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  1. Migraine has been associated with mental disorders, however whether parental migraine is associated with an increased risk of major mental disorders (MMDs) in offspring has not been investigated. We aimed to e...

    Authors: Dian-Jeng Li, Shih-Jen Tsai, Tzeng-Ji Chen, Chih-Sung Liang and Mu-Hong Chen
    Citation: Annals of General Psychiatry 2024 23:23
  2. This study aimed to assess the incidence of EEG abnormalities (EEG-ab) in children diagnosed with ADHD, investigate the risk of epileptic seizures (SZ) and maintenance on methylphenidate (MPH) over a three-yea...

    Authors: Dobrinko Socanski, Geir Ogrim and Nezla Duric
    Citation: Annals of General Psychiatry 2024 23:22
  3. Personality disorders (PD) are described as enduring patterns of markedly deviant and pervasive inner experiences and behaviors, with onset in adolescence, which lead to severe distress or impairment. Patients...

    Authors: Carmine Tomasetti, G. Autullo, A. Ballerini, A. de Bartolomeis, B. Dell’Osso, A. Fiorentini, F. Tonioni, V. Villari and D. De Berardis
    Citation: Annals of General Psychiatry 2024 23:21
  4. Depression is a highly heterogeneous disorder, often resulting in suboptimal response and remission rates. This underscores the need for more nuanced clinical characterization of patients to tailor individuali...

    Authors: Alessandro Cuomo, Andrea Aguglia, Domenico De Berardis, Antonio Ventriglio, Camilla Gesi and Andrea Fagiolini
    Citation: Annals of General Psychiatry 2024 23:20
  5. Anxiety disorders can cause serious physical and psychological damage, so many anxiety scales have been developed internationally to measure anxiety disorders, but due to the cultural differences and cultural ...

    Authors: Hongqiang Shi, Yu Ren, Junding Xian, Haifeng Ding, Yuxi Liu and Chonghua Wan
    Citation: Annals of General Psychiatry 2024 23:19
  6. Formal coercion in psychiatry is widely studied yet much less is known about pressures patients may experience, partly because of the very few measures available. The goal of this study was to validate the P-P...

    Authors: Philippe Golay, Debora Martinez, Mizué Bachelard, Benedetta Silva, Alexandra Brodard, Jonathan Perrin, Nolan Pedro Fernando, Lou-Ann Renaud, Charles Bonsack and Stéphane Morandi
    Citation: Annals of General Psychiatry 2024 23:18
  7. While depression is increasing worldwide, some patients are diagnosed as having Major Depressive Disorder (MDD), but others are diagnosed with minor depression, however, the potential neuro mechanism is unknown.

    Authors: Gaizhi Li, Ke Ma, Kathryn Rossbach, Ying Niu, Qiqi Li, Zhifen Liu and Kerang Zhang
    Citation: Annals of General Psychiatry 2024 23:17
  8. Adolescents with depression who engage in non-suicidal self harming behaviors are more likely to adopt negative coping strategies when faced with negative events. Therefore, these patients should be introduced...

    Authors: Xiao-Fen Fan, Ju-Yi Peng, Li Zhang, Ya-Li Hu, Yan Li, Yue Shi and Tian-Mei Zhang
    Citation: Annals of General Psychiatry 2024 23:16
  9. Patients with mood disorders usually require repeated and prolonged hospitalization, resulting in a heavy burden on healthcare resources. This study aims to identify variables associated with length of stay(LO...

    Authors: Feng Xu, Peixia Cheng, Jiaying Xu, Xiaonan Wang, Zhen Jiang, Huiping Zhu, Hua Fan, Qian Wang and Qi Gao
    Citation: Annals of General Psychiatry 2024 23:15
  10. There is substantial evidence that people with mental illness have higher mortality rates than the general population. However, most of the studies were from Western countries, and it is not clear whether this...

