Annals of General Psychiatry

Table 3 Associations between PHQ-9 scores, serum estradiol and testosterone by age and history of estrogen use

From: Associations between estradiol and testosterone and depressive symptom scores of the Patient Health Questionnaire-9 in ovariectomized women: a population-based analysis of NHANES data

Term		PHQ-9 score
Term		ß	95% CI	P value
Serum estradiol, pg/ml
Age^a	< = 60 (n = 166)	0.015	(− 0.054, 0.084)	0.663
Age^a	> 60 (n = 382)	0.007	(− 0.009, 0.022)	0.383
History of estrogen use^b	No (n = 18)	0.013	(− 0.004, 0.031)	0.136
History of estrogen use^b	Yes (n = 267)	0.014	(0.001, 0.027)	0.036
Serum testosterone, ng/dL
Age^a	< = 60 (n = 166)	− 0.057	(− 0.076, − 0.038)	< 0.001
Age^a	> 60 (n = 382)	− 0.004	(− 0.052, 0.045)	0.876
History of estrogen use^b	No (n = 18)	− 0.186	(− 0.331, − 0.040)	0.014
History of estrogen use^b	Yes (n = 267)	− 0.028	(− 0.042, − 0.014)	< 0.001

Significant values are shown in italic (p < 0.05)
^aAdjusted for education level, serum estradiol (pg/ml), serum testosterone (ng/dL), estrogen use duration (years), CVD chronic respiratory tract disease, arthritis
^bAdjusted for education level, serum estradiol (pg/ml), serum testosterone (ng/dL), CVD chronic respiratory tract disease, arthritis

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ISSN: 1744-859X

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