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Table 3 Averaged cortical thickness (mm) of the OFC in MDD patients and HCs

From: Regional cortical thinning of the orbitofrontal cortex in medication-naïve female patients with major depressive disorder is not associated with MAOA-uVNTR polymorphism

 

Cortical thickness

F

P

MDD patients

HCs

Left OFC

2.49 (0.14)

2.56 (0.16)

7.941

0.006*

Right OFC

2.50 (0.14)

2.63 (0.17)

17.447

<0.001*

Left medial OFC

2.43 (0.13)

2.53 (0.20)

8.117

0.006**

Left lateral OFC

2.53 (0.16)

2.58 (0.17)

3.971

0.050

Right medial OFC

2.38 (0.17)

2.57 (0.20)

21.795

<0.001**

Right lateral OFC

2.57 (0.14)

2.68 (0.19)

9.932

0.002**

  1. ANCOVA analysis with age as a covariate. All data are given as mean (standard deviation)
  2. OFC orbitofrontal cortex, MDD major depressive disorder, HCs healthy controls
  3. * Significance level was corrected for multiple comparisons using Bonferroni correction; p < 0.05/2 = 0.025
  4. ** Significance level was corrected for multiple comparisons using Bonferroni correction; p < 0.05/4 = 0.0125