Table 1 The results of enrichment analysis for genes involved in the pathogenesis of both OCD and BD

1

Calcium voltage-gated channel subunit alpha1 C

CACNA1C

0.338153

2

Glutamate ionotropic receptor AMPA-type subunit 1 

GRIA1

0.1574122

3

Dopamine receptor D2

DRD2

0.1136524

4

Nitric oxide synthase 1

NOS1

0.0903783

5

Solute carrier family 18 member A1

SLC18A1

0.0661232

6

5-Hydroxytryptamine receptor 2A

HTR2A

0.0660831

7

Dopamine receptor D1

DRD1

0.0500920

8

Glutamate ionotropic receptor kainate-type subunit 2

GRIK2

0.0481045

9

Dopamine receptor D5

DRD5

0.0458659

10

5-Hydroxytryptamine receptor 1A, serotonin receptor

HTR1A

0.0443705

11

Glutamate ionotropic receptor NMDA-type subunit 2B

GRIN2B

0.036738

12

Solute carrier family 6 member 4

SLC6A4

0.020317

13

Glutamate ionotropic receptor kainate-type subunit 3

GRIK3

0.038491

14

Dopamine receptor D3

DRD3

0.017168

15

Cannabinoid receptor 1

CNR1

0.007217

16

Adrenoceptor alpha 1A

ADRA1A

0.006255

17

Brain-derived neurotrophic factor

BDNF

0.005617

18

Tryptophan hydroxylase 2

TPH2

0.0045508

19

Dopamine receptor D4

DRD4

0.004232

20

Glutamate decarboxylase 1

GAD1

0.003155

21

Gamma-aminobutyric acid type A receptor alpha1 subunit 

GABRA1

0.001786

22

Neurotrophic receptor tyrosine kinase 2

NTRK2

0.001023

23

Angiotensin I converting enzyme

ACE

0

24

Ataxin 1

ATXN1

0

25

Cholinergic receptor nicotinic alpha 7 subunit

CHRNA7

0

26

Corticotropin-releasing hormone receptor 2

CRHR2

0

27

Dopamine beta-hydroxylase

DBH

0

28

Ephrin A5

EFNA5

0

29

Glutamic acid decarboxylase 2

GAD2

0

30

Glutamate ionotropic receptor NMDA-type subunit 2A

GRIN2A

0

31

5-Hydroxytryptamine receptor 2C

HTR2C

0

32

5-Hydroxytryptamine receptor 3A

HTR3A

0

33

Olfactomedin 1

OLFM1

0

34

Tumor necrosis factor

TNF

0