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Table 4 Linear regression model of HRQoL on GASS categories and demographic characteristics

From: The impact on functioning of second-generation antipsychotic medication side effects for patients with schizophrenia: a worldwide, cross-sectional, web-based survey

Predictor: side effect GASS categories

Total Q-LES-Q-SF Score

(N = 435)

Multivariate estimate (SE)

Activating side effects

− 0.87 (0.86)

Sedating side effects

− 3.52 (0.94)*

Other side effects

− 1.73 (0.75)*

Age (continuous)

− 0.18 (0.06)*

Gender: female

− 1.68 (1.21)

Race/ethnicity: white

0.06 (1.80)

Education: at least some college

0.08 (1.21)

Employment status: employed (full or part time)

1.29 (1.16)

Living situation: live alone

− 0.40 (1.44)

Time since diagnosis (years, continuous)

0.31 (0.65)

  1. SE Standard Error, GASS Glasgow Antipsychotic Side-Effect Scale; HRQoL health-related quality of life, Q-LES-Q-SF Quality of Life Enjoyment and Satisfaction Questionnaire-Short Form. Activating side effects refer to restlessness, shaky hands or arms, and difficulty sleeping; sedating refers to sleepiness, feeling drugged or like a zombie and dizziness. Other refers to weight gain and problems enjoying sex. *p value significant at p < 0.05