    Authors: Sami Ouanes, Lien Abou Hashem, Ibrahim Makki, Faisal Khan, Omer Mahgoub, Ahmed Wafer, Omer Dulaimy, Raed Amro and Suhaila Ghuloum
    Citation: Annals of General Psychiatry 2024 23:14
  11. Bipolar disorder (BD) is a chronic psychiatric disorder that combines hypomania or mania and depression. The study aims to investigate the research areas associated with cognitive function in bipolar disorder ...

    Authors: Xiaohong Cui, Tailian Xue, Zhiyong Zhang, Hong Yang and Yan Ren
    Citation: Annals of General Psychiatry 2024 23:13
  12. Hikikomori (HK) is characterized by self-isolation and social refusal, being more likely also associated with affective disorders, including depression. This case–control study primarily aimed at identifying (...

    Authors: Laura Orsolini, Giulio Longo, Silvia Bellagamba, Takahiro A. Kato and Umberto Volpe
    Citation: Annals of General Psychiatry 2024 23:12
  13. Epilepsy is one of the most common neurologic conditions. Its clinical manifestations are not restricted to seizures but often include cognitive disturbances and psychiatric disorders. Prospective population-b...

    Authors: Andres M. Kanner, Rohit Shankar, Nils G. Margraf, Bettina Schmitz, Elinor Ben-Menachem and Josemir W. Sander
    Citation: Annals of General Psychiatry 2024 23:11
  14. Post-COVID-19 Condition (PCC), as defined by the World Health Organization (WHO), currently lacks any regulatory-approved treatments and is characterized by persistent and debilitating cognitive impairment and...

    Authors: Angela T.H. Kwan, Gia Han Le, Ziji Guo, Felicia Ceban, Kayla M. Teopiz, Taeho Greg Rhee, Roger Ho, Joshua D. Di Vincenzo, Sebastian Badulescu, Shakila Meshkat, Bing Cao, Joshua D. Rosenblat, Donovan A. Dev, Lee Phan, Mehala Subramaniapillai and Roger S. McIntyre
    Citation: Annals of General Psychiatry 2024 23:10
  15. Studies suggest a correlation between excessive sedentary behavior, insufficient physical activity, and an elevated likelihood of experiencing psychiatric disorder. Nonetheless, the precise influence of sedent...

    Authors: Hongjun Ba, Lili Zhang, Huimin Peng, Xiufang He and Yao Wang
    Citation: Annals of General Psychiatry 2024 23:9
  16. Major depressive disorder (MDD) is predicted to become the second most common cause of disability in the near future. Exposure to glyphosate (Gly)-based herbicides has been linked to the onset of MDD. However,...

    Authors: Jianan Li and Haoran Bi
    Citation: Annals of General Psychiatry 2024 23:8
  17. Facing suicide risk is probably the most difficult task for clinicians when dealing with patients in crisis. It requires professional, intellectual, and emotional efforts. Suicide risk assessment can sometimes...

    Authors: Maurizio Pompili
    Citation: Annals of General Psychiatry 2024 23:6
  18. Being one of the most widespread, pervasive, and troublesome illnesses in the world, depression causes dysfunction in various spheres of individual and social life. Regrettably, despite obtaining evidence-base...

    Authors: Yupei Hao, Jinyuan Zhang, Jing Yu, Ze Yu, Lin Yang, Xin Hao, Fei Gao and Chunhua Zhou
    Citation: Annals of General Psychiatry 2024 23:5
  19. The present study aimed at assessing the prevalences of post-traumatic stress disorder (PTSD) (main objective), anxiety, depression, and burnout syndrome (BOS) and their associated factors in intensive care un...

    Authors: Claire Roger, Lowel Ling, Mélissa Petrier, Loubna Elotmani, Enora Atchade, Bernard Allaouchiche, Frédéric Aubrun, Jean-Michel Constantin, Claire Dahyot-Fizelier, Nathalie Delhaye, Hervé Dupont, Marc-Olivier Fischer, Marc Garnier, Etienne Gayat, Carole Ichai, Samir Jaber…
    Citation: Annals of General Psychiatry 2024 23:3
  20. A change of therapy from one to another antipsychotic medication is currently the main challenge of therapy. This study aimed to assess the prevalence of antipsychotic medication switches and determinants amon...

