Table 3 VBM analysis including association of variance between 5-HTTLPR polymorphisms and GM volumes in OCD patients and HCs
Regions | Brodmann area | Cluster size | Z | Talairach coordinates |
|---|---|---|---|---|
x, y, z (mm2) | ||||
Main effects | Â | Â | Â | Â |
 Diagnosis effects (P < 0.05, FWE, 〈k〉 = 77.666) |  |  |  |  |
 R hippocampus (OCD patients < HCs) |  | 763 | 5.08 | 33, −16, −18 |
 L precentral gyrus (OCD patients > HCs) | 4 | 797 | 4.88 | −28, −27, 64 |
Genotype effects | Â | Â | Â | Â |
 No suprathreshold clusters |  |  |  |  |
 Genotype-diagnosis interaction effects (P < 0.001, uncorrected, 〈k〉 = 63.146) |  |  |  |  |
R frontal pole | 10 | 112 | 4.35 | 26, 50, −6 |