Clinical and pharmacological studies of obsessive-compulsive disorder (OCD) have suggested that the serotonergic systems are involved in the pathogenesis, while structural imaging studies have found some neuro...
Despite marked costs and limited evidence regarding effectiveness, occupational therapy (OT) is widely applied in psychiatric settings and financed by health insurance companies in European countries. This pil...
Authors: Marc-Andreas Edel, Brian Blackwell, Markus Schaub, Barbara Emons, Tanja Fox, Friederike Tornau, Bernward Vieten, Patrik Roser, Ida Sibylle Haussleiter and Georg Juckel
There have been many studies on psychiatric disorders, but very little is known about the biology of suicide with schizophrenia. In the present study, we are looking for a possible connection between altered l...
Authors: Rym Mensi, Amal Messaoud, Ahmed Mhallah, Islem Azizi, Walid Haj Salah, Wahiba Douki, Mohamed Fadhel Najjar and Lotfi Gaha
The present study aimed to investigate the mental health status in patients with asthma and assess the effects of asthma on suicidal ideation and attempts using a representative sample from Korea.
Authors: Jae Ho Chung, Sun- Hyun Kim and Yong Won Lee
Charge-free heroin use disorder treatment in Italy follows two main approaches, i.e., harm reduction treatment (HRT) strategy in community low-threshold facilities for drug addiction and opioid agonist treatme...
Authors: Jacopo V. Bizzarri, Valentina Casetti, Livia Sanna, Angelo Giovanni Icro Maremmani, Luca Rovai, Silvia Bacciardi, Daria Piacentino, Andreas Conca and Icro Maremmani
Parental bonding has been implicated in smoking behavior, and the quality of maternal bonding (MB) has been associated with poor mental health and substance use. However, little is known about the association ...
Authors: Iren Csala, Monika Elemery, Fruzsina Martinovszky, Peter Dome, Balazs Dome, Gabor Faludi, Imola Sandor, Zsuzsa Gyorffy, Emma Birkas and Judit Lazary
The Dissociative Experience Scale for adolescent (A-DES), a 30-item, multidimensional, self-administered questionnaire, was validated using a large sample of American young people sample. We reported the lingu...
Authors: Concetta De Pasquale, Federica Sciacca and Zira Hichy
Previous literature has found fluoxetine to be relatively safe in overdose. This study hopes to examine this idea along with support from published pharmacokinetic information including serum fluoxetine and no...
A specific psychopathology of addiction has been proposed and described using the self-report symptom inventory (SCL-90), leading to a 5-factor aggregation of psychological/psychiatric symptoms: ‘worthlessness...
Authors: Angelo G. I. Maremmani, Pier Paolo Pani, Emanuela Trogu, Federica Vigna-Taglianti, Federica Mathis, Roberto Diecidue, Ursula Kirchmayer, Laura Amato, Joli Ghibaudi, Antonella Camposeragna, Alessio Saponaro, Marina Davoli, Fabrizio Faggiano and Icro Maremmani
Previous studies have shown that personality characteristics affect sexual functioning. The aim of this exploratory study was to assess and describe the relationship between global personality traits and the s...
Authors: Jacek Kurpisz, Monika Mak, Michał Lew-Starowicz, Krzysztof Nowosielski, Przemysław Bieńkowski, Robert Kowalczyk, Błażej Misiak, Dorota Frydecka and Jerzy Samochowiec
This study aimed to evaluate whether selecting mirtazapine as the first choice for current depressive episode instead of selective serotonin reuptake inhibitors (SSRIs) reduces benzodiazepine use in patients w...
Orbitofrontal cortex alterations have been suggested to underlie the impaired mood regulation in depression. MAOA-uVNTR (monoamine oxidase A-upstream variable number of tandem repeats) polymorphism has been repor...
Authors: Eunsoo Won, Sunyoung Choi, June Kang, Min-Soo Lee and Byung-Joo Ham
Quality of life can be perceived as a subjective assessment of different aspects of human functioning. Personality is a factor which determines actions taken by individuals and their tendency to perceive reali...
Authors: Daria Schneider-Matyka, Anna Jurczak, Agnieszka Samochowiec, Beata Karakiewicz, Małgorzata Szkup, Anna Grzywacz and Elżbieta Grochans
Alterations in one-carbon metabolism (OCM) have been observed in patients with schizophrenia (SZ), but a comprehensive study of OCM has not yet been conducted. A carbon atom is transferred from l-serine to methio...
The objective of this study was to describe the profile and alcoholic status of a population with alcohol use disorders (AUD) requesting help from a psychiatric hospital to stop drinking, as well as their clin...
Authors: Philippe Nubukpo, Murielle Girard, Jean-Marie Sengelen, Sophie Bonnefond, Aurélien Varnoux, Benoît Marin and Dominique Malauzat
Longer treatment duration is important for the successful treatment of gambling disorder (GD). This retrospective study investigated the factors and interventions that might enhance treatment duration in GD p...
