Skip to main content

Table 1 Characteristics of all studies included in the meta-analysis NLGN4X SNP rs3747333 and rs3747334

From: Analysis of the SNP rs3747333 and rs3747334 in NLGN4X gene in autism spectrum disorder: a meta-analysis

Author, year Ethnicity Study design Presence in patients/sex ratio Presence in controls/sex ratio Genotyping type Diagnostic criteria Nucleotide change
Mikhailov (2014) Thai Screening 9/143 5.8 M:1F vs.dpSNP Unknown DHPLCa DSM-IVd c.1777 C>T
Volaki (2013) Greek Screening 11/40 9 M:1F vs.dpSNP Unknown PCR-DSb DSM-IV c.1777 C>T
Wermter (2008) German Screening 7/107 20.4 M:1F vs.dpSNP Unknown PCR–RFLPc ICD-10e c.1777 C>T
Blasi (2006) Italy Screening 4/31 3.5 M:1F vs.dpSNP Unknown PCR-RFLPc DSM-IV c.1777 C>T
Gauthier (2005) Quebec Case–control 61/96 6.4 M:1F 56/96 8.6 M:1F NA DSM-IV, ADI-Rf and ADOS-Gg c.1777 C>T
Xiaojuan (2014) Chinese Case–control 21/318 5.6 M:1F 4/453 3.0 M:1F PCR-DS DSM-IV and CARSh c.1777 C>T
  1. aDenaturing high-performance liquid chromatography (DHPLC)
  2. bPolymerase chain reaction-direct sequencing (PCR-DS)
  3. cPolymerase chain reaction-based restriction fragment length polymorphisms (PCR-RFLP)
  4. dDiagnostic and Statistical Manual of Mental Disorders, 4th ed. (DSM-IV)
  5. eTenth Revision of the International Classification of Diseases (ICD–10)
  6. fAutism specific parent interview (ADI-R)
  7. gAutism diagnostic observation scale (ADOS-G)
  8. hChildhood autism rating scale (CARS)