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Table 1 Demographic, laboratory, hemodynamic, and arterial stiffness parameters; subjects’ questionnaire scores

From: Hyperthymic affective temperament and hypertension are independent determinants of serum brain-derived neurotrophic factor level

  CONT HT
N (male:female) 32 (12:20) 151 (58:93)
Age [year] 61.1 (55.9–70.5) 63.7 (57–71)
Duration of hypertension [year] 11 (5–18)
Diabetes [n (%)] 38 (25.2)
Cardiovascular disease [n (%)] 21 (13.9)
Current smoker [n (%)] 3 (9.4) 22 (14.6)
Body height [cm] 168.8 ± 8.6 166.8 ± 8.6
Body weight [kg] 72.4 ± 12.1 79.7 ± 14*
BMI [kg/m2] 24.5 ± 5.4 28.6 ± 4.5*
Platelet count [G/l] 239.6 (215–277) 257 (209.7–303.2)
Glucose [mmol/l] 5.36 (4.88–5.81) 6.15 (5.11–6.7)*
GFR-EPI [ml/min/1.73 m2] 79.7 (69.5–82.2) 77.9 (67–90)
Uric acid [µmol/l] 313.7 ± 11.6 318.4 ± 6.3
Cholesterol [mmol/l] 5.57 (4.97-6.05) 5.18 (4.37- 5.98)*
LDL [mmol/l] 3.46 ± 0.91 3.07 ± 1.04
HDL [mmol/l] 1.68 (1.31–1.98) 1.40 (1.15–1.61)*
Triglyceride [mmol/l] 1.16 (0.75–1.43) 1.67 (1.08–2.06)*
Regular medication [n (%)]
 ACE inhibitors 93 (61.5)
 ARBs 34 (22.5)
 CCBs 67 (44.4)
 Beta blockers 87 (57.6)
 Diuretics 68 (45)
 Antiplatelet drugs 44 (29.1)
 Statins 5 (15.7) 54 (35.7)
 Alprazolam 23 (15.2)
TEMPS-A
 Depressive 5.9 (4–7) 7.1 (5–9)
 Cyclothymic 2.9 (0–4) 3.9 (1–6)
 Hyperthymic 11.2 ± 4 11 (4.2)
 Irritable 3.2 (2–4) 4.3 (2–6)
 Anxious 4.1 (1–6) 6.3 (2–9)
BDI 2.8 (1–4) 6.3 (3–9)*
HAM-A 3.9 (1–6) 7.4 (2–10)*
Heart rate [1/min] 72.1 (66.6–78.2) 72.7 (64.1–77.2)
Brachial SBP [Hgmm] 125.5 ± 9.3 133.0 ± 12.3*
Brachial DBP [Hgmm] 72 ± 6.4 75 ± 9
Brachial PP [Hgmm] 51.5 (46.4–56.7) 56.7 (46.4–63)*
Central SBP [Hgmm] 117 (111.2–122.3) 124.1 (113.4–131.6)*
Central DBP [Hgmm] 67.1 ± 7 69.8 ± 8.2
Central PP [Hgmm] 49.9 (43.2–54.5) 54.3 (45.2–61)
PP amplification 1.08 (1.03–1.14) 1.07 (0.98–1.12)
PWV [m/sec] 8.6 (7.4–9.2) 9.3 (7.8–10)
AIx (%) 13.2 (5.75–23) 17.8 (8.5–25.1)
Serum BDNF (pg/ml) 21202.6 ± 6045.5 24880 ± 8279*
  1. Continuous data are presented as mean (SD) or mean (interquartile range)
  2. Categorical parameters are presented as % (n)
  3. BMI body mass index, ARBs angiotensin II receptor blockers, CCBs calcium channel blockers, SBP systolic blood pressure, DBP diastolic blood pressure, PP pulse pressure, PWV pulse wave velocity, AIx augmentation index, TEMPS-A Temperament Evaluation of Memphis, Pisa, Paris and San Diego Autoquestionnaire, BDI Beck depression inventory, HAM-A Hamilton anxiety scale
  4. * p < 0.05