Authors: Sam-Wook Choi, Young-Chul Shin, HyunChul Youn, Se-Won Lim and Juwon Ha
It is well known that suicidal rates vary considerably among European countries and the reasons for this are unknown, although several theories have been proposed. The effect of economic variables has been ext...
Authors: Konstantinos N. Fountoulakis, Isaia Chatzikosta, Konstantinos Pastiadis, Prodromos Zanis, Wolfram Kawohl, Ad J. F. M. Kerkhof, Alvydas Navickas, Cyril Höschl, Dusica Lecic-Tosevski, Eliot Sorel, Elmars Rancans, Eva Palova, Georg Juckel, Goran Isacsson, Helena Korosec Jagodic, Ileana Botezat-Antonescu…
Major depressive disorder (MDD) is a common psychiatric disorder with considerable mortality. Death from unnatural causes, largely suicidal or quasi-suicidal, has a particularly high risk for the functional di...
Authors: Mohamed Amine Sayadi, Ons Achour, Asma Ezzaher, Ilham Hellara, Asma Omezzine, Wahiba Douki, Ali Bousslama, Lotfi Gaha and Mohamed Fadhel Najjar
Brain-derived neurotrophic factor (BDNF) has neuroprotective, proangiogenic and myogenic effects and, therefore, possibly acts as a psychosomatic mediator. Here, we measured serum BDNF (seBDNF) level in hypert...
Authors: János Nemcsik, Andrea László, Lilla Lénárt, Dániel Eörsi, Péter Torzsa, Beáta Kőrösi, Orsolya Cseprekál, András Tislér, Ádám Tabák, Xenia Gonda, Zoltán Rihmer, Judit Hodrea, Zsófia Nemcsik-Bencze and Andrea Fekete
Investing in financial markets is promoted and protected by the government as an essential economic activity, but can turn into a gambling addiction problem. Until now, few scales have widely been used to iden...
Authors: HyunChul Youn, Jung-Seok Choi, Dai-Jin Kim and Sam-Wook Choi
Conflicting evidence exists about the relationship between psychotic symptoms and suicidality in mood disorders. We aimed to investigate the lifetime suicidality and its relationship with dimensions of the psy...
Authors: Camilla Gesi, Claudia Carmassi, Mario Miniati, Antonella Benvenuti, Gabriele Massimetti and Liliana Dell’Osso
The relationship between mental stress and cardiovascular disease has been shown in several studies. Panic disorder (PD) is also associated with cardiovascular disease due to increased risk of myocardial infar...
Authors: Omer Yanartas, Murat Sunbul, Zeynep Senkal, Erdal Durmus, Tarik Kivrak, Nilufer Subasi, Gulhan Karaer, Serhat Ergun, Ibrahim Sari and Kemal Sayar
We previously found a five cluster of psychological symptoms in heroin use disorder (HUD) patients: ‘worthlessness-being trapped’, ‘somatic-symptoms’, ‘sensitivity-psychoticism’, ‘panic-anxiety’, and ‘violence...
Authors: Pier Paolo Pani, Angelo G. I. Maremmani, Emanuela Trogu, Federica Vigna-Taglianti, Federica Mathis, Roberto Diecidue, Ursula Kirchmayer, Laura Amato, Joli Ghibaudi, Antonella Camposeragna, Alessio Saponaro, Marina Davoli, Fabrizio Faggiano and Icro Maremmani
Approximately one-third of stroke survivors suffer from post-stroke depression (PSD) in the acute or chronic stages. The presence of PSD in the acute stage after stroke is reportedly associated with poor patie...
Authors: Norifumi Metoki, Norio Sugawara, Joji Hagii, Shin Saito, Hiroshi Shiroto, Tetsu Tomita, Minoru Yasujima, Ken Okumura and Norio Yasui-Furukori
Beck’s cognitive theory postulates that dysfunctional attitudes predisposing to depression are formed by early negative experiences. Meanwhile, Bowlby’s attachment theory contends that distorted working models...
Authors: Koichi Otani, Akihito Suzuki, Yoshihiko Matsumoto and Masanori Enokido
The character higher order scales (self-directedness, cooperativeness, and self-transcendence) in the temperament and character inventory are important general measures of health and well-being [Mens Sana Mono...
Authors: Nigel Lester, Danilo Garcia, Sebastian Lundström, Sven Brändström, Maria Råstam, Nóra Kerekes, Thomas Nilsson, C. Robert Cloninger and Henrik Anckarsäter
Bipolar I and II represent the most common and severe subtypes of bipolar disorder. Although bipolar I disorder is relatively well studied, the clinical characteristics and response to treatment of patients wi...
Authors: Catherine Datto, William J. Pottorf, Louisa Feeley, Scott LaPorte and Charlie Liss
The Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) recently included sensory processing abnormalities in the diagnostic criteria for individuals with autism spectrum disorder (ASD)...
Authors: Yuka Yasuda, Ryota Hashimoto, Aya Nakae, Hongling Kang, Kazutaka Ohi, Hidenaga Yamamori, Michiko Fujimoto, Satoshi Hagihira and Masatoshi Takeda
The arduous emotional and physical nurses’ work, the gradual nursing staff cutbacks and the lack of recognition that nurses feel regarding their skills and overall capabilities are some of the factors that act...
