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  1. A specific psychopathology of addiction has been proposed and described using the self-report symptom inventory (SCL-90), leading to a 5-factor aggregation of psychological/psychiatric symptoms: ‘worthlessness...

    Authors: Angelo G. I. Maremmani, Pier Paolo Pani, Emanuela Trogu, Federica Vigna-Taglianti, Federica Mathis, Roberto Diecidue, Ursula Kirchmayer, Laura Amato, Joli Ghibaudi, Antonella Camposeragna, Alessio Saponaro, Marina Davoli, Fabrizio Faggiano and Icro Maremmani

    Citation: Annals of General Psychiatry 2016 15:29

    Content type: Primary research

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  2. Previous studies have shown that personality characteristics affect sexual functioning. The aim of this exploratory study was to assess and describe the relationship between global personality traits and the s...

    Authors: Jacek Kurpisz, Monika Mak, Michał Lew-Starowicz, Krzysztof Nowosielski, Przemysław Bieńkowski, Robert Kowalczyk, Błażej Misiak, Dorota Frydecka and Jerzy Samochowiec

    Citation: Annals of General Psychiatry 2016 15:28

    Content type: Primary research

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  3. This study aimed to evaluate whether selecting mirtazapine as the first choice for current depressive episode instead of selective serotonin reuptake inhibitors (SSRIs) reduces benzodiazepine use in patients w...

    Authors: Tasuku Hashimoto, Akihiro Shiina, Tadashi Hasegawa, Hiroshi Kimura, Yasunori Oda, Tomihisa Niitsu, Masatomo Ishikawa, Masumi Tachibana, Katsumasa Muneoka, Satoshi Matsuki, Michiko Nakazato and Masaomi Iyo

    Citation: Annals of General Psychiatry 2016 15:27

    Content type: Primary research

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  4. Orbitofrontal cortex alterations have been suggested to underlie the impaired mood regulation in depression. MAOA-uVNTR (monoamine oxidase A-upstream variable number of tandem repeats) polymorphism has been repor...

    Authors: Eunsoo Won, Sunyoung Choi, June Kang, Min-Soo Lee and Byung-Joo Ham

    Citation: Annals of General Psychiatry 2016 15:26

    Content type: Primary research

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  5. Quality of life can be perceived as a subjective assessment of different aspects of human functioning. Personality is a factor which determines actions taken by individuals and their tendency to perceive reali...

    Authors: Daria Schneider-Matyka, Anna Jurczak, Agnieszka Samochowiec, Beata Karakiewicz, Małgorzata Szkup, Anna Grzywacz and Elżbieta Grochans

    Citation: Annals of General Psychiatry 2016 15:25

    Content type: Primary research

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  6. Alterations in one-carbon metabolism (OCM) have been observed in patients with schizophrenia (SZ), but a comprehensive study of OCM has not yet been conducted. A carbon atom is transferred from l-serine to methio...

    Authors: Yumiko Takano, Yuji Ozeki, Masae Sekine, Kumiko Fujii, Takashi Watanabe, Hiroaki Okayasu, Takahiro Shinozaki, Akiko Aoki, Kazufumi Akiyama, Hiroshi Homma and Kazutaka Shimoda

    Citation: Annals of General Psychiatry 2016 15:23

    Content type: Primary research

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  7. The objective of this study was to describe the profile and alcoholic status of a population with alcohol use disorders (AUD) requesting help from a psychiatric hospital to stop drinking, as well as their clin...

    Authors: Philippe Nubukpo, Murielle Girard, Jean-Marie Sengelen, Sophie Bonnefond, Aurélien Varnoux, Benoît Marin and Dominique Malauzat

    Citation: Annals of General Psychiatry 2016 15:22

    Content type: Primary research

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  8. Longer treatment duration is important for the successful treatment of gambling disorder (GD). This retrospective study investigated the factors and interventions that might enhance treatment duration in GD p...

    Authors: Sam-Wook Choi, Young-Chul Shin, HyunChul Youn, Se-Won Lim and Juwon Ha

    Citation: Annals of General Psychiatry 2016 15:20

    Content type: Primary research

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  9. It is well known that suicidal rates vary considerably among European countries and the reasons for this are unknown, although several theories have been proposed. The effect of economic variables has been ext...

