Evaluation of factors associated with medication adherence in patients with bipolar disorder using a medication event monitoring system: a 6‐month follow‐up prospective study

Table 4 Pearson correlation coefficients for MEMS-measured adherence and other variables

	MEMS-measured adherence (first measurement)	p-value
Age (years)	0.257	NS
Education (years)	−0.042	NS
Baseline weight (kg)	−0.108	NS
Weight change (kg)	0.176	NS
Baseline BMI	−0.059	NS
BMI change	0.170	NS
Duration of illness (months)	0.109	NS
Number of recurrent episodes	0.177	NS
Number of hospital admissions	0.041	NS
Number of medication tablets per day	0.024	NS
Prescription duration (days)	−0.321	0.023^*
CGI-S score	−0.127	NS
BPRS scores
Affect	−0.349	0.013^*
Positive symptoms	−0.068	NS
Negative symptoms	0.045	NS
Resistance	−0.256	NS
Activation	−0.240	NS
Total score	−0.244	NS
YMRS score	−0.070	NS
HAM-D score	−0.119	NS
MSPSS score	−0.029	NS
DAI score	−0.179	NS
MDIS score	−0.079	NS
UKU-SERS scores
Sleepiness, sedation	−0.089	NS
Weight gain	−0.098	NS

MEMS medication event monitoring system, NS not significant, BMI body mass index, CGI-S Clinical Global Impressions-Severity, BPRS Brief Psychiatric Rating Scale, YMRS Young Mania Rating Scale, HAM-D Hamilton Depression Rating Scale, MSPSS Multidimensional Scale of Perceived Social Support, DAI Drug Attitude Inventory, MDIS Mood Disorders Insight Scale, UKU-SERS Udvalg for Kliniske Undersøgelser Side Effect Rating Scale
^*p < 0.05; ^**p < 0.01

ISSN: 1744-859X