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  1. Content type: Primary research

    Although the promotion of mental health (MHP) through education and training is widely accepted, there is scarce evidence for its effectiveness in the literature from outcome studies worldwide. The present stu...

    Authors: Vlassis D Tomaras, Maria Ginieri-Coccossis, Maria Vassiliadou, Melpomeni Malliori, Spyros Ferentinos, Constantin R Soldatos and Andre Tylee

    Citation: Annals of General Psychiatry 2011 10:33

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  2. Content type: Primary research

    Several studies have reported high prevalence of anxiety and depression in chronic obstructive pulmonary disease (COPD) outpatients. Moreover, these patients share psychological or psychopathological character...

    Authors: Athanasios Tselebis, Dionisios Bratis, Epaminondas Kosmas, Maria Harikiopoulou, Elpida Theodorakopoulou, Silvia Dumitru, Georgios Moussas, Athanasios Karkanias, Ioannis Ilias, Nikolaos Siafakas, Alexandros Vgontzas and Nikolaos Tzanakis

    Citation: Annals of General Psychiatry 2011 10:32

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  3. Content type: Primary research

    It seems that the core neural regions and cognitive processes implicated in obsessive-compulsive disorder (OCD) pathophysiology may overlap with those involved in humor appreciation. However, to date, there ha...

    Authors: Vasilis P Bozikas, Mary H Kosmidis, Maria Giannakou, Aravela Adamopoulou, Xenia Gonda, Kostas Fokas and George Garyfallos

    Citation: Annals of General Psychiatry 2011 10:31

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  4. Content type: Primary research

    Around 9% to 20% of bereaved individuals experience symptoms of complicated grief (CG) that are associated with significant distress and impairment. A major issue is whether CG represents a distinctive nosogra...

    Authors: Liliana Dell'Osso, Claudia Carmassi, Martina Corsi, Irene Pergentini, Chiara Socci, Angelo GI Maremmani and Giulio Perugi

    Citation: Annals of General Psychiatry 2011 10:29

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  5. Content type: Primary research

    Psychological distress in healthcare workers may vary across different specialties. The purpose of this study was to investigate the differences in the rate of anxiety and depression between medical and mental...

    Authors: Ioanna V Papathanasiou, Dimitrios Damigos and Venetsanos Mavreas

    Citation: Annals of General Psychiatry 2011 10:28

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  6. Content type: Primary research

    Hearing impairment is a prevalent and chronic condition in older people. This study investigated the relationship between cognitive function and hearing impairment in a Japanese population.

    Authors: Norio Sugawara, Akira Sasaki, Norio Yasui-Furukori, Seiji Kakehata, Takashi Umeda, Atsushi Namba, Shigeyuki Nakaji, Hideichi Shinkawa and Sunao Kaneko

    Citation: Annals of General Psychiatry 2011 10:27

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  7. Content type: Case report

    There is emerging evidence that antidepressants may be effective in preventing patients with non-specific and psychotic-like prodromal symptoms, defined as patients at ultra-high risk (UHR) of psychotic disord...

    Authors: Shigenori Tadokoro, Nobuhisa Kanahara, Shuichi Kikuchi, Kenji Hashimoto and Masaomi Iyo

    Citation: Annals of General Psychiatry 2011 10:26

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  8. Content type: Primary research

    Increased prescription of antidepressants has been consistently associated with a decrease in suicide rates in several countries. The aim of this study is to explore antidepressant consumption, suicide rates a...

    Authors: Giuseppe Guaiana, Margherita Andretta, Eric Griez, Bruno Biancosino and Luigi Grassi

    Citation: Annals of General Psychiatry 2011 10:24

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  9. Content type: Primary research

    Despite multiple antidepressant options, major depressive disorder (MDD) still faces high non-response rates, eventually requiring anticonvulsant augmentation strategies too. The aim of this study was to explo...

    Authors: Michele Fornaro, Matteo Martino, Bruna Dalmasso, Salvatore Colicchio, Marzia Benvenuti, Giulio Rocchi, Andrea Escelsior and Giulio Perugi

    Citation: Annals of General Psychiatry 2011 10:23

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  10. Content type: Review

    Awareness of the importance of maintaining physical health for patients with severe mental illnesses has recently been on the increase. Although there are several elements contributing to poor physical health ...