    Authors: Konstantinos N. Fountoulakis, Isaia Chatzikosta, Konstantinos Pastiadis, Prodromos Zanis, Wolfram Kawohl, Ad J. F. M. Kerkhof, Alvydas Navickas, Cyril Höschl, Dusica Lecic-Tosevski, Eliot Sorel, Elmars Rancans, Eva Palova, Georg Juckel, Goran Isacsson, Helena Korosec Jagodic, Ileana Botezat-Antonescu…

    Citation: Annals of General Psychiatry 2016 15:19

    Content type: Primary research

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  10. Major depressive disorder (MDD) is a common psychiatric disorder with considerable mortality. Death from unnatural causes, largely suicidal or quasi-suicidal, has a particularly high risk for the functional di...

    Authors: Mohamed Amine Sayadi, Ons Achour, Asma Ezzaher, Ilham Hellara, Asma Omezzine, Wahiba Douki, Ali Bousslama, Lotfi Gaha and Mohamed Fadhel Najjar

    Citation: Annals of General Psychiatry 2016 15:18

    Content type: Primary research

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  11. Brain-derived neurotrophic factor (BDNF) has neuroprotective, proangiogenic and myogenic effects and, therefore, possibly acts as a psychosomatic mediator. Here, we measured serum BDNF (seBDNF) level in hypert...

    Authors: János Nemcsik, Andrea László, Lilla Lénárt, Dániel Eörsi, Péter Torzsa, Beáta Kőrösi, Orsolya Cseprekál, András Tislér, Ádám Tabák, Xenia Gonda, Zoltán Rihmer, Judit Hodrea, Zsófia Nemcsik-Bencze and Andrea Fekete

    Citation: Annals of General Psychiatry 2016 15:17

    Content type: Primary research

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  12. Investing in financial markets is promoted and protected by the government as an essential economic activity, but can turn into a gambling addiction problem. Until now, few scales have widely been used to iden...

    Authors: HyunChul Youn, Jung-Seok Choi, Dai-Jin Kim and Sam-Wook Choi

    Citation: Annals of General Psychiatry 2016 15:16

    Content type: Primary research

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  13. Conflicting evidence exists about the relationship between psychotic symptoms and suicidality in mood disorders. We aimed to investigate the lifetime suicidality and its relationship with dimensions of the psy...

    Authors: Camilla Gesi, Claudia Carmassi, Mario Miniati, Antonella Benvenuti, Gabriele Massimetti and Liliana Dell’Osso

    Citation: Annals of General Psychiatry 2016 15:15

    Content type: Primary research

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  14. The relationship between mental stress and cardiovascular disease has been shown in several studies. Panic disorder (PD) is also associated with cardiovascular disease due to increased risk of myocardial infar...

    Authors: Omer Yanartas, Murat Sunbul, Zeynep Senkal, Erdal Durmus, Tarik Kivrak, Nilufer Subasi, Gulhan Karaer, Serhat Ergun, Ibrahim Sari and Kemal Sayar

    Citation: Annals of General Psychiatry 2016 15:14

    Content type: Primary research

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  15. We previously found a five cluster of psychological symptoms in heroin use disorder (HUD) patients: ‘worthlessness-being trapped’, ‘somatic-symptoms’, ‘sensitivity-psychoticism’, ‘panic-anxiety’, and ‘violence...

    Authors: Pier Paolo Pani, Angelo G. I. Maremmani, Emanuela Trogu, Federica Vigna-Taglianti, Federica Mathis, Roberto Diecidue, Ursula Kirchmayer, Laura Amato, Joli Ghibaudi, Antonella Camposeragna, Alessio Saponaro, Marina Davoli, Fabrizio Faggiano and Icro Maremmani

    Citation: Annals of General Psychiatry 2016 15:13

    Content type: Primary research

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  16. Approximately one-third of stroke survivors suffer from post-stroke depression (PSD) in the acute or chronic stages. The presence of PSD in the acute stage after stroke is reportedly associated with poor patie...

