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  1. Content type: Primary research

    We investigated the serum levels of brain-derived neurotrophic factor (BDNF), proBDNF and plasma 3-methoxy-4-hydroxyphenylglycol (MHPG) levels in patients with chronic schizophrenia.

    Authors: Reiji Yoshimura, Hikaru Hori, Asuka Katsuki, Kiyokazu Atake and Jun Nakamura

    Citation: Annals of General Psychiatry 2016 15:1

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  2. Content type: Primary Research

    To determine the timing of development of suicidal ideation and factors associated therewith in suicide attempters who required psychiatric emergency treatment.

    Authors: Kotaro Otsuka, Hikaru Nakamura, Kaoru Kudo, Jin Endo, Katsumi Sanjo, Kentaro Fukumoto, Katsuhito Hoshi, Junko Yagi and Akio Sakai

    Citation: Annals of General Psychiatry 2015 14:48

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  3. Content type: Primary research

    It still remains unclear whether non-suicidal self-injury (NSSI) in young adult populations represents an actual symptom leading to psychiatric illness, constitutes a disorder itself or is rather a cultural pe...

    Authors: Rachel Stroehmer, Marc A. Edel, Steffi Pott, Georg Juckel and Ida S. Haussleiter

    Citation: Annals of General Psychiatry 2015 14:47

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  4. Content type: Primary research

    The relationship between violence and neurocognitive function in schizophrenia is unclear. We examined the backgrounds and neurocognitive functions of violent and nonviolent patients with schizophrenia to iden...

    Authors: Hiroko Kashiwagi, Noriomi Kuroki, Satoru Ikezawa, Masateru Matsushita, Masanori Ishikawa, Kazuyuki Nakagome, Naotsugu Hirabayashi and Manabu Ikeda

    Citation: Annals of General Psychiatry 2015 14:46

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  5. Content type: Primary research

    We have shown that serotonin transporter (SERT) clustering in blood lymphocytes is altered in major depression and correlates with pharmacological therapeutic responses measured with the Hamilton scale. In the...

    Authors: Tania Rivera-Baltanas, Roberto Carlos Agis-Balboa, Raquel Romay-Tallon, Lisa E. Kalynchuk, Jose Manuel Olivares and Hector J. Caruncho

    Citation: Annals of General Psychiatry 2015 14:45

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  6. Content type: Primary research

    A high prevalence of cannabis use disorder has been reported in subjects suffering from schizophrenia, fuelling intense debate about whether schizophrenia with pre-onset cannabis use disorder may be a distinc...

    Authors: Samuel Sarrazin, Florence Louppe, Raphael Doukhan and Franck Schürhoff

    Citation: Annals of General Psychiatry 2015 14:44

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  7. Content type: Primary research

    The aim of the aricle is to study the relationship between attachment, parental rearing behavior, and (infant and current) ADHD symptoms with emotion processing and alexithymia in adults with ADHD.

    Authors: Marc-Andreas Edel, Susanne Edel, Marie Krüger, Hans-Jörg Assion, Georg Juckel and Martin Brüne

    Citation: Annals of General Psychiatry 2015 14:43

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  8. Content type: Primary research

    Bipolar disorder is a chronic mood disorder with episodic progress and high relapse rate. Growing evidence suggests that individuals with bipolar disorder display cognitive impairment which persists even throu...

    Authors: Mădălina Vrabie, Victor Marinescu, Anca Talaşman, Oana Tăutu, Eduard Drima and Ioana Micluţia

    Citation: Annals of General Psychiatry 2015 14:41

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  9. Content type: Primary research

    Schizophrenia is a chronic mental disorder that leads to disability in several aspects of the individual’s personal, social, and occupational functioning. This study assesses and compares the level of disabili...

    Authors: Adesanmi Akinsulore, Boladale M. Mapayi, Olutayo O. Aloba, Ibidunni Oloniniyi, Femi O. Fatoye and Roger O. A. Makanjuola

    Citation: Annals of General Psychiatry 2015 14:40

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  10. Content type: Primary research

    Clozapine is widely prescribed and, although effective, can cause weight gain and dysglycemia. The dysmetabolic effects of clozapine are thought to be more prevalent in women with this gender on average attain...

    Authors: Simon G. Anderson, Mark Livingston, Lewis Couchman, Daniel J. Smith, Moira Connolly, Joan Miller, Robert J. Flanagan and A. H. Heald

    Citation: Annals of General Psychiatry 2015 14:39

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  11. Content type: Case Report

    To the best of our knowledge, there are no case studies of serotonin syndrome (SS) in patients with autism spectrum disorder. We report the case of a 33-year-old male who presented SS under the combined use of...