    Authors: Mekdes Kiflu, Telake Azale, Kale Gubae, Samuel Agegnew Wondm, Ephrem Mebratu, Asrat EliasErgena, Ousman Abubeker and Gizework Alemnew Mekonnen
    Citation: Annals of General Psychiatry 2024 23:2
  21. Weight gain in the months/years after diagnosis/treatment of severe enduring mental illness (SMI) is a major predictor of future diabetes, dysmetabolic profile and increased risk of cardiometabolic diseases. T...

    Authors: Adrian Heald, Chris Daly, John Julian Warner-Levy, Richard Williams, Cheyenne Meehan, Mark Livingston, Toby Pillinger, Lamiece Hussain and Joseph Firth
    Citation: Annals of General Psychiatry 2024 23:1
  22. It is known worldwide that stigma towards mental illness exists. Studies on stigma perceived by patients with mental illness have shown decreased quality of life and a negative impact on work, school and socia...

    Authors: Areej AlFattani, Lisa Bilal, Sami Y. Saad, Mohammad Talal Naseem, Sanaa Hyder, Abdulhamid Alhabib, Abdullah Alsubaie and Yasmin Altwaijri
    Citation: Annals of General Psychiatry 2023 22:54
  23. Major depressive disorder (MDD) is a leading mental disorder causing severe impairment. This study was aimed to evaluate sex difference in global MDD incidence by year, age, and socioeconomic status, according...

    Authors: Sangzi Li, Xuan Zhang, Yilu Cai, Leilei Zheng, Hu Pang and Lixia Lou
    Citation: Annals of General Psychiatry 2023 22:53
  24. Bipolar disorder is a mental illness characterized by recurring episodes of mania and depression and is known to cause social impairment. Additionally, it has been revealed that bipolar disorder increases the ...

    Authors: Keita Tokumitsu, Norio Sugawara, Naoto Adachi, Yukihisa Kubota, Yoichiro Watanabe, Kazuhira Miki, Takaharu Azekawa, Koji Edagawa, Eiichi Katsumoto, Seiji Hongo, Eiichiro Goto, Hitoshi Ueda, Masaki Kato, Reiji Yoshimura, Atsuo Nakagawa, Toshiaki Kikuchi…
    Citation: Annals of General Psychiatry 2023 22:52
  25. Major depressive disorder (MDD) is a major and common cause of suicide. The purpose of this article is to report the clinical characteristics and patterns of co-morbid suicidal behavior (SB) in first hospitali...

    Authors: Xianzhi Sun, Lili Yin, Yingying Zhang, Xuebing Liu and Jun Ma
    Citation: Annals of General Psychiatry 2023 22:51
  26. Bipolar disorder is one of the most burdensome severe mental disorders, characterized by high levels of personal and social disability. Patients often need an integrated pharmacological and non-pharmacological...

    Authors: Andrea Fiorillo, Gaia Sampogna, Umberto Albert, Giuseppe Maina, Giulio Perugi, Maurizio Pompili, Gianluca Rosso, Gabriele Sani and Alfonso Tortorella
    Citation: Annals of General Psychiatry 2023 22:50
  27. Factors influencing antidepressant treatment discontinuation are poorly understood. In the present study, we aimed to estimate the prevalence of antidepressant treatment discontinuation and identify demographi...

    Authors: Luis M. Garcia-Marin, Aoibhe Mulcahy, Enda M. Byrne, Sarah E. Medland, Naomi R. Wray, Freddy Chafota, Penelope A. Lind, Nicholas G. Martin, Ian B. Hickie, Miguel E. Rentería and Adrian I. Campos
    Citation: Annals of General Psychiatry 2023 22:49
  28. Treatment-resistant depression (TRD) is defined by the European Medicines Agency as a lack of clinically meaningful improvement after treatment, with at least two different antidepressants. Individual, familia...

