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Table 1 Clinical and demographic characteristics of OCD patients and HCs

From: A pilot study exploring the association of morphological changes with 5-HTTLPR polymorphism in OCD patients

  OCD patients (n = 40) HCs (n = 40) P value
Age (years, mean ± SD)a 35.40 ± 12.07 39.70 ± 12.97 0.129
Gender (female/male)b 20/20 26/14 0.175
Handedness (right/left)b 37/3 39/1 0.305
Education (years, mean ± SD)a 13.69 ± 2.43 15.15 ± 1.35 0.001
Illness duration (years, mean ± SD) 11.33 ± 10.10   
Age of onset (years, mean ± SD) 23.98 ± 11.24   
Total Y-BOCS (total score, mean ± SD) 21.95 ± 6.32   
HDRS (17 items)a 6.08 ± 6.87 0.55 ± 0.88 0.000
5-HTTLPRa    
 14/14 26 17 0.040
 14/16 13 22  
 16/16 1 1  
LA allele carriers (SLA, LALG, LALA)b 10 20 0.021
Non-LA allele carriers (SS, SLG, LGLG)b 30 20  
  1. We found a significant difference between the OCD patients and HCs in the distribution of LA allele carriers or non-LA allele carriers of 5-HTTLPR polymorphism
  2. a T test
  3. bChi square test