    Authors: Kalliopi N. Nikolaou, Rossetos Gournellis, Ioannis Michopoulos, Georgios Dervenoulas, Christos Christodoulou and Athanasios Douzenis

    Citation: Annals of General Psychiatry 2015 14:38

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  12. Content type: Primary research

    Rapid advances in information technology and telecommunications have resulted in a dramatic increase in the use of mobile devices and the internet to enhance and facilitate access to treatment. Cognitive beha...

    Authors: Kenneth A. Kobak, James C. Mundt and Betsy Kennard

    Citation: Annals of General Psychiatry 2015 14:37

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    The Erratum to this article has been published in Annals of General Psychiatry 2016 15:2

  13. Content type: Primary research

    A number of studies have reported that smoking rates are higher and smoking cessation rates are lower in patients with mental disorders than in the general population. Despite the harmful effects of smoking, i...

    Authors: Kazumichi Hashimoto, Manabu Makinodan, Yasuhiro Matsuda, Tsubasa Morimoto, Shotaro Ueda and Toshifumi Kishimoto

    Citation: Annals of General Psychiatry 2015 14:35

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  14. Content type: Primary research

    Erectile dysfunction (ED) and premature ejaculation (PE) are the two most prevalent sexual disorders among males associated with significant distress and impairment in quality of life. The aim of this study wa...

    Authors: Iraklis Mourikis, Marianthi Antoniou, Efi Matsouka, Eleni Vousoura, Chara Tzavara, Chrysa Ekizoglou, George N. Papadimitriou, Nikos Vaidakis and Iannis M. Zervas

    Citation: Annals of General Psychiatry 2015 14:34

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  15. Content type: Primary research

    Although mood disorders and cardiovascular diseases have widely studied psychosomatic connections, data concerning the influence of the psychopathologically important affective temperaments in hypertension are...

    Authors: Andrea László, Levente Babos, Zsóka Kis-Igari, Adrienn Pálfy, Péter Torzsa, Ajándék Eőry, László Kalabay, Xenia Gonda, Zoltán Rihmer, Orsolya Cseprekál, András Tislér, Judit Hodrea, Lilla Lénárt, Andrea Fekete and János Nemcsik

    Citation: Annals of General Psychiatry 2015 14:33

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  16. Content type: Primary research

    Cognitive functions have been investigated across depressed, manic, hypomanic, mixed and euthymic episodes of bipolar disorder, but the stability or the progression of cognitive impairment is still under resea...

    Authors: Ramona Păunescu and Ioana Micluţia

    Citation: Annals of General Psychiatry 2015 14:32

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  17. Content type: Primary research

    Several studies have raised concerns over consequences of brand-to-generic and generic-to-generic pharmacy-generated medication substitutions in psychiatric and non-psychiatric patients. The purpose of this re...

    Authors: Slawomir Murawiec, Aleksandra Rajewska-Rager, Jerzy Samochowiec, Sylwia Kalinowska, Jacek Kurpisz, Joanna Krzyzanowska, Halina Sienkiewicz-Jarosz, Iwona Kurkowska-Jastrzebska, Agnieszka Samochowiec and Przemyslaw Bienkowski

    Citation: Annals of General Psychiatry 2015 14:31

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  18. Content type: Primary research

    As a neurotoxic substance, alcohol can induce neurodegenesis in the brain. Alcohol-dependent patients’ cognitive functioning can be affected by chronic alcohol use. In addition, brain-derived neurotrophic fact...

    Authors: Changwoo Han, Hwallip Bae, Sung-Doo Won, Sungwon Roh and Dai-Jin Kim

    Citation: Annals of General Psychiatry 2015 14:30

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  19. Content type: Primary research

    Multiple sclerosis is increasingly becoming a major health problem among women worldwide. The aim of the present study was to estimate prevalence of depression in women with multiple sclerosis and also to iden...

    Authors: Khadijeh Mohammadi, Parvin Rahnama and Ali Montazeri

    Citation: Annals of General Psychiatry 2015 14:29

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  20. Content type: Primary research

    Robert Cloninger’s psychobiological model of temperament and character is a dimensional approach to personality assessment and gave birth to the temperament and character inventory (TCI). The aim of the presen...

    Authors: Konstantinos N. Fountoulakis, Sandor Rozsa, Melina Siamouli, Katerina Moutou, Eleonora Pantoula and Claude Robert Cloninger

    Citation: Annals of General Psychiatry 2015 14:28

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  21. Content type: Review

    The disability and burden associated with major depression comes only in part from its affective symptoms; cognitive dysfunctions associated with depression also play a crucial role. Furthermore, these cogniti...

    Authors: Xenia Gonda, Maurizio Pompili, Gianluca Serafini, Andre F. Carvalho, Zoltan Rihmer and Peter Dome

    Citation: Annals of General Psychiatry 2015 14:27

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  22. Content type: Primary research

    Open-label quetiapine coadministration with SSRI therapy, in a diagnostically mixed sample of comorbid anxiety patients, offered additional anxiolytic benefit. Therefore, we designed the following controlled t...

