Table 2 Studies included for qualitative synthesis
Authors | Population | Intervention | Outcomes | Findings and results |
|---|---|---|---|---|
Fung et al. | 466 healthy men | Questionnaire about diet habit and correlation with other factors | FFQs | Major dietary patterns are predictors of plasma biomarkers of CVD and obesity risk |
Shah et al. | 1692 adult patients with inflammatory arthritis | Retrospective longitudinal cohort study evaluating the effect of depressive treatment on pain | SF-12v2, MCS, PCS | Depression treatment didn’t improve pain and health-related quality of life among adults with arthritis |
Apfelbacher et al. | Adult patients with inflammatory arthritis | Cross-sectional data from the 2002 World Health Survey | Self-reported depression | Positive association between inflammatory arthritis and depression in Western and Non-Western countries, suggesting that this relationship represents a universal phenomenon |
Matcham et al. | 56 RA patients | One-year prospective study | HADS | Symptoms of depression and anxiety have implications for disease activity |
Margaretten et al. | 172 RA patients | Evaluation of depression and health outcome | HAQ, PHQ-9, DAS-28 | Higher HAQ scores were associated with depression |
Katz et al. | 158 RA patients | Cross-sectional study on sources of fatigue in RA patients | Assessments of self-reported sleep quality, depression, physical activity, RA disease activity, muscle strength, functional limitations, body composition; information on demographics, medications, and smoking; the FSI | Fatigue in RA patients is a result of RA disease activity, pain, inactivity, depression, obesity and poor sleep |
Lu et al. | 8831 RA patients and 15,456 health controls | 14-year follow-up nationwide longitudinal study on bidirectional relationships between RA and depression | Demographic variables, urbanization level, baseline comorbidities, incidence of depression | A strong bidirectional relationships between RA and depression |
Figueiredo-Braga et al. | 82 RA patients, 73 SLE, 22 healthy subjects and 32 depressed control subjects | Cross-sectional study | FSS, HADS, PSQI, RAS, DAS28 | IL-10 and IL-6 are associated with depressive symptoms |
Hyphantis et al. | 524 patients affected by RA, SLE, SSc, Glaucoma and Colon cancer | Cross-sectional study to test the relative importance of depression in HRQOL in several chronic physical disorders | SCL-90 and WHO Quality of Life Instrument Short Form, HRQOL | SCL-90 somatization score significantly correlated to physical HRQOL in all diseases |