    Authors: Fernando Chacón, Fernando Mora, Alicia Gervás-Ríos and Inmaculada Gilaberte

    Citation: Annals of General Psychiatry 2011 10:22

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  11. Content type: Primary research

    Lifestyle factors, such as an unbalanced diet and lack of physical activity, may affect the prevalence of metabolic syndrome (MetS) in schizophrenic patients. The aim of this study was to compare the MetS prev...

    Authors: Norio Sugawara, Norio Yasui-Furukori, Yasushi Sato, Ikuko Kishida, Hakuei Yamashita, Manabu Saito, Hanako Furukori, Taku Nakagami, Mitsunori Hatakeyama and Sunao Kaneko

    Citation: Annals of General Psychiatry 2011 10:21

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  12. Content type: Primary research

    Over 290,000 patients are undergoing hemodialysis (HD) in Japan. With old age, the odds of undergoing HD treatment sharply increase, as does the prevalence of cognitive impairment. The aim of the present work ...

    Authors: Gen Odagiri, Norio Sugawara, Atsuhiro Kikuchi, Ippei Takahashi, Takashi Umeda, Hisao Saitoh, Norio Yasui-Furukori and Sunao Kaneko

    Citation: Annals of General Psychiatry 2011 10:20

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  13. Content type: Primary research

    Although the 'copy of cube test', a version of which is included in the Short Test of Mental Status (STMS), has existed for years, little has been done to standardize it in detail. The aim of the current study...

    Authors: Konstantinos N Fountoulakis, Melina Siamouli, Stamatia Magiria, Panagiotis T Panagiotidis, Sotiris Kantartzis, Vassiliki A Terzoglou and Timucin Oral

    Citation: Annals of General Psychiatry 2011 10:19

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  14. Content type: Review

    Schizophrenia is among the most disabling of mental illnesses and frequently causes impaired functioning. We explore issues of definition and terminology, and the relationship between social functioning, cogni...

    Authors: Sofia Brissos, Andrew Molodynski, Vasco Videira Dias and Maria Luísa Figueira

    Citation: Annals of General Psychiatry 2011 10:18

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  15. Content type: Primary research

    The idea that the impact of opioid agonist treatment is influenced by the psychopathological profile of heroin addicts has not yet been investigated, and is based on the concept of a specific therapeutic actio...

    Authors: Angelo Giovanni Icro Maremmani, Luca Rovai, Pier Paolo Pani, Matteo Pacini, Francesco Lamanna, Fabio Rugani, Elisa Schiavi, Liliana Dell'Osso and Icro Maremmani

    Citation: Annals of General Psychiatry 2011 10:17

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  16. Content type: Primary research

    Anorexia nervosa carries the highest mortality rate of any psychiatric disorder. Even the most critically ill anorexic patients may present with normal 'standard' laboratory values, underscoring the need for a...

    Authors: Michael A Flierl, Jennifer L Gaudiani, Allison L Sabel, Carlin S Long, Philip F Stahel and Philip S Mehler

    Citation: Annals of General Psychiatry 2011 10:16

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  17. Content type: Primary research

    Since 1958 many, but not all studies have demonstrated that paternal age is a risk factor for schizophrenia. There may be many different explanations for differences between studies, including study design, sa...

    Authors: Morteza Naserbakht, Hamid-Reza Ahmadkhaniha, Bahareh Mokri and Cassandra L Smith

    Citation: Annals of General Psychiatry 2011 10:15

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  18. Content type: Primary research

    The 'double-diamond copy' task is a simple paper and pencil test part of the Bender-Gestalt Test and the Mini Mental State Examination (MMSE). Although it is a widely used test, its method of scoring is crude ...

    Authors: Konstantinos N Fountoulakis, Melina Siamouli, Panagiotis T Panagiotidis, Stamatia Magiria, Sotiris Kantartzis, Vassiliki A Terzoglou and Timucin Oral

    Citation: Annals of General Psychiatry 2011 10:13

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  19. Content type: Primary research

    This post hoc analysis (trial registration: ClinicalTrials.gov NCT00590577) assessed onset of efficacy and tolerability of acute treatment with once-monthly paliperidone palmitate (PP), a long-acting atypical ...

    Authors: Larry Alphs, Cynthia A Bossie, Jennifer K Sliwa, Yi-Wen Ma and Norris Turner

    Citation: Annals of General Psychiatry 2011 10:12

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  20. Content type: Primary research

    In Japan, hospitalization for the assessment of mentally disordered offenders under the Act on Medical Care and Treatment for the Persons Who Had Caused Serious Cases under the Condition of Insanity (the Medic...