    Authors: Giuseppe Maina, Marina Adami, Giuseppe Ascione, Emi Bondi, Domenico De Berardis, Dario Delmonte, Silvia Maffezzoli, Giovanni Martinotti, Alessandra Nivoli, Elena Ottavianelli and Andrea Fagiolini
    Citation: Annals of General Psychiatry 2023 22:48
  29. Major depressive disorder (MDD) poses a significant social and economic burden worldwide. Identifying exposures, risk factors, and biological mechanisms that are causally connected to MDD can help build a scie...

    Authors: Wang-ran Ma, Lei-lei Zhang, Jing-ying Ma, Fang Yu, Ya-qing Hou, Xiang-rui Feng and Lin Yang
    Citation: Annals of General Psychiatry 2023 22:47
  30. To evaluate the clinical efficacy and safety of Agomelatine in improving symptoms in patients with major depressive disorder (MDD), providing more scientific evidence for the treatment of depression, and offer...

    Authors: Ping Guo, Yong Xu, Liang Lv, Min Feng, Yu Fang, Wei-Quan Huang, Shan-Fei Cheng, Min-Cai Qian, Shengliang Yang, Shi-Kai Wang and Huan-Xin Chen
    Citation: Annals of General Psychiatry 2023 22:46
  31. There is a critical need for effective treatment of the core symptoms of autism spectrum disorder (ASD). The purinergic antagonist suramin may improve core symptoms through restoration of normal mitochondrial ...

    Authors: David Hough, Alice R. Mao, Michael Aman, Reymundo Lozano, Constance Smith-Hicks, Veronica Martinez-Cerdeno, Michael Derby, Zachary Rome, Niel Malan and Robert L. Findling
    Citation: Annals of General Psychiatry 2023 22:45
  32. The digital transformation has made its way into many areas of society, including medicine. While AI-based systems are widespread in medical disciplines, their use in psychiatry is progressing more slowly. How...

    Authors: Saskia Wilhelmy, Giancarlo Giupponi, Dominik Groß, Klaus Eisendle and Andreas Conca
    Citation: Annals of General Psychiatry 2023 22:43
  33. There is a conceptual overlap between negative and depressive symptoms, requiring further exploration to advance the understanding of negative symptoms. The aim of this study was to examine psychometric proper...

    Authors: Johan Bengtsson, Parya Rad, Martin Cernvall and Robert Bodén
    Citation: Annals of General Psychiatry 2023 22:42
  34. The COVID-19 pandemic emerged as an expected source of stress and anxiety as the healthcare workers had to work for long hours in close contact with infected patients, thus increasing the probability of medica...

    Authors: Hasan Nabil Al Houri, Abdullah Alhouri, Douaa Mohammad Nazir Arrouk, Ahmad Nabil Al Houri, Sami Jomaa, Alaa Sharabi, Hussein Kannout and Youssef Latifeh
    Citation: Annals of General Psychiatry 2023 22:41
  35. Schizophrenia is a serious mental disorder with complex clinical manifestations, while its pathophysiological mechanism is not fully understood. Accumulated evidence suggested the alteration in epigenetic path...

    Authors: Junjiao Ping, Jing Wan, Caiying Huang, Jinming Yu, Jiali Luo, Zhiqiang Xing, Xingguang Luo, Baoguo Du, Tingyun Jiang and Jie Zhang
    Citation: Annals of General Psychiatry 2023 22:40
  36. In Kalhbaum's first characterization of catatonia, the emotional symptoms, such as decreased or restricted expression of feelings and emotions, which is described as blunted affect, are related to the motor sy...

    Authors: Antonino Messina, Filippo Caraci, Eugenio Aguglia and Maria Salvina Signorelli
    Citation: Annals of General Psychiatry 2023 22:39
  37. The coronavirus disease 2019 (COVID-19) pandemic was reported to have increased depression among university students which was associated with impairments in their campus lives. This study examined changes in ...

