Table 2 Dose of drugs for mood stabilizers, antipsychotics, antidepressants and BZRAs divided by age and sex
Sex | Age (years) | ||||||
|---|---|---|---|---|---|---|---|
Males | Females | Significance | ≤ 39 | 40–64 | ≥ 65 | Significance | |
N = 1408 | N = 1698 | N = 676 | N = 1899 | N = 531 | |||
Mood stabilizers | |||||||
Lithium | 599.9 (248.1) | 519.2 (235.4) | < 0.001 | 601.7 (275.7) | 579.7 (241.0) | 447.5 (186.0) | < 0.001 |
Valproate | 535.8 (272.0) | 504.2 (268.9) | 0.083 | 490.6 (281.6) | 543.7 (273.4) | 451.9 (231.6) | < 0.001 |
Lamotrigine | 160.2 (98.6) | 158.2 (103.0) | 0.780 | 159.9 (98.4) | 161.1 (103.6) | 143.0 (88.5) | 0.376 |
Carbamazepine | 354.9 (208.8) | 372.1 (197.4) | 0.606 | 352.3 (199.0) | 384.4 (211.7) | 288.0 (145.9) | 0.098 |
Other medications | |||||||
Antipsychotics | 206.0 (227.4) | 218.8 (264.1) | 0.302 | 196.2 (209.5) | 225.9 (268.5) | 180.3 (201.4) | 0.018 |
Antidepressants | 125.2 (101.1) | 127.1 (106.3) | 0.746 | 121.9 (97.6) | 131.5 (104.7) | 109.4 (108.1) | 0.024 |
BZRAs | 14.4 (19.5) | 15.1 (28.1) | 0.484 | 14.3 (27.4) | 15.6 (25.0) | 12.4 (19.9) | 0.078 |