    Authors: Norifumi Metoki, Norio Sugawara, Joji Hagii, Shin Saito, Hiroshi Shiroto, Tetsu Tomita, Minoru Yasujima, Ken Okumura and Norio Yasui-Furukori

    Citation: Annals of General Psychiatry 2016 15:12

    Content type: Primary research

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  17. Beck’s cognitive theory postulates that dysfunctional attitudes predisposing to depression are formed by early negative experiences. Meanwhile, Bowlby’s attachment theory contends that distorted working models...

    Authors: Koichi Otani, Akihito Suzuki, Yoshihiko Matsumoto and Masanori Enokido

    Citation: Annals of General Psychiatry 2016 15:11

    Content type: Primary research

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  18. The character higher order scales (self-directedness, cooperativeness, and self-transcendence) in the temperament and character inventory are important general measures of health and well-being [Mens Sana Mono...

    Authors: Nigel Lester, Danilo Garcia, Sebastian Lundström, Sven Brändström, Maria Råstam, Nóra Kerekes, Thomas Nilsson, C. Robert Cloninger and Henrik Anckarsäter

    Citation: Annals of General Psychiatry 2016 15:10

    Content type: Primary research

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  19. Bipolar I and II represent the most common and severe subtypes of bipolar disorder. Although bipolar I disorder is relatively well studied, the clinical characteristics and response to treatment of patients wi...

    Authors: Catherine Datto, William J. Pottorf, Louisa Feeley, Scott LaPorte and Charlie Liss

    Citation: Annals of General Psychiatry 2016 15:9

    Content type: Primary research

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  20. The Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) recently included sensory processing abnormalities in the diagnostic criteria for individuals with autism spectrum disorder (ASD)...

    Authors: Yuka Yasuda, Ryota Hashimoto, Aya Nakae, Hongling Kang, Kazutaka Ohi, Hidenaga Yamamori, Michiko Fujimoto, Satoshi Hagihira and Masatoshi Takeda

    Citation: Annals of General Psychiatry 2016 15:8

    Content type: Primary research

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  21. The arduous emotional and physical nurses’ work, the gradual nursing staff cutbacks and the lack of recognition that nurses feel regarding their skills and overall capabilities are some of the factors that act...

    Authors: Christina Karatza, Sofia Zyga, Styliani Tziaferi and Panagiotis Prezerakos

    Citation: Annals of General Psychiatry 2016 15:7

    Content type: Primary research

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  22. Lamotrigine is an effective anticonvulsant drug that has also been demonstrated to be effective in the treatment of bipolar disorder. We report a case of rhabdomyolysis after intentional overdose in a woman ag...

    Authors: Sokratis E. Karaoulanis, Markos Syngelakis and Konstantinos Fokas

    Citation: Annals of General Psychiatry 2016 15:6

    Content type: Case Report

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  23. One of the major factors affecting treatment compliance and outcome in patients is the wide range of side effects (SEs) associated with antidepressants. In the present study, we aimed to assess the extent to w...

    Authors: Uri Nitzan, Tal Bekerman, Gideon Becker, Pesach Lichtenberg, Shaul Lev-Ran, Garry Walter, Hagai Maoz and Yuval Bloch

    Citation: Annals of General Psychiatry 2016 15:5

    Content type: Primary research

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  24. It is often difficult to differentiate between the depressive states seen in late-life depression and late-onset Alzheimer’ disease (AD) in the clinical setting.

    Authors: Yoshiaki Tsuruoka, Michio Takahashi, Masatoshi Suzuki, Koichi Sato and Yukihiko Shirayama

    Citation: Annals of General Psychiatry 2016 15:3

    Content type: Primary research

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  25. We investigated the serum levels of brain-derived neurotrophic factor (BDNF), proBDNF and plasma 3-methoxy-4-hydroxyphenylglycol (MHPG) levels in patients with chronic schizophrenia.

    Authors: Reiji Yoshimura, Hikaru Hori, Asuka Katsuki, Kiyokazu Atake and Jun Nakamura

    Citation: Annals of General Psychiatry 2016 15:1

    Content type: Primary research

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  26. To determine the timing of development of suicidal ideation and factors associated therewith in suicide attempters who required psychiatric emergency treatment.