    Authors: N. Shiraishi, M. Sakata, R. Toyomoto, K. Yoshida, Y. Luo, Y. Nakagami, A. Tajika, T. Watanabe, E. Sahker, T. Uwatoko, T. Shimamoto, T. Iwami and T. A. Furukawa
    Citation: Annals of General Psychiatry 2023 22:38
  38. Blonanserin (BNS) had been undergoing post-market surveillance (PMS) since September 2018. Using the surveillance data, we did this analysis to assess the safety and effectiveness of different doses of BNS to ...

    Authors: Yuan Yang, Hongmin Ge, Xijin Wang, Xuejun Liu, Keqing Li, Gang Wang, Xiaodong Yang, Huaili Deng, Meijuan Sun, Ruiling Zhang, Jindong Chen, Duanfang Cai, Hong Sang, Xianglai Liu, Guilai Zhan, Guijun Zhao…
    Citation: Annals of General Psychiatry 2023 22:37
  39. Many patients with depression refuse treatment. Moreover, suicide attempters often display low perceived need of treatment and impaired decision-making. These observations raise questions about the capacity to...

    Authors: Emilie Olié, Thomas Catanzaro, Manon Malestroit, Julio A. Guija, Lucas Giner and Philippe Courtet
    Citation: Annals of General Psychiatry 2023 22:35
  40. Risperidone ISM® is a newly developed long-acting injectable (LAI) treatment for schizophrenia in adults. In the absence of head-to-head comparisons with other similar antipsychotics, the objective of this study ...

    Authors: Pedro Sánchez, Cecilio Álamo, Marcos Almendros, Max Schlueter, Anastasios Tasoulas and Javier Martínez
    Citation: Annals of General Psychiatry 2023 22:33
  41. Major depressive disorder (MDD) is the most common mood disorder and a leading cause of disability worldwide. Trazodone, a triazolopyridine serotonin receptor antagonist and reuptake inhibitor (SARI) antidepre...

    Authors: Andrea Fagiolini, Ana González-Pinto, Kamilla Woznica Miskowiak, Pedro Morgado, Allan H. Young and Eduard Vieta
    Citation: Annals of General Psychiatry 2023 22:32
  42. In China, adolescents account for about a quarter of those treated for mental disorders each year, and adolescent mental health issues have become a social hotspot. Although several epidemiological surveys of ...

    Authors: Shuangyi Pei, Xiaoting Wu, Weijiang Ye, Linqi Fang, Haoqiang Zhang, Fanghua Zhou, Xiaofei Du, Xinyi Cao, Shengnan Ma, Yuanchu Li, Shuwen Xi and Pingping Xu
    Citation: Annals of General Psychiatry 2023 22:31
  43. In China, patients with somatoform disorders (SFD) often seek medical treatment repeatedly in outpatient clinics of general hospitals, which increases unreasonable medical expenses. It is imperative to provide...

    Authors: Xiangyun Yang, Jia Luo, Pengchong Wang, Yue He, Cong Wang, Lijuan Yang, Jing Sun and Zhanjiang Li
    Citation: Annals of General Psychiatry 2023 22:30
  44. Despite autism spectrum disorder (ASD) and mentalization being two words often associated in the literature, the assessment of this ability in individuals with ASD in the clinical setting is still limited. Ind...

    Authors: Ilenia Le Donne, Margherita Attanasio, Antony Bologna, Roberto Vagnetti, Francesco Masedu, Marco Valenti and Monica Mazza
    Citation: Annals of General Psychiatry 2023 22:29
  45. The aim of this meta-analysis was to determine global pooled prevalence of suicide thoughts and attempts in transgender population.

    Authors: Parisa Kohnepoushi, Maziar Nikouei, Mojtaba Cheraghi, Parsa Hasanabadi, Hamza Rahmani, Maryam Moradi, Ghobad Moradi, Farhad Moradpour and Yousef Moradi
    Citation: Annals of General Psychiatry 2023 22:28