Evaluation of factors associated with medication adherence in patients with bipolar disorder using a medication event monitoring system: a 6‐month follow‐up prospective study

Table 5 Pearson correlation coefficients for 6-month changes in MEMS-measured adherence and other variables

	6-month changes in MEMS-measured adherence	p-value
Age (years)	−0.078	NS
Education (years)	−0.009	NS
Baseline weight (kg)	0.094	NS
Weight change (kg)	0.008	NS
Baseline BMI	0.005	NS
BMI change	−0.014	NS
Duration of illness (months)	−0.144	NS
Number of recurrent episodes	−0.261	NS
Number of hospital admissions	0.081	NS
Number of medication tablets per day	−0.082	NS
Prescription duration (days)	0.236	NS
CGI-S score	0.333	NS
BPRS scores
Affect	0.316	NS
Positive symptoms	−0.033	NS
Negative symptoms	−0.025	NS
Resistance	0.122	NS
Activation	0.161	NS
Total score	0.144	NS
YMRS score	0.154	NS
HAM-D score	0.283	NS
MSPSS score	−0.134	NS
DAI score	0.392	0.024^*
MDIS score	0.124	NS
UKU-SERS scores
Sleepiness, sedation	−0.112	NS
Weight gain	−0.537	0.005^**

MEMS medication event monitoring system, NS not significant, BMI body mass index, CGI-S Clinical Global Impressions-Severity, BPRS Brief Psychiatric Rating Scale, YMRS Young Mania Rating Scale, HAM-D Hamilton Depression Rating Scale, MSPSS Multidimensional Scale of Perceived Social Support, DAI Drug Attitude Inventory, MDIS Mood Disorders Insight Scale, UKU-SERS Udvalg for Kliniske Undersøgelser Side Effect Rating Scale
^*p < 0.05; ^**p < 0.01

ISSN: 1744-859X