Variable | Functional impairment status | COR (95%CI) | p-value | AOR (95%CI) | p-value | |
---|---|---|---|---|---|---|
 | No | Yes |  |  |  |  |
Marital status | Â | Â | Â | Â | Â | Â |
 Single | 81 | 84 | 1 |  < 0.001* | 1 |  |
 Married | 145 | 46 | 0.338(0.217–0.0525) | 0.052 | 0.383(0.171–0.857) | 0.020* |
 Widowed | 2 | 9 | 3.667(0.988–13.605) | 0.682 | 5.045(1.002–25.412) | 0.05 |
 Divorced | 17 | 23 | 1.150(0.589–2.247) |  | 1.231(0.491–3.085) | 0.657 |
Occupation | Â | Â | Â | Â | Â | Â |
 Civil servant | 42 | 18 | 1 |  | 1 |  |
 Private worker | 18 | 6 | 0.679(0.235–1.960) | 0.474 | 0.887(0.235–3.347) | 0.86 |
 Farmer | 41 | 22 | 1.325(0.633–2.772) | 0.455 | 1.201(0.443–3.256) | 0.72 |
 Housewife | 71 | 33 | 0.979(0.495–1.933) | 0.95 | 1.033(0.399–2.676) | 0.947 |
 Unemployed | 32 | 55 | 4.451(2.219–8.929) |  < 0.001** | 3.911(1.457–10.499) | 0.007* |
 Student | 46 | 27 | 1.427(0.700–2.909) | 0.328 | 0.762(0.259–2.245) | 0.622 |
Study area | Â | Â | Â | Â | Â | Â |
 Gondar | 118 | 62 | 1 | 0.709 | 1 | 0.98 |
 Felegehiwot | 104 | 61 | 1.086(0.703–1.680) |  < 0.001** | 2.823(1.493–5.334) | 0.002* |
 Tibebegion | 25 | 41 | 2.986(1.691–5.274) |  | 3.382(1.592–7.184) |  |
BMI | Â | Â | Â | Â | Â | Â |
 Normal | 190 | 124 | 1 | 0.695 | 1 | 0.322 |
 Underweight | 29 | 20 | 1.126(0.622–2.041) | 0.386 | 1.488(0.678–3.266) | 0.609 |
 Overweight | 26 | 14 | 0.742(0.377–1.1458) | 0.040* | 0.776(0.294–2.049) | 0.028* |
 Obese | 3 | 5 | 4.096(1.066–15.735) |  | 6.491(1.219–34.575) |  |
Type of BD | Â | Â | Â | Â | Â | Â |
 BD-I | 195 | 117 | 1 |  | 1 | 0.994 |
 BD-I with psychotic feature | 42 | 38 | 1.405(0.864–2.286) | 0.171 | 0.997(0.484–2.054) | 0.078 |
 BD-II | 9 | 10 | 2.646(1.111–6.302) | 0.028* | 3.303(0.874–12.481) |  |
Current mood status | Â | Â | Â | Â | Â | Â |
 Euthymic phase | 170 | 46 | 1 |  | 1 |  |
 Manic phase | 63 | 90 | 5.644(3.579–8.900) |  < 0.001** | 5.153(2.839–9.352) |  < 0.001** |
 Depressive phase | 15 | 27 | 6.453(3.265–12.752) |  < 0.001** | 7.794(3.313–18.338) |  < 0.001** |
Treatment duration | Â | Â | Â | Â | Â | Â |
 ≤ 1 year | 51 | 53 | 1 |  | 1 | 0.051 |
 1–5 year | 130 | 63 | 0.482(0.298–0.779) | 0.003* | 0.500(0.249–1.004) | 0.067 |
 5–10 year | 52 | 32 | 0.596(0.337–1.054) | 0.075 | 0.361(0.361–1.863) | 0.384 |
