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Table 1 General characteristics of included studies

From: Malondialdehyde concentrations in obsessive–compulsive disorder: a systematic review and meta-analysis

Country (ethnicity) Control Case OCD diagnosis Method of MDA assay Sample size (Ca/Co) Age (Ca/Co) Gender (Ca/Co) Severity SYB Duration (years) Match Quality assessment Result Reference
Mean SD Mean SD F M Mild Mo Severe Vs
Iraq (Caucasian) 1.15 nmol/ml 1 1.67 3.28 NM ELISA (60/30) 18–68 years 43 47 NM NM NM NM NM NM NM 3 Mohamed et al. 2020
India (Asian) 3.85 unit/mg of protein 1.83 1.02 0.5 ICD-10-DCR Ohkawa (30/30) (23.86 ± 6.96/28.56) (19/19 (11/11) NM NM NM NM 23.8 ± 1.90 3.9 ± 2.9 Age and gender 6 Shrivtastava et al. 2017
Turkey (Caucasian) 10.32 nmol/ml 1.51 5.13 0.98 DSM IV Ohkawa (102/104) (38.75 ± 10.88/36.39 ± 10.35) (82/57 (20/47) NM NM NM NM NM 11.26 ± 8.56 Age and gender 5 Orhan et al. [34]
Bangladesh (Asian) 5.7 nmol/ml 1.7 4.3 1.2 DSM IV Satoh (48/48) (24.7 ± 4.6/21.3 ± 1) (6/6) (42/42) 16 18 14 NM NM  < 5 30,
5–10 8,
 > 10 10
Age, gender and socioeconomic status 7 Shohag et al. [22]
India (Asian) 4.89 nmol/ml 0.22 4.07 0.22 DSM IV Satoh (20/20) (29.70 ± 8.35/30.50 ± 9.34) (0/0) (20/20) NM NM NM NM NM Least of a year Age and gender 5 Behl et al. [32]
Turkey (Caucasian) 10.139 nmol/g Hb 8.68 6.032 6.57 DSM IV Jain (28/28) (28.28 ± 5.41/28.85 ± 5.54) (18/18 (10/10) 5 11 9 3 22.47 ± 5.39 NM Gender 6 Ozdemir et al. [26]
Turkey (Caucasian) 0.285 μmol/g Hb 0.05 0.198 0.03 DSM IV Jain (30/30) (29.2 ± 6.2/ 29.2 ± 7.2) (22/21) (8/9) NM NM NM NM NM NM Age and gender 6 Ersan et al. [23]
Turkey (Caucasian) 4.15 nmol/ml 0.73 2.5 0.41 DSM IV Satoh (34/32) (25.72 ± 7.04/29.13 ± 9.19) (22/19) (12/13) 4 9 18 3 NM 5.35 ± 3.12 Age and gender 6 Kuloglu et al. [33]
India (Asian) 12.63 nmol/ml RBC 2.91 8.84 0.46 DSM IV Wills (15/15) NM NM NM NM NM NM NM NM NM Age and gender 3 Kurup et al. [27]
  1. Ca case, Co control, SYB score of Y-BOCS, Mo moderate, Vs very severe, F female, M male, NM not mentioned by the authors/in the article