Gender difference in QTc prolongation of people with mental disorders

Table 1 Variables used in the study and their locations in the statistical model of each analysis.

Variable (with values and their codes for qualitative variables)		t-test	two-way ANCOVAs¹⁾	one-way ANCOVAs
gender		indep.var.	factor^a)	factor
0	male
1	female
age at admission			covariate	covariate
diagnosis			factor^b)
0	others
1	schizoperenia
2	mood disorders
antipsychotics²⁾			factor^b)
0	0 mg
1	0–100 mg
2	100–500 mg
3	500 mg +
antidepressants³⁾			factor^b)
0	0 mg
1	0–50 mg
2	50–100 mg
3	100 mg +
cardiovascular disease			factor^b)
0	absent
1	present
cardiovascular disease			factor^b)
0	absent
1	present
hepatic failure			factor^b)
0	absent
1	present
diabetes			factor^b)
0	absent
1	present
QTc interval		dep.var.	dep.var.	dep.var.

indep.var. = independent variable dep.var. = dependent variable 1) We included gender (marked with 'a') as one factor, and one of the other qualitative variables (marked with 'b') as the other, therefore we carried out 7 two-way ANCOVAs in total. 2) Dose of antipsychotics was estimated in chlorpromazine equivalents. 3) Dose of antidepressants was estimated in maprotiline equivalents.

ISSN: 1744-859X