    Authors: Andrew W. Goddard, Waqar Mahmud, Carla Medlock, Yong-Wook Shin and Anantha Shekhar

    Citation: Annals of General Psychiatry 2015 14:26

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  23. Content type: Primary research

    Experimenter’s allegiance (EA) refers to a personal confidence of the superiority of a specific psychotherapy treatment. This factor has been linked with larger treatment effects in favor of the preferred trea...

    Authors: Elena Dragioti, Ioannis Dimoliatis, Konstantinos N. Fountoulakis and Evangelos Evangelou

    Citation: Annals of General Psychiatry 2015 14:25

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  24. Content type: Primary research

    Anhedonia is a prominent symptom of major depressive disorder (MDD) and schizophrenia. At present, it is believed that hedonic processing rather consists of the anticipatory and consummatory phase. The aim of ...

    Authors: Yinghui Li, Xiaodong Mou, Wenhao Jiang, Zhong Yang, Xinhua Shen, Zhuma Jin, Zhiping Dai, Yuju Liu, Shengqin Mao, Jian Zhang and Yonggui Yuan

    Citation: Annals of General Psychiatry 2015 14:24

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  25. Content type: Primary research

    A management tool, called the Experience Feedback Committee, has been applied for patient safety and successfully used in medical departments. The purpose of this study was to analyse the functioning of an Exp...

    Authors: Bastien Boussat, Thierry Bougerol, Olivier Detante, Arnaud Seigneurin and Patrice François

    Citation: Annals of General Psychiatry 2015 14:23

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  26. Content type: Case report

    A 40-year-old mentally retarded Japanese man was admitted at rehabilitation facility for handicapped persons and found dead in his bed. His neonatal period was complicated by seizures, and he had a medical his...

    Authors: Hiroyuki Tokue, Yoichiro Takahashi, Satoshi Hirasawa, Sachiko Awata, Susumu Kobayashi, Takehiro Shimada, Azusa Tokue, Rie Sano, Yoshihiko Kominato and Yoshito Tsushima

    Citation: Annals of General Psychiatry 2015 14:22

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  27. Content type: Primary research

    Because little is known about food insecurity in people with mental health conditions, we investigated relationships among food insecurity, nutrient intakes, and psychological functioning in adults with mood d...

    Authors: Karen M Davison and Bonnie J Kaplan

    Citation: Annals of General Psychiatry 2015 14:21

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  28. Content type: Primary research

    Instability of affects and interpersonal relations are important features of borderline personality disorder (BPD). Interpersonal problems of individuals suffering from BPD might develop based on abnormalities...

    Authors: Uta-Susan Donges, Bibiana Dukalski, Anette Kersting and Thomas Suslow

    Citation: Annals of General Psychiatry 2015 14:20

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  29. Content type: Review

    Bipolar disorder (BD) is a chronic disorder with a high relapse rate, significant general disability and burden and with a psychosocial impairment that often persists despite pharmacotherapy. This indicates th...

    Authors: Stella Miziou, Eirini Tsitsipa, Stefania Moysidou, Vangelis Karavelas, Dimos Dimelis, Vagia Polyzoidou and Konstantinos N Fountoulakis

    Citation: Annals of General Psychiatry 2015 14:19

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  30. Content type: Primary research

    In cases of untreated schizophrenia, the patients’ entourage often does not recognize the psychotic symptoms of the patient and the possibility that the patient may attempt suicide. The aim of this study was t...

    Authors: Taiju Yamaguchi, Chiyo Fujii, Takahiro Nemoto, Naohisa Tsujino, Kiyoaki Takeshi and Masafumi Mizuno

    Citation: Annals of General Psychiatry 2015 14:17

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  31. Content type: Primary research

    Prevalence rates of human immunodeficiency virus (HIV) infection among the youth are disproportionately high compared to that of other age groups in Kenya. Poor mental health has been linked to risky HIV behav...

    Authors: Caleb J Othieno, Roselyne Okoth, Karl Peltzer, Supa Pengpid and Lucas O Malla

    Citation: Annals of General Psychiatry 2015 14:16

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  32. Content type: Review

    Loxapine is an antipsychotic used in psychiatry for over 40 years with a well-established profile. Loxapine is a dibenzoxazepine tricyclic antipsychotic agent, available for oral, intramuscular and inhalatory ...

    Authors: Dina Popovic, Philippe Nuss and Eduard Vieta

    Citation: Annals of General Psychiatry 2015 14:15

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  33. Content type: Primary research

    When treating mentally ill criminal offenders, improving medication adherence is essential to achieving goals, such as long-term stabilization of symptoms and the prevention of recidivism. Most subjects who ar...