    Authors: Akihiro Shiina, Mihisa Fujisaki, Takako Nagata, Yasunori Oda, Masatoshi Suzuki, Masahiro Yoshizawa, Masaomi Iyo and Yoshito Igarashi

    Citation: Annals of General Psychiatry 2011 10:11

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  21. Content type: Primary research

    Because wide variations in mental health care utilization exist throughout the world, determining long-term effectiveness of psychotropic medications in a real-world setting would be beneficial to physicians a...

    Authors: Tim Lambert, José M Olivares, Joseph Peuskens, Cherilyn DeSouza, Chris M Kozma, Patrick Otten, Concetta Crivera, An Jacobs, Wayne Macfadden, Lian Mao, Stephen C Rodriguez, Riad Dirani and Kasem S Akhras

    Citation: Annals of General Psychiatry 2011 10:10

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  22. Content type: Review

    Due to the relationship between biology and culture, we believe that depression, understood as a cultural and existential phenomenon, has clear markers in molecular biology. We begin from an existential analys...

    Authors: Massimo Cocchi, Lucio Tonello, Fabio Gabrielli and Massimo Pregnolato

    Citation: Annals of General Psychiatry 2011 10:9

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  23. Content type: Review

    Anecdotal reports suggests that most clinicians treat medications as belonging to a class with regard to all therapeutic indications; this means that the whole 'class' of drugs is considered to possesses a spe...

    Authors: Konstantinos N Fountoulakis, Xenia Gonda, Eduard Vieta and Zoltan Rihmer

    Citation: Annals of General Psychiatry 2011 10:8

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  24. Content type: Primary research

    We assessed the impact of generalised anxiety disorder (GAD) on disability and health-related quality of life in outpatients treated in psychiatric clinics via a secondary analysis conducted in 799 patients fr...

    Authors: Julio Bobes, Luis Caballero, Inma Vilardaga and Javier Rejas

    Citation: Annals of General Psychiatry 2011 10:7

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  25. Content type: Primary research

    Perception of quality of life may differ depending on the perspective. The aim of the study was to assess the psychometric properties of the Spanish version of the 'TOlerability and quality Of Life' (TOOL) que...

    Authors: Angel L Montejo, Javier Correas Lauffer, Jesús Cuervo, Pablo Rebollo, Luis Cordero, Teresa Diez and Jorge Maurino

    Citation: Annals of General Psychiatry 2011 10:6

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  26. Content type: Primary research

    Serotonin reuptake inhibitors (SRIs) currently represent the cornerstone of obsessive-compulsive disorder (OCD) pharmacotherapy. However, OCD is characterized by high rates of partial and/or absent response to...

    Authors: Michele Fornaro

    Citation: Annals of General Psychiatry 2011 10:5

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  27. Content type: Primary research

    Schizophrenia is a chronic and disabling disease that presents with delusions and hallucinations. Auditory hallucinations are usually expressed as voices speaking to or about the patient. Previous studies have...

    Authors: Oded Rosenberg, Yiftach Roth, Moshe Kotler, Abraham Zangen and Pinhas Dannon

    Citation: Annals of General Psychiatry 2011 10:3

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  28. Content type: Primary research

    Recent analyses of antiepileptic drugs have indicated an increase in the risk of suicidality. The objective of this report was to provide clinical information and an independent meta-analysis of divalproex sod...

    Authors: Laura Redden, Yili Pritchett, Weining Robieson, Xenia Kovacs, Mary Garofalo, Katherine Tracy and Mario Saltarelli

    Citation: Annals of General Psychiatry 2011 10:1

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  29. Content type: Review

    It has been hypothesised that people with anorexia nervosa have a higher intelligence quotient (IQ) level than the general population. The purpose of this review was to systematically appraise the research int...

    Authors: Carolina Lopez, Daniel Stahl and Kate Tchanturia

    Citation: Annals of General Psychiatry 2010 9:40

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  30. Content type: Case report

    Poor-insight obsessive-compulsive disorder (PI-OCD) is a severe form of OCD where the 'typically obsessive' features of intrusive, 'egodystonic' feelings and thoughts are absent. PI-OCD is difficult to treat, ...

    Authors: Michele Fornaro and Matteo Martino

    Citation: Annals of General Psychiatry 2010 9:39

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  31. Content type: Primary research

    Benzodiazepines carry the risk of inducing cognitive impairments, which may go unnoticed while profoundly disturbing social activity. Furthermore, these impairments are partly associated with the elimination h...