 > 10 year | 16 | 14 | 0.903(0.406–2.009) | 0.803 | 0.588(0.178–1.942) |  |
No of relapse per year | Â | Â | Â | Â | Â | Â |
 No relapse | 164 | 70 | 1 |  < 0.001** | 1 | 0.006* |
 Once relapse | 75 | 78 | 2.494(1.640–3.792) |  < 0.001** | 2.235(1.254–3.984) |  < 0.001** |
 ≥ two relapses | 9 | 15 | 5.067(2.186–11.744) |  | 8.303(2.725–25.295) |  |
Suicidal ideation | Â | Â | Â | Â | Â | Â |
 Yes | 25 | 49 | 1 |  < 0.001** | 1 | 0.008* |
 No | 227 | 110 | 0.260(0.156–0.436) |  | 0.415(0.216–0.795) |  |
Suicidal attempt | Â | Â | Â | Â | Â | Â |
 Yes | 6 | 19 | 1 |  < 0.001** | 1 | 0.99 |
 No | 240 | 146 | 0.206(0.090–0.473) |  | 1.009(0.271–3.751) |  |
Lifetime substance use | Â | Â | Â | Â | Â | Â |
 Yes | 119 | 91 | 1 | 0.084 | 1 | 0.226 |
 No | 131 | 70 | 0.709(0.479–1.048) |  | 0.669(0.349–1.283) |  |
3-month substance use | Â | Â | Â | Â | Â | Â |
 Yes | 20 | 31 | 1 | 0.001** | 1 | 0.028* |
 No | 228 | 132 | 0.363(0.204–0.645) |  | 0.413(0.188–0.908) |  |
No of hospitalization | Â | Â | Â | Â | Â | Â |
 | 120 | 63 | 1 | 0.061 | 1 | 1 |
 No | 86 | 67 | 1.521(0.981–2.358) | 0.071 | 1.513(0.810–2.825) | 0.194 |
 Once | 32 | 25 | 1.722(0.954–3.110) | 0.152 | 1.502(0.604–3.735) | 0.381 |
 Twice | 9 | 8 | 1.968(0.779–4.976) |  | 0.951(0.237–3.816) | 0.944 |
 ≥ three |  |  |  |  |  |  |
Adherence | Â | Â | Â | Â | Â | Â |
 Adherent | 31 | 60 | 1 |  | 1 |  |
 Non-adherent | 218 | 102 | 4.496(2.763–7.317) |  < 0.001** | 3.212(1.706–6.048) |  < 0.001** |
Medication acquisition | Â | Â | Â | Â | Â | Â |
 Health insurance | 104 | 97 | 1 | 0.001** | 1 | 0.007* |
 Out of pocket | 139 | 71 | 0.515(0.347–0.764) |  | 0.457(0.259–0.807) |  |
Medication discontinuation | Â | Â | Â | Â | Â | Â |
 Yes | 102 | 82 | 1 | 0.016* | 1 | 1 |
 No | 146 | 81 | 0.618(0.417–0.915) |  | 0.695(0.373–1.294 | 0.251 |
Current regimen types | Â | Â | Â | Â | Â | Â |
 MS plus AP | 160 | 120 | 1 |  | 1 | 1 |
 MS plus AD | 6 | 6 | 1.301(0.410–4.132) | 0.656 | 0.877(0.147–5.222) | 0.885 |
 MS alone | 20 | 5 | 0.434(0.179–1.053) | 0.065 | 6.324(0.270–148.401 | 0.252 |
 AP alone | 45 | 18 | 0.488(0.270–0.880) | 0.017 | 5.643(0.258–123.642 | 0.272 |
 AP plus MD | 6 | 3 | 0.557(0.141–2.200) | 0.404 | 0.924(0.162–5.285) | 0.929 |
 MS plus AP plus AD | 12 | 10 | 1.301(0.565–2.995) | 0.537 | 1.484(0.418–188.275 | 0.542 |