    Authors: Kenji Murasugi, Teruomi Tsukahara and Shinsuke Washizuka

    Citation: Annals of General Psychiatry 2015 14:11

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  34. Content type: Primary research

    The purpose of the study was to examine the impact of computerized cognitive behavior therapy (CBT) self-help treatment for obsessive-compulsive disorder (OCD) (BT Steps) both alone and when supported by coach...

    Authors: Kenneth A Kobak, Revere Greist, David M Jacobi, Hollie Levy-Mack and John H Greist

    Citation: Annals of General Psychiatry 2015 14:10

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  35. Content type: Primary research

    Repetitive transcranial magnetic stimulation (rTMS) has been found to be effective in reducing frequency and duration of auditory verbal hallucinations (AVH). Priming stimulation, which involves high-frequency...

    Authors: Prasenjit Ray, Vinod Kumar Sinha and Sai Krishna Tikka

    Citation: Annals of General Psychiatry 2015 14:8

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  36. Content type: Review

    Dromokaition Psychiatric Hospital opened its doors in 1887, following the donation made by Zorzis Dromokaitis from the island of Chios. Private donations and all forms of charities had contributed to a large e...

    Authors: Markella Fiste, Dimitrios Ploumpidis, Costas Tsiamis, Effie Poulakou-Rebelakou and Ioannis Liappas

    Citation: Annals of General Psychiatry 2015 14:7

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  37. Content type: Primary research

    This study aimed to compare the performance of Positive and Negative Syndrome Scale (PANSS) symptom severity criteria established by the Remission in Schizophrenia Working Group (RSWG) with criteria based on C...

    Authors: Federica Pinna, Luca Deriu, Enrica Diana, Valeria Perra, Rachele Pisu Randaccio, Lucia Sanna, Massimo Tusconi and Bernardo Carpiniello

    Citation: Annals of General Psychiatry 2015 14:6

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  38. Content type: Primary research

    Trauma exposure depends of the type of trauma and can result in the development of posttraumatic stress disorder (PTSD). The type of traumatization (such as Holocaust experiences and other sources of trauma) a...

    Authors: Helge H Müller, Sebastian Moeller, York Hilger and Wolfgang Sperling

    Citation: Annals of General Psychiatry 2015 14:5

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  39. Content type: Primary research

    Despite the fact that smoking is a crucial morbidity factor among psychiatric patients, little progress has been made in order to reduce smoking during psychiatric hospitalization.

    Authors: Ioannis Michopoulos, Emmanouil Rizos, Rossetos Gournellis, Andromachi Karvouni, Ioanna Kotsioumpa and Athanasios Douzenis

    Citation: Annals of General Psychiatry 2015 14:4

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  40. Content type: Primary research

    Under-prescription of antidepressants (ADs) among people meeting the criteria for major depressive episodes and excessive prescription in less symptomatic patients have been reported. The reasons influencing g...

    Authors: Alain Mercier, Jacques Benichou, Isabelle Auger-Aubin, Jean-Pierre Lebeau, Estelle Houivet, Paul Van Royen and Lieve Peremans

    Citation: Annals of General Psychiatry 2015 14:3

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  41. Content type: Review

    This study is done to compare the effect of adjunctive therapy with pregabalin versus usual care (UC) on health-care costs and clinical and patients consequences in generalized anxiety disorder (GAD) subjects ...

    Authors: Enrique Álvarez, José M Olivares, José L Carrasco, Vanessa López-Gómez and Javier Rejas

    Citation: Annals of General Psychiatry 2015 14:2

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  42. Content type: Primary research

    While the frequency and importance of antipsychotic switching in patients with schizophrenia, there is insufficient evidence with regard to switching strategy. Quetiapine is one of the drugs of choice for swit...

    Authors: Naoki Hashimoto, Atsuhito Toyomaki, Minoru Honda, Satoru Miyano, Nobuyuki Nitta, Hiroyuki Sawayama, Yasufumi Sugawara, Keiichi Uemura, Noriko Tsukamoto, Tsukasa Koyama and Ichiro Kusumi

    Citation: Annals of General Psychiatry 2015 14:1

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  43. Content type: Primary research

    Alexithymia, the difficulty in describing or recognizing emotions, has been associated with various psychosomatic pathologies including psoriasis. The aim of this study was to examine the prevalence of alexith...

    Authors: Panagiota Korkoliakou, Christos Christodoulou, Anargyros Kouris, Evgenia Porichi, Vasiliki Efstathiou, Eythymia Kaloudi, Anna Kokkevi, Nikolaos Stavrianeas, Charalabos Papageorgiou and Athanasios Douzenis

    Citation: Annals of General Psychiatry 2014 13:38

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