    Authors: Kotaro Otsuka, Hikaru Nakamura, Kaoru Kudo, Jin Endo, Katsumi Sanjo, Kentaro Fukumoto, Katsuhito Hoshi, Junko Yagi and Akio Sakai

    Citation: Annals of General Psychiatry 2015 14:48

    Content type: Primary Research

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  27. It still remains unclear whether non-suicidal self-injury (NSSI) in young adult populations represents an actual symptom leading to psychiatric illness, constitutes a disorder itself or is rather a cultural pe...

    Authors: Rachel Stroehmer, Marc A. Edel, Steffi Pott, Georg Juckel and Ida S. Haussleiter

    Citation: Annals of General Psychiatry 2015 14:47

    Content type: Primary research

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  28. The relationship between violence and neurocognitive function in schizophrenia is unclear. We examined the backgrounds and neurocognitive functions of violent and nonviolent patients with schizophrenia to iden...

    Authors: Hiroko Kashiwagi, Noriomi Kuroki, Satoru Ikezawa, Masateru Matsushita, Masanori Ishikawa, Kazuyuki Nakagome, Naotsugu Hirabayashi and Manabu Ikeda

    Citation: Annals of General Psychiatry 2015 14:46

    Content type: Primary research

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  29. We have shown that serotonin transporter (SERT) clustering in blood lymphocytes is altered in major depression and correlates with pharmacological therapeutic responses measured with the Hamilton scale. In the...

    Authors: Tania Rivera-Baltanas, Roberto Carlos Agis-Balboa, Raquel Romay-Tallon, Lisa E. Kalynchuk, Jose Manuel Olivares and Hector J. Caruncho

    Citation: Annals of General Psychiatry 2015 14:45

    Content type: Primary research

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  30. A high prevalence of cannabis use disorder has been reported in subjects suffering from schizophrenia, fuelling intense debate about whether schizophrenia with pre-onset cannabis use disorder may be a distinc...

    Authors: Samuel Sarrazin, Florence Louppe, Raphael Doukhan and Franck Schürhoff

    Citation: Annals of General Psychiatry 2015 14:44

    Content type: Primary research

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  31. The aim of the aricle is to study the relationship between attachment, parental rearing behavior, and (infant and current) ADHD symptoms with emotion processing and alexithymia in adults with ADHD.

    Authors: Marc-Andreas Edel, Susanne Edel, Marie Krüger, Hans-Jörg Assion, Georg Juckel and Martin Brüne

    Citation: Annals of General Psychiatry 2015 14:43

    Content type: Primary research

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  32. Bipolar disorder is a chronic mood disorder with episodic progress and high relapse rate. Growing evidence suggests that individuals with bipolar disorder display cognitive impairment which persists even throu...

    Authors: Mădălina Vrabie, Victor Marinescu, Anca Talaşman, Oana Tăutu, Eduard Drima and Ioana Micluţia

    Citation: Annals of General Psychiatry 2015 14:41

    Content type: Primary research

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  33. Schizophrenia is a chronic mental disorder that leads to disability in several aspects of the individual’s personal, social, and occupational functioning. This study assesses and compares the level of disabili...

    Authors: Adesanmi Akinsulore, Boladale M. Mapayi, Olutayo O. Aloba, Ibidunni Oloniniyi, Femi O. Fatoye and Roger O. A. Makanjuola

    Citation: Annals of General Psychiatry 2015 14:40

    Content type: Primary research

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  34. Clozapine is widely prescribed and, although effective, can cause weight gain and dysglycemia. The dysmetabolic effects of clozapine are thought to be more prevalent in women with this gender on average attain...

    Authors: Simon G. Anderson, Mark Livingston, Lewis Couchman, Daniel J. Smith, Moira Connolly, Joan Miller, Robert J. Flanagan and A. H. Heald

    Citation: Annals of General Psychiatry 2015 14:39

    Content type: Primary research

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  35. To the best of our knowledge, there are no case studies of serotonin syndrome (SS) in patients with autism spectrum disorder. We report the case of a 33-year-old male who presented SS under the combined use of...

    Authors: Kalliopi N. Nikolaou, Rossetos Gournellis, Ioannis Michopoulos, Georgios Dervenoulas, Christos Christodoulou and Athanasios Douzenis

    Citation: Annals of General Psychiatry 2015 14:38

    Content type: Case Report

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  36. Rapid advances in information technology and telecommunications have resulted in a dramatic increase in the use of mobile devices and the internet to enhance and facilitate access to treatment. Cognitive beha...

