A comparison of sexual desire in opiate-dependent men receiving methadone and buprenorphine maintenance treatment

Table 2 Comparison of mean Mal-IIEF-15 domain scores, SDI-2-BM, total testosterone and prolactin in patients with sexual partners in the MMT and BMT groups

	MMT (n = 95)	BMT (n = 31)	Mean difference^a	p value^b
	mean ± SD	mean ± SD	Mean difference^a	p value^b
Mal-IIEF-15 domain
Erectile function	21.09 ± 7.91	23.33 ± 7.71	− 2.23	0.23
Orgasmic function^c	7.21 ± 4.97	7.15 ± 2.93	0.06	0.96
Sexual desire	6.14 ± 1.76	7.59 ± 1.54	− 1.46	0.001**
Intercourse satisfaction	8.59 ± 3.67	9.60 ± 3.54	− 1.01	0.25
Overall satisfaction	7.09 ± 2.31	7.93 ± 2.14	− 0.11	0.84
Total	48.87 ± 17.10	59.60 ± 15.97	− 4.75	0.23
DSD	27.74 ± 10.95	33.39 ± 11.18	− 5.66	0.04*
SSD	5.25 ± 5.00	4.15 ± 3.74	1.09	0.37
Total testosterone (nmol/L)	12.46 ± 7.64	18.45 ± 9.40	− 5.99	0.005**
Total testosterone (ng/dL)	359.37 ± 220.35	532.13 ± 271.11
Prolactin (μIU/mL)	162.12 ± 102.69	165.20 ± 67.71	− 2.77	0.91

BMT, buprenorphine maintenance treatment, MMT, methadone maintenance treatment; Mal-IIEF-15, Malay version of the International Index of Erectile Function 15; SDI-2-BM, Malay version of the Sexual Desire Inventory-2; DSD, dyadic sexual desire; SSD, solitary sexual desire; SD, standard deviation, nmol/L, nanomoles per liter; ng/dL, nanograms per decilitre; μIU/mL, macro international units per milliliter
* p < 0.05, ** p < 0.01
^aAdjusted mean difference with education Level, hepatitis C status, total Malay version of self-rated Montgomery-Asberg Depression Rating Scale (MADRS-BM) score, social functioning total score, health total score and Q score for tobacco as covariates
^bAdjusted for multiple comparisons using Bonferroni correction
^cA generalized linear model approach was used because the variables were not normally distributed

ISSN: 1744-859X