:93)

Age [year]

61.1 (55.9–70.5)

63.7 (57–71)

Duration of hypertension [year]

–

11 (5–18)

Diabetes [n (%)]

–

38 (25.2)

Cardiovascular disease [n (%)]

–

21 (13.9)

Current smoker [n (%)]

3 (9.4)

22 (14.6)

Body height [cm]

168.8 ± 8.6

166.8 ± 8.6

Body weight [kg]

72.4 ± 12.1

79.7 ± 14*

BMI [kg/m²]

24.5 ± 5.4

28.6 ± 4.5*

Platelet count [G/l]

239.6 (215–277)

257 (209.7–303.2)

Glucose [mmol/l]

5.36 (4.88–5.81)

6.15 (5.11–6.7)*

GFR-EPI [ml/min/1.73 m²]

79.7 (69.5–82.2)

77.9 (67–90)

Uric acid [µmol/l]

313.7 ± 11.6

318.4 ± 6.3

Cholesterol [mmol/l]

5.57 (4.97-6.05)

5.18 (4.37- 5.98)*

LDL [mmol/l]

3.46 ± 0.91

3.07 ± 1.04

HDL [mmol/l]

1.68 (1.31–1.98)

1.40 (1.15–1.61)*

Triglyceride [mmol/l]

1.16 (0.75–1.43)

1.67 (1.08–2.06)*

Regular medication [n (%)]

 ACE inhibitors

–

93 (61.5)

 ARBs

–

34 (22.5)

 CCBs

–

67 (44.4)

 Beta blockers

–

87 (57.6)

 Diuretics

–

68 (45)

 Antiplatelet drugs

–

44 (29.1)

 Statins

5 (15.7)

54 (35.7)

 Alprazolam

–

23 (15.2)

TEMPS-A

 Depressive

5.9 (4–7)

7.1 (5–9)

 Cyclothymic

2.9 (0–4)

3.9 (1–6)

 Hyperthymic

11.2 ± 4

11 (4.2)

 Irritable

3.2 (2–4)

4.3 (2–6)

 Anxious

4.1 (1–6)

6.3 (2–9)

BDI

2.8 (1–4)

6.3 (3–9)*

HAM-A

3.9 (1–6)

7.4 (2–10)*

Heart rate [1/min]

72.1 (66.6–78.2)

72.7 (64.1–77.2)

Brachial SBP [Hgmm]

125.5 ± 9.3

133.0 ± 12.3*

Brachial DBP [Hgmm]

72 ± 6.4

75 ± 9

Brachial PP [Hgmm]

51.5 (46.4–56.7)

56.7 (46.4–63)*

Central SBP [Hgmm]

117 (111.2–122.3)

124.1 (113.4–131.6)*

Central DBP [Hgmm]

67.1 ± 7

69.8 ± 8.2

Central PP [Hgmm]

49.9 (43.2–54.5)

54.3 (45.2–61)

PP amplification

1.08 (1.03–1.14)

1.07 (0.98–1.12)

PWV [m/sec]

8.6 (7.4–9.2)

9.3 (7.8–10)

AIx (%)

13.2 (5.75–23)

17.8 (8.5–25.1)

Serum BDNF (pg/ml)

21202.6 ± 6045.5

24880 ± 8279*