    Authors: Kenneth A. Kobak, James C. Mundt and Betsy Kennard

    Citation: Annals of General Psychiatry 2015 14:37

    Content type: Primary research

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    The Erratum to this article has been published in Annals of General Psychiatry 2016 15:2

  37. A number of studies have reported that smoking rates are higher and smoking cessation rates are lower in patients with mental disorders than in the general population. Despite the harmful effects of smoking, i...

    Authors: Kazumichi Hashimoto, Manabu Makinodan, Yasuhiro Matsuda, Tsubasa Morimoto, Shotaro Ueda and Toshifumi Kishimoto

    Citation: Annals of General Psychiatry 2015 14:35

    Content type: Primary research

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  38. Erectile dysfunction (ED) and premature ejaculation (PE) are the two most prevalent sexual disorders among males associated with significant distress and impairment in quality of life. The aim of this study wa...

    Authors: Iraklis Mourikis, Marianthi Antoniou, Efi Matsouka, Eleni Vousoura, Chara Tzavara, Chrysa Ekizoglou, George N. Papadimitriou, Nikos Vaidakis and Iannis M. Zervas

    Citation: Annals of General Psychiatry 2015 14:34

    Content type: Primary research

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  39. Although mood disorders and cardiovascular diseases have widely studied psychosomatic connections, data concerning the influence of the psychopathologically important affective temperaments in hypertension are...

    Authors: Andrea László, Levente Babos, Zsóka Kis-Igari, Adrienn Pálfy, Péter Torzsa, Ajándék Eőry, László Kalabay, Xenia Gonda, Zoltán Rihmer, Orsolya Cseprekál, András Tislér, Judit Hodrea, Lilla Lénárt, Andrea Fekete and János Nemcsik

    Citation: Annals of General Psychiatry 2015 14:33

    Content type: Primary research

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  40. Cognitive functions have been investigated across depressed, manic, hypomanic, mixed and euthymic episodes of bipolar disorder, but the stability or the progression of cognitive impairment is still under resea...

    Authors: Ramona Păunescu and Ioana Micluţia

    Citation: Annals of General Psychiatry 2015 14:32

    Content type: Primary research

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  41. Several studies have raised concerns over consequences of brand-to-generic and generic-to-generic pharmacy-generated medication substitutions in psychiatric and non-psychiatric patients. The purpose of this re...

    Authors: Slawomir Murawiec, Aleksandra Rajewska-Rager, Jerzy Samochowiec, Sylwia Kalinowska, Jacek Kurpisz, Joanna Krzyzanowska, Halina Sienkiewicz-Jarosz, Iwona Kurkowska-Jastrzebska, Agnieszka Samochowiec and Przemyslaw Bienkowski

    Citation: Annals of General Psychiatry 2015 14:31

    Content type: Primary research

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  42. As a neurotoxic substance, alcohol can induce neurodegenesis in the brain. Alcohol-dependent patients’ cognitive functioning can be affected by chronic alcohol use. In addition, brain-derived neurotrophic fact...

    Authors: Changwoo Han, Hwallip Bae, Sung-Doo Won, Sungwon Roh and Dai-Jin Kim

    Citation: Annals of General Psychiatry 2015 14:30

    Content type: Primary research

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  43. Multiple sclerosis is increasingly becoming a major health problem among women worldwide. The aim of the present study was to estimate prevalence of depression in women with multiple sclerosis and also to iden...

    Authors: Khadijeh Mohammadi, Parvin Rahnama and Ali Montazeri

    Citation: Annals of General Psychiatry 2015 14:29

    Content type: Primary research

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  44. The disability and burden associated with major depression comes only in part from its affective symptoms; cognitive dysfunctions associated with depression also play a crucial role. Furthermore, these cogniti...

    Authors: Xenia Gonda, Maurizio Pompili, Gianluca Serafini, Andre F. Carvalho, Zoltan Rihmer and Peter Dome

    Citation: Annals of General Psychiatry 2015 14:27

    Content type: Review

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