Authors: Christina Karatza, Sofia Zyga, Styliani Tziaferi and Panagiotis Prezerakos
Lamotrigine is an effective anticonvulsant drug that has also been demonstrated to be effective in the treatment of bipolar disorder. We report a case of rhabdomyolysis after intentional overdose in a woman ag...
Authors: Sokratis E. Karaoulanis, Markos Syngelakis and Konstantinos Fokas
One of the major factors affecting treatment compliance and outcome in patients is the wide range of side effects (SEs) associated with antidepressants. In the present study, we aimed to assess the extent to w...
Authors: Uri Nitzan, Tal Bekerman, Gideon Becker, Pesach Lichtenberg, Shaul Lev-Ran, Garry Walter, Hagai Maoz and Yuval Bloch
It is often difficult to differentiate between the depressive states seen in late-life depression and late-onset Alzheimer’ disease (AD) in the clinical setting.
Authors: Yoshiaki Tsuruoka, Michio Takahashi, Masatoshi Suzuki, Koichi Sato and Yukihiko Shirayama
We investigated the serum levels of brain-derived neurotrophic factor (BDNF), proBDNF and plasma 3-methoxy-4-hydroxyphenylglycol (MHPG) levels in patients with chronic schizophrenia.
Authors: Reiji Yoshimura, Hikaru Hori, Asuka Katsuki, Kiyokazu Atake and Jun Nakamura
To determine the timing of development of suicidal ideation and factors associated therewith in suicide attempters who required psychiatric emergency treatment.
Authors: Kotaro Otsuka, Hikaru Nakamura, Kaoru Kudo, Jin Endo, Katsumi Sanjo, Kentaro Fukumoto, Katsuhito Hoshi, Junko Yagi and Akio Sakai
It still remains unclear whether non-suicidal self-injury (NSSI) in young adult populations represents an actual symptom leading to psychiatric illness, constitutes a disorder itself or is rather a cultural pe...
Authors: Rachel Stroehmer, Marc A. Edel, Steffi Pott, Georg Juckel and Ida S. Haussleiter
The relationship between violence and neurocognitive function in schizophrenia is unclear. We examined the backgrounds and neurocognitive functions of violent and nonviolent patients with schizophrenia to iden...
We have shown that serotonin transporter (SERT) clustering in blood lymphocytes is altered in major depression and correlates with pharmacological therapeutic responses measured with the Hamilton scale. In the...
Authors: Tania Rivera-Baltanas, Roberto Carlos Agis-Balboa, Raquel Romay-Tallon, Lisa E. Kalynchuk, Jose Manuel Olivares and Hector J. Caruncho
A high prevalence of cannabis use disorder has been reported in subjects suffering from schizophrenia, fuelling intense debate about whether schizophrenia with pre-onset cannabis use disorder may be a distinc...
Authors: Samuel Sarrazin, Florence Louppe, Raphael Doukhan and Franck Schürhoff
The aim of the aricle is to study the relationship between attachment, parental rearing behavior, and (infant and current) ADHD symptoms with emotion processing and alexithymia in adults with ADHD.
Authors: Marc-Andreas Edel, Susanne Edel, Marie Krüger, Hans-Jörg Assion, Georg Juckel and Martin Brüne
During the last decades, there have been many different opinions concerning the neurocognitive function in Bipolar disorder (BD). The aim of the current study was to perform a systematic review of the literatu...
Authors: Eirini Tsitsipa and Konstantinos N. Fountoulakis
Bipolar disorder is a chronic mood disorder with episodic progress and high relapse rate. Growing evidence suggests that individuals with bipolar disorder display cognitive impairment which persists even throu...
Authors: Mădălina Vrabie, Victor Marinescu, Anca Talaşman, Oana Tăutu, Eduard Drima and Ioana Micluţia
Schizophrenia is a chronic mental disorder that leads to disability in several aspects of the individual’s personal, social, and occupational functioning. This study assesses and compares the level of disabili...
Authors: Adesanmi Akinsulore, Boladale M. Mapayi, Olutayo O. Aloba, Ibidunni Oloniniyi, Femi O. Fatoye and Roger O. A. Makanjuola
Clozapine is widely prescribed and, although effective, can cause weight gain and dysglycemia. The dysmetabolic effects of clozapine are thought to be more prevalent in women with this gender on average attain...
Authors: Simon G. Anderson, Mark Livingston, Lewis Couchman, Daniel J. Smith, Moira Connolly, Joan Miller, Robert J. Flanagan and A. H. Heald
To the best of our knowledge, there are no case studies of serotonin syndrome (SS) in patients with autism spectrum disorder. We report the case of a 33-year-old male who presented SS under the combined use of...
Authors: Kalliopi N. Nikolaou, Rossetos Gournellis, Ioannis Michopoulos, Georgios Dervenoulas, Christos Christodoulou and Athanasios Douzenis
