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Table 1 Demographic and clinical characteristics

From: The economic and humanistic burden of bipolar disorder in adults in the United States

Characteristic

Respondents with bipolar disorder by depressive symptom severity

Respondents with bipolar disorder (n = 3285)

General population (n = 6570)

None/mild (n = 1401)

Moderate (n = 889)

Severe (n = 1293)

Age, mean (SD)

38.8 (14.5)

33.0 (12.2)a

34.4 (11.5)a

36.3 (13.3)

35.9 (14.7)

Female, n (%)

833 (59.5%)

513 (57.7%)a

848 (65.6%)a

2031 (61.8%)

4046 (61.6%)

Race/ethnicity, n (%)

 White

796 (56.8%)

439 (49.4%)a

738 (57.1%)a

1828 (55.6%)

3585 (54.6%)

 Black

203 (14.5%)

132 (14.8%)a

134 (10.4%)a

433 (13.2%)

878 (13.4%)

 Hispanic

273 (19.5%)

208 (23.4%)a

310 (24.0%)a

700 (21.3%)

1443 (22.0%)

 Other

129 (9.2%)

110 (12.4%)a

111 (8.6%)a

324 (9.9%)

664 (10.1%)

Region, n (%)

 Northeast

241 (17.2%)

164 (18.4%)

203 (15.7%)

556 (16.9%)

1171 (17.8%)

 Midwest

283 (20.2%)

169 (19.0%)

234 (18.1%)

629 (19.1%)

1341 (20.4%)

 South

577 (41.2%)

393 (44.2%)

564 (43.6%)

1390 (42.3%)

2629 (40.0%)

 West

300 (21.4%)

163 (18.3%)

292 (22.6%)

710 (21.6%)

1429 (21.8%)

Marital status, n (%)

 Single

808 (57.7%)

521 (58.6%)

730 (56.5%)

1872 (57.0%)

3809 (58.0%)

 Married/living with Partner

593 (42.3%)

368 (41.4%)

563 (43.5%)

1413 (43.0%)

2761 (42.0%)

Education, n (%)

 Less than college/university

1012 (72.2%)

643 (72.3%)a

988 (76.4%)a

2405 (73.2%)

4832 (73.5%)

 College/university degree or higher

389 (27.8%)

246 (27.7%)a

305 (23.6%)a

880 (26.8%)

1738 (26.5%)

Any employment (full-time/part-time/self-employed), n (%)

721 (51.5%)

517 (58.2%)a

647 (50.0%)a

1743 (53.1%)

3506 (53.4%)

Any health insurance, n (%)

1164 (83.1%)

719 (80.9%)a

1008 (78.0%)a

2672 (81.3%)

5308 (80.8%)

Annual household income, n (%)

 Less than $50,000

880 (62.8%)

521 (58.6%)a

854 (66.0%)a

2055 (62.6%)

4227 (64.3%)

 $50,000 or greater

521 (37.2%)

368 (41.4%)a

439 (34.0%)a

1230 (37.4%)

2343 (35.7%)

Smoking status, n (%)

 Never smoked

559 (39.9%)

383 (43.1%)a

411 (31.8%)a

1274 (38.8%)

2507 (38.2%)

 Former smoker

332 (23.7%)

178 (20.0%)a

262 (20.3%)a

736 (22.4%)

1518 (23.1%)

 Current smoker

510 (36.4%)

328 (36.9%)a

620 (48.0%)a

1275 (38.8%)

2545 (38.7%)

Any alcohol use, n (%)

884 (63.1%)

649 (73.0%)a

887 (68.6%)a

2197 (66.9%)

4388 (66.8%)

Any exercise in the past month, n (%)

909 (64.9%)

607 (68.3%)a

764 (59.1%)a

2103 (64.0%)

4240 (64.5%)

BMI, kg/m2, mean (SD)

29.4 (8.0)

28.7 (8.4)

28.9 (8.5)

28.9 (8.3)

28.9 (8.2)

CCI, mean (SD)

0.7 (2.0)

0.8 (1.6) a

1.1 (2.3) a

0.7 (1.4)

0.6 (1.4)b

Cardiometabolic comorbidities, n (%)

 Obesity

566 (39.7%)

303 (34.1%)a

486 (37.6%)a

1273 (38.8%)

2400 (36.5%)b

 Hypertension

309 (22.1%)

160 (18.0%)a

308 (23.8%)a

721 (21.9%)

1141 (17.4%)b

 Migraine

270 (19.3%)

207 (23.3%)a

417 (32.3%)a

827 (25.2%)

940 (14.3%)b

 Diabetes

176 (12.6%)

104 (11.7%)

147 (11.4%)

374 (11.4%)

623 (9.5%)

 Cardiovascular disease

123 (8.8%)

81 (9.1%)

145 (11.2%)

288 (8.8%)

431 (6.6%)b

 Cerebrovascular disease

47 (3.4%)

32 (3.6%)

63 (4.9%)

111 (3.4%)

149 (2.3%)b

PHQ-9, mean (SD)

4.9 (3.3)

12.1 (1.4)a

19.9 (3.9)a

12.0 (7.2)

7.6 (7.0)b

GAD-7, mean (SD)

5.7 (4.8)

10.1 (4.1)a

14.5 (4.9)a

9.9 (6.1)

6.1 (5.8)b

  1. BMI, body mass index; CCI, Charlson Comorbidity Index; GAD-7, 7-item General Anxiety Disorder scale; n, number of respondents; PHQ-9, Patient Health Questionnaire; SD, standard deviation
  2. aSignificant at p < 0.05 across depressive symptom severity cohorts [reference = none/mild]
  3. bSignificant at p < 0.05 for bipolar disorder vs. general population [reference]