    Authors: Goro Fukami, Tasuku Hashimoto, Yukihiko Shirayama, Tadashi Hasegawa, Hiroyuki Watanabe, Mihisa Fujisaki, Kenji Hashimoto and Masaomi Iyo

    Citation: Annals of General Psychiatry 2010 9:37

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  32. Content type: Primary research

    The purpose of this study was to investigate the variations of paraoxonase activity and lipid profile in bipolar I patients, and the association of this activity with the sociodemographic, clinical and therape...

    Authors: Asma Ezzaher, Dhouha Haj Mouhamed, Anwar Mechri, Manel Araoud, Fadoua Neffati, Wahiba Douki, Lotfi Gaha and Mohamed Fadhel Najjar

    Citation: Annals of General Psychiatry 2010 9:36

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  33. Content type: Primary research

    To evaluate the overall long-term effectiveness of aripiprazole in patients with schizophrenia in a general psychiatric practice setting in Taiwan.

    Authors: Ming-Hong Hsieh, Wei-Wen Lin, Shao-Tsu Chen, Kao-Ching Chen, Kuang-Peng Chen, Nan-Ying Chiu, Chao Huang, Ching-Jui Chang, Cheng-Hsiu Lin and Te-Jen Lai

    Citation: Annals of General Psychiatry 2010 9:35

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  34. Content type: Primary research

    Factors Influencing Depression Endpoints Research (FINDER) is a 6-month, prospective, observational study carried out in 12 European countries aimed at investigating health-related quality of life (HRQoL) in o...

    Authors: Rosangela Caruso, Andrea Rossi, Alessandra Barraco, Deborah Quail and Luigi Grassi

    Citation: Annals of General Psychiatry 2010 9:33

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  35. Content type: Primary research

    The aim of the study was to examine the combined effect of gender and age on post traumatic stress disorder (PTSD) in order to describe a possible gender difference in the lifespan distribution of PTSD.

    Authors: Daniel N Ditlevsen and Ask Elklit

    Citation: Annals of General Psychiatry 2010 9:32

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  36. Content type: Primary research

    Many researchers and clinicians have proposed using virtual reality (VR) in adjunct to in vivo exposure therapy to provide an innovative form of exposure to patients suffering from different psychological disorde...

    Authors: Alessandra Gorini, Eric Griez, Anna Petrova and Giuseppe Riva

    Citation: Annals of General Psychiatry 2010 9:30

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  37. Content type: Primary research

    Set-shifting is impaired in people with anorexia nervosa (AN), but the underlying physiological and biochemical processes are unclear. Animal studies have established that glutamatergic pathways in the prefron...

    Authors: Michiko Nakazato, Kenji Hashimoto, Ulrike Schmidt, Kate Tchanturia, Iain C Campbell, David A Collier, Masaomi Iyo and Janet Treasure

    Citation: Annals of General Psychiatry 2010 9:29

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  38. Content type: Primary research

    Cognitive deficits in schizophrenia are associated with psychosocial deficits that are primarily responsible for the poor long-term outcome of this disease. Auditory sensory gating P50 deficits are correlated ...

    Authors: Akihiro Shiina, Yukihiko Shirayama, Tomihisa Niitsu, Tasuku Hashimoto, Taisuke Yoshida, Tadashi Hasegawa, Tadashi Haraguchi, Nobuhisa Kanahara, Tetsuya Shiraishi, Mihisa Fujisaki, Goro Fukami, Michiko Nakazato, Masaomi Iyo and Kenji Hashimoto

    Citation: Annals of General Psychiatry 2010 9:27

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  39. Content type: Primary research

    The aim of this paper was to study the collaboration between emergency departments (EDs) in general hospitals and community health services (CHS) in Norway when providing psychosocial care and aftercare to pat...

    Authors: Erlend Mork, Lars Mehlum, Elin Anita Fadum and Ingeborg Rossow

    Citation: Annals of General Psychiatry 2010 9:26

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  40. Content type: Review

    The biomolecular approach to major depression disorder is explained by the different steps that involve cell membrane viscosity, Gsα protein and tubulin. For the first time it is hypothesised that a biomolecul...

    Authors: Massimo Cocchi, Lucio Tonello and Mark M Rasenick

    Citation: Annals of General Psychiatry 2010 9:25

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  41. Content type: Primary research

    The purpose of this analysis was to evaluate relationships between hospital admission or discharge and scores for symptom or functioning in patients with schizophrenia.

    Authors: Chris M Kozma, Riad G Dirani, Carla M Canuso and Lian Mao

    Citation: Annals of General Psychiatry 2010 9:24

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